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B2SKD3

- B2SKD3_XANOP

UniProt

B2SKD3 - B2SKD3_XANOP

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

PXO_03994

Organism
Xanthomonas oryzae pv. oryzae (strain PXO99A)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (01 Jul 2008)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei146 – 1461SubstrateUniRule annotation
    Sitei256 – 2561Critical for catalysisUniRule annotation
    Metal bindingi351 – 3511Magnesium or manganeseUniRule annotation
    Sitei421 – 4211Critical for catalysisUniRule annotation
    Binding sitei548 – 5481SubstrateUniRule annotation
    Metal bindingi549 – 5491Magnesium or manganeseUniRule annotation
    Metal bindingi553 – 5531Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciXORY360094:GI45-616-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported
    Gene namesi
    Ordered Locus Names:PXO_03994Imported
    OrganismiXanthomonas oryzae pv. oryzae (strain PXO99A)Imported
    Taxonomic identifieri360094 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000001740: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi360094.PXO_03994.

    Structurei

    3D structure databases

    ProteinModelPortaliB2SKD3.
    SMRiB2SKD3. Positions 4-741.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni133 – 1408Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiARFDKIK.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B2SKD3-1 [UniParc]FASTAAdd to Basket

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    MPNTPKILYT LTDEAPYLAT QSLLPIIDAY TDTAGIVVET RDISLAGRIL    50
    ALFPEYLSDT QKVADDLGEL GELATTPEAN IIKLPNISAS VPQLKAAIKE 100
    LQGQGYALPA YPDEPKDAAE KDIKARYDKV KGSAVNPVLR EGNSDRRAPL 150
    SVKNYARKHP HRMGKWSSDS KSHVSHMESG DFFGSEQSTT LADAGTLKIE 200
    FVGADGSSTV LKDKVAVKAG EIVDAAVLSK RALASFIDAQ IADAKARDVL 250
    FSVHLKATMM KVSDPVLFGV VVGEFYKDTL SRHADALKSV GFDPNNGIGD 300
    LYARIGTLPE DQQARIKADI QAEYAQRPGL AMVNSDKGIT NLHVPSDVIV 350
    DASMPAMIRD SGQMWNAQGT LQDTKAVIPD RCYADVYQAV IDDCKAHGAF 400
    DPSTMGSVPN VGLMAQKAEE YGSHDKTFQM AAAGTVKVTD GNGKTVFKHA 450
    VEAGDLWRMC QVKDAPIQDW VKLAVERARL SDTPAVFWLD QARAHDAQVI 500
    AKVEQYLKDH DTNGLDIRIL PPVEATAFSL ERIRKGQDTI SVTGNVLRDY 550
    LTDLFPIMEL GTSAKMLSIV PLMAGGGLFE TGAGGSAPKH VQQFVEENCL 600
    RWDSLGEFLA LAASLEHLGN RYDNPSATVL AKALDVANGQ FLDNNKSPAR 650
    KVGELDNRGS HFYLAMYWAQ ALAAQTEDTA LQGRFAPLAR ALTENEATIV 700
    AELNGAQGKP VDIGGYYHPD LAKVSEAMRP SKTFNDILAT LKA 743
    Length:743
    Mass (Da):80,342
    Last modified:July 1, 2008 - v1
    Checksum:i818A13A1CED92798
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000967 Genomic DNA. Translation: ACD57270.1.
    RefSeqiWP_011409585.1. NC_010717.1.
    YP_001911802.1. NC_010717.1.

    Genome annotation databases

    EnsemblBacteriaiACD57270; ACD57270; PXO_03994.
    GeneIDi6304135.
    KEGGixop:PXO_03994.
    PATRICi24120514. VBIXanOry73153_0639.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000967 Genomic DNA. Translation: ACD57270.1 .
    RefSeqi WP_011409585.1. NC_010717.1.
    YP_001911802.1. NC_010717.1.

    3D structure databases

    ProteinModelPortali B2SKD3.
    SMRi B2SKD3. Positions 4-741.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 360094.PXO_03994.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACD57270 ; ACD57270 ; PXO_03994 .
    GeneIDi 6304135.
    KEGGi xop:PXO_03994.
    PATRICi 24120514. VBIXanOry73153_0639.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi ARFDKIK.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci XORY360094:GI45-616-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PXO99AImported.

    Entry informationi

    Entry nameiB2SKD3_XANOP
    AccessioniPrimary (citable) accession number: B2SKD3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 2008
    Last sequence update: July 1, 2008
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3