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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Brucella abortus (strain S19)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi8Divalent metal cationUniRule annotation1
Metal bindingi9Divalent metal cationUniRule annotation1
Metal bindingi40Divalent metal cationUniRule annotation1
Metal bindingi92Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:BAbS19_I08450
OrganismiBrucella abortus (strain S19)
Taxonomic identifieri430066 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002565 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000919871 – 2555'-nucleotidase SurEAdd BLAST255

Interactioni

Protein-protein interaction databases

STRINGi430066.BAbS19_I08450.

Structurei

Secondary structure

1255
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 6Combined sources4
Helixi14 – 26Combined sources13
Beta strandi30 – 37Combined sources8
Beta strandi52 – 58Combined sources7
Beta strandi61 – 66Combined sources6
Helixi68 – 77Combined sources10
Beta strandi80 – 82Combined sources3
Beta strandi85 – 94Combined sources10
Helixi98 – 102Combined sources5
Helixi105 – 115Combined sources11
Beta strandi120 – 125Combined sources6
Beta strandi128 – 130Combined sources3
Beta strandi133 – 135Combined sources3
Helixi138 – 155Combined sources18
Beta strandi161 – 167Combined sources7
Helixi172 – 174Combined sources3
Beta strandi177 – 180Combined sources4
Beta strandi190 – 196Combined sources7
Beta strandi202 – 208Combined sources7
Helixi220 – 225Combined sources6
Beta strandi228 – 236Combined sources9
Helixi241 – 243Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4ZG5X-ray1.90A/C/D/G1-255[»]
ProteinModelPortaliB2S5B9.
SMRiB2S5B9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiDCVHIAL.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiView protein in InterPro
IPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
IPR036523. SurE-like_sf.
PfamiView protein in Pfam
PF01975. SurE. 1 hit.
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

B2S5B9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILLTNDDG IHAEGLAVLE RIARKLSDDV WVVAPETDQS GLAHSLTLLE
60 70 80 90 100
PLRLRQIDAR HFALRGTPTD CVIMGVRHVL PGAPDLVLSG VNSGANMADD
110 120 130 140 150
VTYSGTVAGA MEGTLLGVRA IALSQEYEYA GDRRIVPWET AEAHAPELIG
160 170 180 190 200
RLMEAGWPEG VLLNLNFPNC APEEVKGVRV TAQGKLSHDA RLDERRDGRG
210 220 230 240 250
FPYFWLHFGR GKAPVADDSD IAAIRSGCIS MTPLHLDLTA HKVRAELGAA

LGVEA
Length:255
Mass (Da):27,509
Last modified:July 1, 2008 - v1
Checksum:i1494C219789E17F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000887 Genomic DNA. Translation: ACD72366.1.
RefSeqiWP_002966786.1. NC_010742.1.

Genome annotation databases

EnsemblBacteriaiACD72366; ACD72366; BAbS19_I08450.
KEGGibmc:BAbS19_I08450.

Similar proteinsi

Entry informationi

Entry nameiSURE_BRUA1
AccessioniPrimary (citable) accession number: B2S5B9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: October 25, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families