B2SA00 (ALLA_BRUA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	BAbS19_I04950

Organism

Brucella abortus (strain S19) [Complete proteome] [HAMAP]

Taxonomic identifier

430066 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616
Subunit structure	Homodimer By similarity. HAMAP MF_00616
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: InterPro purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Ureidoglycolate hydrolase HAMAP MF_00616		PRO_1000130410

Sequences

	Sequence		Length	Mass (Da)
	B2SA00 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 9D42DFA9E69C3EDB	FASTA	169	19,043
	10 20 30 40 50 60 MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARMEAA GTQTRVLINI 70 80 90 100 110 120 FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED AGAGPARPRA FLARGDQGVN 130 140 150 160 YLRNIWHHPL LALEQKSDFL VVDRAGREDN LEEYFFSDYA YRIETTQTA

References

[1]

"Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes." Crasta O.R., Folkerts O., Fei Z., Mane S.P., Evans C., Martino-Catt S., Bricker B., Yu G., Du L., Sobral B.W. PLoS ONE 3:E2193-E2193(2008) [PubMed: 18478107] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S19.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000887 Genomic DNA. Translation: ACD72030.1.
RefSeq	YP_001934504.1. NC_010742.1.
3D structure databases
ProteinModelPortal	B2SA00.
SMR	B2SA00. Positions 4-159.
ModBase	Search...
Protein-protein interaction databases
STRING	B2SA00.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6327656.
GenomeReviews	Gene locus BAbS19_I04950 in contig CP000887_GR.
KEGG	bmc:BAbS19_I04950.
PATRIC	17817962. VBIBruAbo38055_1757.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289179.
OMA	SQAFIPM.
ProtClustDB	PRK03606.
Family and domain databases
HAMAP	MF_00616. Ureidogly_hydro. [Tree]
InterPro	IPR011051. Cupin_RmlC_type. IPR007247. Ureidogly_hydro. IPR023525. Ureidogly_hydro_bac. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
Gene3D	G3DSA:2.60.120.480. G3DSA:2.60.120.480. 1 hit.
KO	K01483.
PANTHER	PTHR21221. Ureidogly_hydro. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_BRUA1

Accession

Primary (citable) accession number: B2SA00

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program