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B2S1P1

- PGK_BORHD

UniProt

B2S1P1 - PGK_BORHD

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Protein

Phosphoglycerate kinase

Gene
pgk, BH0056
Organism
Borrelia hermsii (strain HS1 / DAH)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei118 – 1181Substrate By similarity
Binding sitei151 – 1511Substrate By similarity
Binding sitei201 – 2011ATP By similarity
Binding sitei292 – 2921ATP; via carbonyl oxygen By similarity
Binding sitei323 – 3231ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi349 – 3524ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBHER314723:GJES-53-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:BH0056
OrganismiBorrelia hermsii (strain HS1 / DAH)
Taxonomic identifieri314723 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorrelia
ProteomesiUP000008834: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 392392Phosphoglycerate kinaseUniRule annotationPRO_1000192807Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi314723.BH0056.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiFNVPLRE.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

B2S1P1-1 [UniParc]FASTAAdd to Basket

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MSIKTIKDFD FSGKRALVRC DFNVPLREGN ITDDTRIRAA LPTIEYLKSQ    50
GARVVLMSHL GRPKGERNLK YSLMPVAKRL SELLGQDVKM LPDCIGDEVA 100
TAVSNMKNGD VVLLENIRFY RQEEENCNDF AKKLSQNGDI FVNDAFGTAH 150
RAHASTAGLA AYLPAVGGFL MEKEDEFLGK ILKNPESPFV SIIGGSKVSS 200
KIAVLESLLP KSNVMVIGGG MAYTFLKVEG HSIGKSLLEN EYIDVAASFL 250
KKAKELDVKV ILPLDHIVAS EFKEDSIPEY VDAIDIPDGK IGMDIGEKTL 300
RKIEEVLVSA KTVIWNGPLG VFEFDSFSKG TAKVAEYVAS CSGITVVGGG 350
DSVAAVNKFN LSEKITHVST GGGASLEYLE GKILPGIKVL EK 392
Length:392
Mass (Da):42,478
Last modified:July 1, 2008 - v1
Checksum:i1054E3BC6C6EB801
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000048 Genomic DNA. Translation: AAX16578.1.
RefSeqiYP_001883498.1. NC_010673.1.

Genome annotation databases

EnsemblBacteriaiAAX16578; AAX16578; BH0056.
GeneIDi6276622.
KEGGibhr:BH0056.
PATRICi20567430. VBIBorHer61105_0057.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000048 Genomic DNA. Translation: AAX16578.1 .
RefSeqi YP_001883498.1. NC_010673.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 314723.BH0056.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX16578 ; AAX16578 ; BH0056 .
GeneIDi 6276622.
KEGGi bhr:BH0056.
PATRICi 20567430. VBIBorHer61105_0057.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi FNVPLRE.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci BHER314723:GJES-53-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Borrelia hermsii and Borrelia turicatae: comparative analysis of two agents of endemic N. America relapsing fever."
    Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T., Schwan T.G.
    Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HS1 / DAH.

Entry informationi

Entry nameiPGK_BORHD
AccessioniPrimary (citable) accession number: B2S1P1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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