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B2S5B0

- SYR_BRUA1

UniProt

B2S5B0 - SYR_BRUA1

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Brucella abortus (strain S19)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO430066:GHI6-828-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BAbS19_I08360
OrganismiBrucella abortus (strain S19)
Taxonomic identifieri430066 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002565: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 585585Arginine--tRNA ligasePRO_1000095339Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi430066.BAbS19_I08360.

Structurei

3D structure databases

ProteinModelPortaliB2S5B0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi131 – 14111"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiIRNTIND.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2S5B0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNIFADFDAR IKKTFQDIDL KPKDGGELDL SRIGVEPPRD ASHGDIATNA
60 70 80 90 100
AMVLSKAVGQ NPRELAARIA EALKADEDVE SVDVAGPGFI NLRLKASYWQ
110 120 130 140 150
RELLVMLNEG TDFGRSRLGA GKKVNVEYVS ANPTGPMHVG HCRGAVVGDV
160 170 180 190 200
LANLLKFAGY DVVKEYYIND AGAQIDVLAR SVMLRYREAL GESIGEIPAG
210 220 230 240 250
LYPGDYLVRV GQELAGEFGT KLLEMPEAEA LAIVKDRTID AMMAMIRADL
260 270 280 290 300
DALNVHHDVF YSERKLHVDH ARAIRNAIND LTLKGHVYKG KLPPPKGRLP
310 320 330 340 350
EDWEDREQTL FRSTEVGDDI DRPLMKSDGS FTYFAGDVTY FKDKYDRGFN
360 370 380 390 400
EMIYVLGADH GGYVKRLEAV ARAVSDGKAK LTVLLCQLVK LFRNGEPVRM
410 420 430 440 450
SKRAGEFITL RDVVDEVGRD PVRFMMLYRK NDAPLDFDFA KVTEQSKDNP
460 470 480 490 500
VFYVQYASAR CHSVFRQAAD QLGLVDLDRV AMGSHFEKLT DESEIALVRK
510 520 530 540 550
LAEYPRLIES AAIHQEPHRL AFYLYDLASS FHSQWNRGAE NPDLRFIKVN
560 570 580
DPDLSLARLG LVQVVSDVLT SGLTIIGADA PTEMR
Length:585
Mass (Da):65,186
Last modified:July 1, 2008 - v1
Checksum:i354143BD9F45FD56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000887 Genomic DNA. Translation: ACD72357.1.
RefSeqiYP_001934831.1. NC_010742.1.

Genome annotation databases

EnsemblBacteriaiACD72357; ACD72357; BAbS19_I08360.
GeneIDi6327997.
KEGGibmc:BAbS19_I08360.
PATRICi17818732. VBIBruAbo38055_2136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000887 Genomic DNA. Translation: ACD72357.1 .
RefSeqi YP_001934831.1. NC_010742.1.

3D structure databases

ProteinModelPortali B2S5B0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 430066.BAbS19_I08360.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD72357 ; ACD72357 ; BAbS19_I08360 .
GeneIDi 6327997.
KEGGi bmc:BAbS19_I08360.
PATRICi 17818732. VBIBruAbo38055_2136.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi IRNTIND.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci BABO430066:GHI6-828-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes."
    Crasta O.R., Folkerts O., Fei Z., Mane S.P., Evans C., Martino-Catt S., Bricker B., Yu G., Du L., Sobral B.W.
    PLoS ONE 3:E2193-E2193(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S19.

Entry informationi

Entry nameiSYR_BRUA1
AccessioniPrimary (citable) accession number: B2S5B0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: October 29, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3