Reviewed, UniProtKB/Swiss-Prot B2S0W8 (ACKA_BORHD)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BH0622

Organism

Borrelia hermsii (strain DAH) [Complete proteome] [HAMAP]

Taxonomic identifier

314723 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 408	408	Acetate kinase HAMAP MF_00020		PRO_1000089961

Sequences

	Sequence		Length	Mass (Da)
	B2S0W8-1 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: AF54C65AD3084454	FASTA	408	46,076
	10 20 30 40 50 60 MKILTLNTGS SSLKFTLYQH KNTQILASGT IEKIKTKKSI IRIKTQNDLL EKIDKHIKSH 70 80 90 100 110 120 KEALKQLIKI LTNKKLNIIN NLNEIQGIGH RIVHGGPNFK NSVILNENIL SELEKISALA 130 140 150 160 170 180 PLHNPTAIKV IEITLKIFPN AKQVLCFDTS WHQTMNENAF LYATPYSWYK DYNIRKYGFH 190 200 210 220 230 240 GLSYAYITKR VATILNKHKK DLNLIILHLG NGSSINAVKK GISYDTSMGL TPLEGLAMGT 250 260 270 280 290 300 RSGDIDPAII PLMSKVLNKT PRKIEEILNK ESGMLGISLK SNDLRDIWEG VENNEYNSKL 310 320 330 340 350 360 AVEIMAYRIK KYIGSYLAIL EFNIDAIVFT AGIGVTDYGI RELSLKGFEK IGIEIDLQKN 370 380 390 400 NLAREKNIES DISSEKSKTK ILVIPTNEEL TILEDTYNLI TEHSRDLK

References

[1]

"The genome sequence of Borrelia hermsii and Borrelia turicatae: comparative analysis of two agents of endemic N. America relapsing fever." Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T., Schwan T.G. Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000048 Genomic DNA. Translation: AAX17124.1.
RefSeq	YP_001884044.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6277108.
GenomeReviews	Gene locus BH0622 in contig CP000048_GR.
KEGG	bhr:BH0622.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CFDTSWH.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BORHD

Accession

Primary (citable) accession number: B2S0W8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 1, 2008
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)