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B2S8P4 (B2S8P4_BRUA1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase HAMAP MF_01023
Gene names
Name:hisC HAMAP MF_01023
Ordered Locus Names:BAbS19_I18660
OrganismBrucella abortus (strain S19) [Complete proteome] [HAMAP]
Taxonomic identifier430066 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2261N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

Sequence LengthMass (Da)Tools
B2S8P4 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 8AD74BE03B39D6B9

FASTA36840,314
        10         20         30         40         50         60 
MTDMQKPTRP QPKAGVLDIA AYVPGKEHVE GVAKVYKLSS NETPLGPSPH AREAYRHAGE 

        70         80         90        100        110        120 
KLELYPDGQA LALRQAIAET QGLNISNILC GNGSDELLGL LCQTYLAPGD ETIITEHGFA 

       130        140        150        160        170        180 
VYKIQTLAAG ATPVTVKEKN ERIDVDAILA GVTARTKIVF IANPANPTGT YLPFEEVRRL 

       190        200        210        220        230        240 
HAGLPQHVLL VLDAAYAEYV RRNDYEAGLE LVSSNENVVM TRTFSKIHGL PGLRIGWIYA 

       250        260        270        280        290        300 
PLHIIDAMNR IRGPFNMNSA AIAAGAAAIR DRAHVEKSVA YNEKWLAWLT EEFTRLGLRV 

       310        320        330        340        350        360 
TPSVTNFLLI HFPDDAAHSA DKADEWLSRR GYILRRVGGY GFPNALRMTV GPEEANRGVV 


AALTEFLK

« Hide

References

[1]"Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes."
Crasta O.R., Folkerts O., Fei Z., Mane S.P., Evans C., Martino-Catt S., Bricker B., Yu G., Du L., Sobral B.W.
PLoS ONE 3:E2193-E2193(2008) [PubMed: 18478107] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000887 Genomic DNA. Translation: ACD73348.1.
RefSeqYP_001935822.1. NC_010742.1.

3D structure databases

ProteinModelPortalB2S8P4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2S8P4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6326967.
GenomeReviewsGene locus BAbS19_I18660 in contig CP000887_GR.
KEGGbmc:BAbS19_I18660.
PATRIC17821092. VBIBruAbo38055_3275.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646350.
OMAGFLVYRI.
ProtClustDBPRK02731.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001176. ACC_synthase.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSPR00753. ACCSYNTHASE.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2S8P4_BRUA1
AccessionPrimary (citable) accession number: B2S8P4
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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