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B2SC34

- GLK_BRUA1

UniProt

B2SC34 - GLK_BRUA1

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Protein

Glucokinase

Gene
glk, BAbS19_II09360
Organism
Brucella abortus (strain S19)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 236ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO430066:GHI6-2980-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:BAbS19_II09360
OrganismiBrucella abortus (strain S19)
Taxonomic identifieri430066 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002565: Chromosome 2

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 343343GlucokinaseUniRule annotationPRO_0000383560Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi430066.BAbS19_II09360.

Structurei

3D structure databases

ProteinModelPortaliB2SC34.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

B2SC34-1 [UniParc]FASTAAdd to Basket

« Hide

MQAIIDAEQS FKFPVLVGDI GGTNARFSIL VDSNAEPKEF PVLQTADYAT    50
IDEAIQHAIL DQTAIQPRSV ILAVAGPVDG DEIDLTNCDW VVRPKKMIAD 100
LGFEDVTVLN DFEAQALAVV SLEGHHMEQI GGKPEEAVAT RVVLGPGTGL 150
GVAGLFRTRH AWVPVPGEGG HIDIGPRTER DYQIFPHIER IEGRVTGEQI 200
LSGRGLRNLY LGICAADKIT PTLETPVDIT SAGLDGSNPQ AAETLDLFAT 250
YLGRLAGDLA LIFMAHGGVY LSGGIPVRIL SALKAGSFRA TFEDKAPHKA 300
IMRDIPVRVI TYQLAALTGL SAFARTPSRF EVSTEGRRWR MRR 343
Length:343
Mass (Da):37,073
Last modified:September 22, 2009 - v2
Checksum:i2EBE41BFFF67FEC0
GO

Sequence cautioni

The sequence AAC43672.1 differs from that shown. Reason: Erroneous initiation.
The sequence ACD74421.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U21919 Genomic DNA. Translation: AAC43672.1. Different initiation.
CP000888 Genomic DNA. Translation: ACD74421.1. Different initiation.
RefSeqiYP_001932867.1. NC_010740.1.

Genome annotation databases

EnsemblBacteriaiACD74421; ACD74421; BAbS19_II09360.
GeneIDi6325873.
KEGGibmc:BAbS19_II09360.
PATRICi17816478. VBIBruAbo38055_1034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U21919 Genomic DNA. Translation: AAC43672.1 . Different initiation.
CP000888 Genomic DNA. Translation: ACD74421.1 . Different initiation.
RefSeqi YP_001932867.1. NC_010740.1.

3D structure databases

ProteinModelPortali B2SC34.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 430066.BAbS19_II09360.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD74421 ; ACD74421 ; BAbS19_II09360 .
GeneIDi 6325873.
KEGGi bmc:BAbS19_II09360.
PATRICi 17816478. VBIBruAbo38055_1034.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci BABO430066:GHI6-2980-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of the glucokinase gene of Brucella abortus 19 and identification of three other genes."
    Essenberg R.C.
    J. Bacteriol. 177:6297-6300(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes."
    Crasta O.R., Folkerts O., Fei Z., Mane S.P., Evans C., Martino-Catt S., Bricker B., Yu G., Du L., Sobral B.W.
    PLoS ONE 3:E2193-E2193(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S19.

Entry informationi

Entry nameiGLK_BRUA1
AccessioniPrimary (citable) accession number: B2SC34
Secondary accession number(s): Q576R6, Q59171
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 22, 2009
Last modified: June 11, 2014
This is version 38 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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