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B2SAP7 (B2SAP7_BRUA1) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate 1-dehydrogenase HAMAP-Rule MF_00966

Short name=G6PD HAMAP-Rule MF_00966
EC=1.1.1.49 HAMAP-Rule MF_00966
Gene names
Name:zwf HAMAP-Rule MF_00966
Ordered Locus Names:BAbS19_II04350 EMBL ACD73934.1
OrganismBrucella abortus (strain S19) [Complete proteome] [HAMAP] EMBL ACD73934.1
Taxonomic identifier430066 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone By similarity. HAMAP-Rule MF_00966

Catalytic activity

D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH. RuleBase RU000497 HAMAP-Rule MF_00966

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3. RuleBase RU000497 HAMAP-Rule MF_00966

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497 HAMAP-Rule MF_00966

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2421Proton acceptor By similarity HAMAP-Rule MF_00966
Binding site511NADP By similarity HAMAP-Rule MF_00966
Binding site1501NADP By similarity HAMAP-Rule MF_00966
Binding site1801Substrate By similarity HAMAP-Rule MF_00966
Binding site1841Substrate By similarity HAMAP-Rule MF_00966
Binding site2181Substrate By similarity HAMAP-Rule MF_00966
Binding site2371Substrate By similarity HAMAP-Rule MF_00966
Binding site3411Substrate By similarity HAMAP-Rule MF_00966

Sequences

Sequence LengthMass (Da)Tools
B2SAP7 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 9DD52902E2398ADA

FASTA49155,065
        10         20         30         40         50         60 
MTSQTIPVDP FDCIVFGGTG DLAERKLIPA LYQRQRAGQL SDPTRIIGAS RSQMTDDEYR 

        70         80         90        100        110        120 
TFAGNAIKEH VKPEEVDQAE VEIFLKRLHY VAVDAKSDEG WDALKTLIGK KPEKIRAFYL 

       130        140        150        160        170        180 
AVSPTLFGDI ATRLKAHGLI TRDTRIVVEK PIGRDLDSAK ALNDTLGSVF REDQIFRIDH 

       190        200        210        220        230        240 
YLGKETVQNL MALRFANALY EPLWNSAHID HVQITVAEAV GLEGRAGYYD KAGALRDMVQ 

       250        260        270        280        290        300 
NHILQLLCLV AMEPPSSIEA DAVHDEKVKV LRSLQPISTH NVEELTVRGQ YRAGASAGGP 

       310        320        330        340        350        360 
VKGYLEDLES DTSNTETFVA LKAEIANWRW AGVPFYLRTG KRLATRVSEI VVTFKPIPHS 

       370        380        390        400        410        420 
IFGESAGKVI ANQLVIRLQP DEGVKQWLMI KDPGPGGMRL RHMPLDMSFA ESFEDRNPDA 

       430        440        450        460        470        480 
YERLIMDVVR GNQTLFMRRD EVEAAWRWID PILQAWEFNS QPVQGYTAGT WGPSSSIALI 

       490 
ERDGRTWHES L 

« Hide

References

[1]"Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes."
Crasta O.R., Folkerts O., Fei Z., Mane S.P., Evans C., Martino-Catt S., Bricker B., Yu G., Du L., Sobral B.W.
PLoS ONE 3:E2193-E2193(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: S19 EMBL ACD73934.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000888 Genomic DNA. Translation: ACD73934.1.
RefSeqYP_001932380.1. NC_010740.1.

3D structure databases

ProteinModelPortalB2SAP7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING430066.BAbS19_II04350.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD73934; ACD73934; BAbS19_II04350.
GeneID6326255.
KEGGbmc:BAbS19_II04350.
PATRIC17815352. VBIBruAbo38055_0481.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0364.
HOGENOMHOG000046192.
KOK00036.
OMADSIMEAW.
OrthoDBEOG61308Z.

Enzyme and pathway databases

BioCycBABO430066:GHI6-2479-MONOMER.
UniPathwayUPA00115; UER00408.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_00966. G6PD.
InterProIPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR23429. PTHR23429. 1 hit.
PfamPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFPIRSF000110. G6PD. 1 hit.
PRINTSPR00079. G6PDHDRGNASE.
TIGRFAMsTIGR00871. zwf. 1 hit.
PROSITEPS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROB2SAP7.

Entry information

Entry nameB2SAP7_BRUA1
AccessionPrimary (citable) accession number: B2SAP7
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)