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B2S469

- SYR_TREPS

UniProt

B2S469 - SYR_TREPS

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Protein

Arginine--tRNA ligase

Gene
argS, TPASS_0831
Organism
Treponema pallidum subsp. pallidum (strain SS14)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAL455434:GJ9E-873-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:TPASS_0831
OrganismiTreponema pallidum subsp. pallidum (strain SS14)
Taxonomic identifieri455434 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000001202: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 589589Arginine--tRNA ligaseUniRule annotationPRO_1000095417Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi455434.TPASS_0831.

Structurei

3D structure databases

ProteinModelPortaliB2S469.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi132 – 14211"HIGH" regionUniRule annotationAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247211.
KOiK01887.
OMAiMEHMGFG.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2S469-1 [UniParc]FASTAAdd to Basket

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MQDLCEMWRH AVARVLSQLQ GPAVEPVEGA QLVMEEPPEP GMGDIAFPLF    50
LFAKRVRRSP AQLAQQLCTL LEEDTSMCAY GTPQARGPYL NVFLNKECVA 100
AHTLDAIFAQ GERYGHTQYL QGKRIMVEFS SPNTNKPLHV GHLRNNAIGE 150
SLSRIIAFCG ADVFKVNIIN DRGVHICKSM CAYQKFAHGK TPAHTGIKSD 200
RFVGDWYVQF NRYAQQYPEE AEHDVRDLLQ RWESADPHVR ALWRTMNEWA 250
LRGIKQTYER TGISFDKLYF ESETYTKGRE EVRRGLACGV FYQMEDNSIW 300
VDLSSLGLDK KALLRSDGTT MYITQDIGTA IFRAQDWPFD QLLYVVGNEQ 350
NYHFKVLFFV LRLLGYPWAQ QLHHVSYGMV NLPHGRMKSR EGTVVDADDI 400
LDRLHSAAEE EIAKKGRENA LKHAQCIAEN VAIAALHYFL LQVSPQKDMV 450
FHPEESLSFN GNTGPYLQYM GARISSLLKK VQEDVEQKGP REVRCDPALL 500
THEAEWELVK ALARFPACVT RAAQGHDPSV ITGYLYTLSK SFSRFYHDCP 550
ILCEARPDYA CARLELVRAV RIVLRTAMRL VLIPFLEEM 589
Length:589
Mass (Da):67,132
Last modified:July 1, 2008 - v1
Checksum:iFA6156A69F4568E3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000805 Genomic DNA. Translation: ACD71248.1.
RefSeqiYP_001933827.1. NC_010741.1.
YP_008119554.1. NC_021508.1.

Genome annotation databases

EnsemblBacteriaiACD71248; ACD71248; TPASS_0831.
GeneIDi15843693.
6332947.
KEGGitpp:TPASS_0831.
PATRICi20529463. VBITrePal10923_0880.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000805 Genomic DNA. Translation: ACD71248.1 .
RefSeqi YP_001933827.1. NC_010741.1.
YP_008119554.1. NC_021508.1.

3D structure databases

ProteinModelPortali B2S469.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 455434.TPASS_0831.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD71248 ; ACD71248 ; TPASS_0831 .
GeneIDi 15843693.
6332947.
KEGGi tpp:TPASS_0831.
PATRICi 20529463. VBITrePal10923_0880.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247211.
KOi K01887.
OMAi MEHMGFG.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci TPAL455434:GJ9E-873-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Treponema pallidum ssp. pallidum strain SS14 determined with oligonucleotide arrays."
    Matejkova P., Strouhal M., Smajs D., Norris S.J., Palzkill T., Petrosino J.F., Sodergren E., Norton J.E., Singh J., Richmond T.A., Molla M.N., Albert T.J., Weinstock G.M.
    BMC Microbiol. 8:76-76(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SS14.

Entry informationi

Entry nameiSYR_TREPS
AccessioniPrimary (citable) accession number: B2S469
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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