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B2SFN0 (GLGA_FRATM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:FTM_0572
OrganismFrancisella tularensis subsp. mediasiatica (strain FSC147) [Complete proteome] [HAMAP]
Taxonomic identifier441952 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella

Protein attributes

Sequence length489 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 489489Glycogen synthase HAMAP-Rule MF_00484
PRO_1000126078

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
B2SFN0 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 34F83A32CE9D1689

FASTA48953,564
        10         20         30         40         50         60 
MRVLHVCSEL YPILKTGGLA DVTAALPPAL AGFGVDSRVL VPGFPAFINA IKDKQLLINI 

        70         80         90        100        110        120 
PSRFGAEEIN IFLAKISNTK IDIYVIDAPS LFARPGNPYA DSSNQAYADN YLRFALLGWV 

       130        140        150        160        170        180 
AARISEGLDA KWKPEIVHSH DWHAGLVPAY IKASELASGK KAVKTVFTVH NLAYQGLFPM 

       190        200        210        220        230        240 
SVFAELDLPG IFLSMNGLEF YGQVSFMKAG LYFADKITTV SPTYAKEIQI YEQGCGLEGL 

       250        260        270        280        290        300 
LADRHNDLYG VLNGVDPQIW NPKKDSLIAT NYSSTTVATG KAKCKLALQQ MMGLAEKEDA 

       310        320        330        340        350        360 
LLFGIVTRLT EQKGLNLLIE AIGEITSRGG QIVLLGSGDK ALEEVFLAAA KKYSKSIAVQ 

       370        380        390        400        410        420 
IGYDEEQAHR IIAGSDVIMV PSRFEPCGLT QLYGLTYGTL PLVHKVGGLA DTVIDSSLEN 

       430        440        450        460        470        480 
LADGTATGFV FDEFSVESLT LVIRRAFALY NRKTDWKKVR KTAMQQQVTW DSSAEKIYQI 


YKNLVRENN 

« Hide

References

[1]"Molecular evolutionary consequences of niche restriction in Francisella tularensis, a facultative intracellular pathogen."
Larsson P., Elfsmark D., Svensson K., Wikstroem P., Forsman M., Brettin T., Keim P., Johansson A.
PLoS Pathog. 5:E1000472-E1000472(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FSC147.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000915 Genomic DNA. Translation: ACD30573.1.
RefSeqYP_001891351.1. NC_010677.1.

3D structure databases

ProteinModelPortalB2SFN0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING441952.FTM_0572.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD30573; ACD30573; FTM_0572.
GeneID6291674.
KEGGftm:FTM_0572.
PATRIC17955613. VBIFraTul67519_0713.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294941.
KOK00703.
OMAVHCNDWQ.
OrthoDBEOG6JTC6Z.
ProtClustDBPRK00654.

Enzyme and pathway databases

BioCycFTUL441952:GIY0-571-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_FRATM
AccessionPrimary (citable) accession number: B2SFN0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways