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B2S8G4

- RNPH_BRUA1

UniProt

B2S8G4 - RNPH_BRUA1

Protein

Ribonuclease PH

Gene

rph

Organism
Brucella abortus (strain S19)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (01 Jul 2008)
      Previous versions | rss
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    Functioni

    Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.UniRule annotation

    Catalytic activityi

    tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.UniRule annotation

    GO - Molecular functioni

    1. tRNA binding Source: InterPro
    2. tRNA nucleotidyltransferase activity Source: UniProtKB-EC
    3. tRNA-specific ribonuclease activity Source: InterPro

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciBABO430066:GHI6-161-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease PHUniRule annotation (EC:2.7.7.56UniRule annotation)
    Short name:
    RNase PHUniRule annotation
    Alternative name(s):
    tRNA nucleotidyltransferaseUniRule annotation
    Gene namesi
    Name:rphUniRule annotation
    Ordered Locus Names:BAbS19_I01630
    OrganismiBrucella abortus (strain S19)
    Taxonomic identifieri430066 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002565: Chromosome 1

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 238238Ribonuclease PHPRO_1000129324Add
    BLAST

    Proteomic databases

    PRIDEiB2S8G4.

    Interactioni

    Protein-protein interaction databases

    STRINGi430066.BAbS19_I01630.

    Structurei

    3D structure databases

    ProteinModelPortaliB2S8G4.
    SMRiB2S8G4. Positions 2-238.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RNase PH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0689.
    HOGENOMiHOG000229516.
    KOiK00989.
    OMAiICTAMVE.
    OrthoDBiEOG6CZQQP.

    Family and domain databases

    Gene3Di3.30.230.70. 1 hit.
    HAMAPiMF_00564. RNase_PH.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR027408. PNPase/RNase_PH_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR002381. RNase_PH_bac-type.
    IPR018336. RNase_PH_CS.
    [Graphical view]
    PfamiPF01138. RNase_PH. 1 hit.
    PF03725. RNase_PH_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    SSF55666. SSF55666. 1 hit.
    TIGRFAMsiTIGR01966. RNasePH. 1 hit.
    PROSITEiPS01277. RIBONUCLEASE_PH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2S8G4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRPSKRAADE MRAISFERGV SKHAEGSCLV KFGDTHVLCT ASLEEKVPGW    50
    MRNTGKGWVT AEYGMLPRST GERMRREAAA GKQGGRTQEI QRLIGRSLRA 100
    VVDMQALGEM QITVDCDVIQ ADGGTRTAAI TGGWVALHEC LRWMEARQMV 150
    RVEKVLKDHV AAISCGIYEG VPVLDLDYAE DSVAETDSNF VMTGKGGIVE 200
    IQGTAEGVPF SEEEFGALMK LARSGIDRLV SLQKMAVA 238
    Length:238
    Mass (Da):25,907
    Last modified:July 1, 2008 - v1
    Checksum:i70CAF4B8F47A8E9C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000887 Genomic DNA. Translation: ACD71717.1.
    RefSeqiYP_001934191.1. NC_010742.1.

    Genome annotation databases

    EnsemblBacteriaiACD71717; ACD71717; BAbS19_I01630.
    GeneIDi6328108.
    KEGGibmc:BAbS19_I01630.
    PATRICi17817207. VBIBruAbo38055_1386.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000887 Genomic DNA. Translation: ACD71717.1 .
    RefSeqi YP_001934191.1. NC_010742.1.

    3D structure databases

    ProteinModelPortali B2S8G4.
    SMRi B2S8G4. Positions 2-238.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 430066.BAbS19_I01630.

    Proteomic databases

    PRIDEi B2S8G4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACD71717 ; ACD71717 ; BAbS19_I01630 .
    GeneIDi 6328108.
    KEGGi bmc:BAbS19_I01630.
    PATRICi 17817207. VBIBruAbo38055_1386.

    Phylogenomic databases

    eggNOGi COG0689.
    HOGENOMi HOG000229516.
    KOi K00989.
    OMAi ICTAMVE.
    OrthoDBi EOG6CZQQP.

    Enzyme and pathway databases

    BioCyci BABO430066:GHI6-161-MONOMER.

    Family and domain databases

    Gene3Di 3.30.230.70. 1 hit.
    HAMAPi MF_00564. RNase_PH.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR027408. PNPase/RNase_PH_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR002381. RNase_PH_bac-type.
    IPR018336. RNase_PH_CS.
    [Graphical view ]
    Pfami PF01138. RNase_PH. 1 hit.
    PF03725. RNase_PH_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    SSF55666. SSF55666. 1 hit.
    TIGRFAMsi TIGR01966. RNasePH. 1 hit.
    PROSITEi PS01277. RIBONUCLEASE_PH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes."
      Crasta O.R., Folkerts O., Fei Z., Mane S.P., Evans C., Martino-Catt S., Bricker B., Yu G., Du L., Sobral B.W.
      PLoS ONE 3:E2193-E2193(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S19.

    Entry informationi

    Entry nameiRNPH_BRUA1
    AccessioniPrimary (citable) accession number: B2S8G4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: July 1, 2008
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3