Isocitrate dehydrogenase, NADP-dependent - Xanthomonas oryzae pv. oryzae (strain PXO99A)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase, NADP-dependent EMBL ACD57270.1

Gene names

Ordered Locus Names:

PXO_03994 EMBL ACD57270.1

Organism

Xanthomonas oryzae pv. oryzae (strain PXO99A) [Complete proteome] [HAMAP] EMBL ACD57270.1

Taxonomic identifier

360094 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas ›

Protein attributes

Sequence length	743 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Region

133 – 140

8

Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding

351

1

Magnesium or manganese By similarity PIRSR PIRSR009407-3

Metal binding

549

1

Magnesium or manganese By similarity PIRSR PIRSR009407-3

Metal binding

553

1

Magnesium or manganese By similarity PIRSR PIRSR009407-3

Binding site

146

1

Substrate By similarity PIRSR PIRSR009407-2

Binding site

548

1

Substrate By similarity PIRSR PIRSR009407-2

Site

256

1

Critical for catalysis By similarity PIRSR PIRSR009407-1

Site

421

1

Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence

Length

Mass (Da)

Tools

B2SKD3 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 818A13A1CED92798
Show »

FASTA

743

80,342

        10         20         30         40         50         60 
MPNTPKILYT LTDEAPYLAT QSLLPIIDAY TDTAGIVVET RDISLAGRIL ALFPEYLSDT 

        70         80         90        100        110        120 
QKVADDLGEL GELATTPEAN IIKLPNISAS VPQLKAAIKE LQGQGYALPA YPDEPKDAAE 

       130        140        150        160        170        180 
KDIKARYDKV KGSAVNPVLR EGNSDRRAPL SVKNYARKHP HRMGKWSSDS KSHVSHMESG 

       190        200        210        220        230        240 
DFFGSEQSTT LADAGTLKIE FVGADGSSTV LKDKVAVKAG EIVDAAVLSK RALASFIDAQ 

       250        260        270        280        290        300 
IADAKARDVL FSVHLKATMM KVSDPVLFGV VVGEFYKDTL SRHADALKSV GFDPNNGIGD 

       310        320        330        340        350        360 
LYARIGTLPE DQQARIKADI QAEYAQRPGL AMVNSDKGIT NLHVPSDVIV DASMPAMIRD 

       370        380        390        400        410        420 
SGQMWNAQGT LQDTKAVIPD RCYADVYQAV IDDCKAHGAF DPSTMGSVPN VGLMAQKAEE 

       430        440        450        460        470        480 
YGSHDKTFQM AAAGTVKVTD GNGKTVFKHA VEAGDLWRMC QVKDAPIQDW VKLAVERARL 

       490        500        510        520        530        540 
SDTPAVFWLD QARAHDAQVI AKVEQYLKDH DTNGLDIRIL PPVEATAFSL ERIRKGQDTI 

       550        560        570        580        590        600 
SVTGNVLRDY LTDLFPIMEL GTSAKMLSIV PLMAGGGLFE TGAGGSAPKH VQQFVEENCL 

       610        620        630        640        650        660 
RWDSLGEFLA LAASLEHLGN RYDNPSATVL AKALDVANGQ FLDNNKSPAR KVGELDNRGS 

       670        680        690        700        710        720 
HFYLAMYWAQ ALAAQTEDTA LQGRFAPLAR ALTENEATIV AELNGAQGKP VDIGGYYHPD 

       730        740 
LAKVSEAMRP SKTFNDILAT LKA

« Hide

References

[1]

"Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99A."
Salzberg S.L., Sommer D.D., Schatz M.C., Phillippy A.M., Rabinowicz P.D., Tsuge S., Furutani A., Ochiai H., Delcher A.L., Kelley D., Madupu R., Puiu D., Radune D., Shumway M., Trapnell C., Aparna G., Jha G., Pandey A.

Bogdanove A.J.
BMC Genomics 9:204-204(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PXO99A EMBL ACD57270.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000967 Genomic DNA. Translation: ACD57270.1.
RefSeq	YP_001911802.1. NC_010717.1.
3D structure databases
ProteinModelPortal	B2SKD3.
SMR	B2SKD3. Positions 4-741.
ModBase	Search...
Protein-protein interaction databases
STRING	360094.PXO_03994.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACD57270; ACD57270; PXO_03994.
GeneID	6304135.
KEGG	xop:PXO_03994.
PATRIC	24120514. VBIXanOry73153_0639.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2838.
HOGENOM	HOG000240860.
KO	K00031.
OMA	FRMCQTK.
ProtClustDB	CLSK867411.
Family and domain databases
Gene3D	3.40.718.10. 3 hits.
InterPro	IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
Pfam	PF03971. IDH. 1 hit. [Graphical view]
PIRSF	PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMs	TIGR00178. monomer_idh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2SKD3_XANOP

Accession

Primary (citable) accession number: B2SKD3

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Regions

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry information