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B2SJL4

- GCH4_XANOP

UniProt

B2SJL4 - GCH4_XANOP

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Xanthomonas oryzae pv. oryzae (strain PXO99A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 2 (05 May 2009)
      Previous versions | rss
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    • Comment

    Functioni

    Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei154 – 1541May be catalytically importantUniRule annotation

    GO - Molecular functioni

    1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciXORY360094:GI45-2176-MONOMER.
    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
    Gene namesi
    Name:folE2UniRule annotation
    Ordered Locus Names:PXO_00695
    OrganismiXanthomonas oryzae pv. oryzae (strain PXO99A)
    Taxonomic identifieri360094 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000001740: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306GTP cyclohydrolase FolE2PRO_0000372037Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi360094.PXO_00695.

    Structurei

    3D structure databases

    ProteinModelPortaliB2SJL4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase IV family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1469.
    HOGENOMiHOG000247517.
    KOiK09007.
    OrthoDBiEOG6X6RBH.

    Family and domain databases

    HAMAPiMF_01527_B. GTP_cyclohydrol_B.
    InterProiIPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view]
    PfamiPF02649. GCHY-1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2SJL4-1 [UniParc]FASTAAdd to Basket

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    MSATLPDVAV TEAFTLSAPL RWVGMQDIAI PVHLDAASGS GLAARASVQV    50
    DLPRAELKGI HMSRLYRLLD LHLQRPLSPA MLPQLLQALI ESHADCASRA 100
    ARLTLSFALM LRMPALRSEG LSGWRAYPVR IAAQCRAGRT TIQLQVEVLY 150
    ASTCPCSAAL SRQLLSDAFV QQHAWCDALP LQDVAQWLQD HGSYATPHSQ 200
    RSVAQVCVDL PADTQGFAIQ ELIGLCEQAL ATPVQAAVRR PDEQAFARLN 250
    GANLMYVEDA ARRLRKQLAE HYATFHVAVR HLESLHAHDA VAETGSDDET 300
    FFPAAL 306
    Length:306
    Mass (Da):33,383
    Last modified:May 5, 2009 - v2
    Checksum:i7F85C6A280357FCF
    GO

    Sequence cautioni

    The sequence ACD58798.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000967 Genomic DNA. Translation: ACD58798.1. Different initiation.
    RefSeqiYP_001913330.1. NC_010717.1.

    Genome annotation databases

    EnsemblBacteriaiACD58798; ACD58798; PXO_00695.
    GeneIDi6305695.
    KEGGixop:PXO_00695.
    PATRICi24123758. VBIXanOry73153_2242.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000967 Genomic DNA. Translation: ACD58798.1 . Different initiation.
    RefSeqi YP_001913330.1. NC_010717.1.

    3D structure databases

    ProteinModelPortali B2SJL4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 360094.PXO_00695.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACD58798 ; ACD58798 ; PXO_00695 .
    GeneIDi 6305695.
    KEGGi xop:PXO_00695.
    PATRICi 24123758. VBIXanOry73153_2242.

    Phylogenomic databases

    eggNOGi COG1469.
    HOGENOMi HOG000247517.
    KOi K09007.
    OrthoDBi EOG6X6RBH.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .
    BioCyci XORY360094:GI45-2176-MONOMER.

    Family and domain databases

    HAMAPi MF_01527_B. GTP_cyclohydrol_B.
    InterProi IPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view ]
    Pfami PF02649. GCHY-1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PXO99A.

    Entry informationi

    Entry nameiGCH4_XANOP
    AccessioniPrimary (citable) accession number: B2SJL4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 5, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 47 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3