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B2S9A6

- TRPF_BRUA1

UniProt

B2S9A6 - TRPF_BRUA1

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Brucella abortus (strain S19)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (01 Jul 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciBABO430066:GHI6-1985-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
    Short name:
    PRAIUniRule annotation
    Gene namesi
    Name:trpFUniRule annotation
    Ordered Locus Names:BAbS19_I19760
    OrganismiBrucella abortus (strain S19)
    Taxonomic identifieri430066 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002565: Chromosome 1

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 222222N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000095914Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi430066.BAbS19_I19760.

    Structurei

    3D structure databases

    ProteinModelPortaliB2S9A6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0135.
    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiDILQLHG.
    OrthoDBiEOG6N94DF.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B2S9A6-1 [UniParc]FASTAAdd to Basket

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    MALDIKICGL KTPEAVAAAL DGGATHIGFI FFPKSPRHIT PDAAARLRAA    50
    ATGRAVAVAV TVDADDEALD EIVKTVRPDM LQLHGGETPE RVRFLKERYN 100
    LPVMKAFSIR EAGDLEAIAP YRGIADRFLF DAKPPKGSEL PGGNGISFDW 150
    NLLAALDADI DYMLSGGLNA DNIAEALLKT GAPGIDISSG VECAPGEKDV 200
    RLIENFFQAV ADANAQPFAR RA 222
    Length:222
    Mass (Da):23,614
    Last modified:July 1, 2008 - v1
    Checksum:i28E7AFA3258F5514
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000887 Genomic DNA. Translation: ACD73458.1.
    RefSeqiYP_001935932.1. NC_010742.1.

    Genome annotation databases

    EnsemblBacteriaiACD73458; ACD73458; BAbS19_I19760.
    GeneIDi6327080.
    KEGGibmc:BAbS19_I19760.
    PATRICi17821354. VBIBruAbo38055_3403.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000887 Genomic DNA. Translation: ACD73458.1 .
    RefSeqi YP_001935932.1. NC_010742.1.

    3D structure databases

    ProteinModelPortali B2S9A6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 430066.BAbS19_I19760.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACD73458 ; ACD73458 ; BAbS19_I19760 .
    GeneIDi 6327080.
    KEGGi bmc:BAbS19_I19760.
    PATRICi 17821354. VBIBruAbo38055_3403.

    Phylogenomic databases

    eggNOGi COG0135.
    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi DILQLHG.
    OrthoDBi EOG6N94DF.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci BABO430066:GHI6-1985-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes."
      Crasta O.R., Folkerts O., Fei Z., Mane S.P., Evans C., Martino-Catt S., Bricker B., Yu G., Du L., Sobral B.W.
      PLoS ONE 3:E2193-E2193(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S19.

    Entry informationi

    Entry nameiTRPF_BRUA1
    AccessioniPrimary (citable) accession number: B2S9A6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: July 1, 2008
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3