Skip Header

Contribute Send feedback
Read comments (?) or add your own

B2SM84 (MTNC_XANOP) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Enolase-phosphatase E1
EC=3.1.3.77
Alternative name(s):
2,3-diketo-5-methylthio-1-phosphopentane phosphatase
Gene names
Name:mtnC1
Ordered Locus Names:PXO_00846
AND
Name:mtnC2
Ordered Locus Names:PXO_06081
OrganismXanthomonas oryzae pv. oryzae (strain PXO99A) [Complete proteome] [HAMAP]
Taxonomic identifier360094 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) By similarity. HAMAP MF_01681

Catalytic activity

5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. HAMAP MF_01681

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01681

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6. HAMAP MF_01681

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.

Subunit structure

Monomer By similarity. HAMAP MF_01681

Sequence similarities

Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 232232Enolase-phosphatase E1 HAMAP MF_01681
PRO_0000357434

Sequences

Sequence LengthMass (Da)Tools
B2SM84 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 89F746D4016C8418

FASTA23225,990
        10         20         30         40         50         60 
MTRPQAILTD IEGTTSSISF VKDVLFPYAR RAMPAYVREH GNHPQVRHWL NQVADEIGED 

        70         80         90        100        110        120 
VPDDVLITTL QTWIDEDRKH TALKALQGLI WGEGYKIADF TAHMYADAAL QLQAWHAAGI 

       130        140        150        160        170        180 
PLYVYSSGSV PAQKLFFAHS DAGDLSGLVS DWFDTEVGSK REAASYRRIA ERIGVPASEI 

       190        200        210        220        230 
LFLSDVIEEL DAAKRTGMRT ALLERREDYP TPRSADDVGS HQRVENFSQL VF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000967 Genomic DNA. Translation: ACD59084.1.
CP000967 Genomic DNA. Translation: ACD59275.1.
RefSeqYP_001913616.1. NC_010717.1.
YP_001913807.1. NC_010717.1.

3D structure databases

ProteinModelPortalB2SM84.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2SM84.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6305992.
6306186.
GenomeReviewsGene locus PXO_00846 in contig CP000967_GR.
Gene locus PXO_06081 in contig CP000967_GR.
KEGGxop:PXO_00846.
xop:PXO_06081.
PATRIC24124365. VBIXanOry73153_2539.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG294242.
OMATTDLNFI.
ProtClustDBCLSK866737.

Enzyme and pathway databases

BioCycXORY360094:XOOORF_2539-MONOMER.
XORY360094:XOOORF_2735-MONOMER.

Family and domain databases

HAMAPMF_01681. Salvage_MtnC.
[Tree]
InterProIPR005834. Dehalogen-like_hydro.
IPR023943. Enolase-phosphatase_E1.
IPR010041. Enolase_ppase.
IPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA_v1.
IPR005833. Haloacid_DH/epoxide_hydro.
[Graphical view]
Gene3DG3DSA:3.40.50.1000. HAD-like_dom. 1 hit.
KOK09880.
PfamPF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSPR00413. HADHALOGNASE.
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01691. Enolase-ppase. 1 hit.
TIGR01549. HAD-SF-IA-v1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMTNC_XANOP
AccessionPrimary (citable) accession number: B2SM84
Entry history
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: July 1, 2008
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents