B2S022 (B2S022_BORHD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase HAMAP-Rule MF_00361
Short name=Poly(P)/ATP NAD kinase HAMAP-Rule MF_00361
EC=2.7.1.23 HAMAP-Rule MF_00361

Gene names

Name:	ppnK HAMAP-Rule MF_00361
Ordered Locus Names:	BH0311

Organism

Borrelia hermsii (strain DAH) [Complete proteome] [HAMAP] EMBL AAX16828.1

Taxonomic identifier

314723 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia hermsii

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361 SAAS SAAS016064
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361 SAAS SAAS016064
Cofactor	Divalent metal ions By similarity. HAMAP-Rule MF_00361 SAAS SAAS016064
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00361 SAAS SAAS016064.
Sequence similarities	Belongs to the NAD kinase family. HAMAP-Rule MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00361 SAAS SAAS016064
Ligand	ATP-binding HAMAP-Rule MF_00361 SAAS SAAS016064 NAD HAMAP-Rule MF_00361 SAAS SAAS016064 NADP HAMAP-Rule MF_00361 SAAS SAAS016064 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00361 SAAS SAAS016064 EMBL AAX16828.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	NAD metabolic process Inferred from electronic annotation. Source: InterPro NADP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2S022 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 46FACB6B93DB8949	FASTA	292	32,302
	10 20 30 40 50 60 MTRVNLKGFH IRRAMKSKVL IYVNYSNSDA EVLACEIQKY LEHKYGVLSL FAGINKSSEV 70 80 90 100 110 120 LTEADLIFAI TLGGDGTVLL ASGLLLKNDI DIPIISINLG KVGFLADIKP RDFKEVIDKF 130 140 150 160 170 180 FNNSLFIHKK YLLSISAYEN GNNIFTKYAL NDVIIRSSAL NKLIYVSLRV NSEDFLSYRS 190 200 210 220 230 240 DGIIFATPTG STGYSFSAGG AILESDLRAF ILTPISPHSV YNRSFIFSSG SKLSLSFQKG 250 260 270 280 290 YALNSASIFV DGVNIGTFGV DIVFELGLDN KSLRFASFCT DTFVRRLKNK LL

References

[1]

"The genome sequence of Borrelia hermsii and Borrelia turicatae: comparative analysis of two agents of endemic N. America relapsing fever." Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T., Schwan T.G. Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DAH.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000048 Genomic DNA. Translation: AAX16828.1.
RefSeq	YP_001883748.1. NC_010673.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	314723.BH0311.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAX16828; AAX16828; BH0311.
GeneID	6277226.
KEGG	bhr:BH0311.
PATRIC	20567948. VBIBorHer61105_0312.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG148743.
HOGENOM	HOG000103026.
KO	K00858.
OMA	FPRENFL.
ProtClustDB	CLSK507507.
Enzyme and pathway databases
BioCyc	BHER314723:GJES-307-MONOMER.
Family and domain databases
Gene3D	2.60.200.30. 1 hit. 3.40.50.10330. 1 hit.
HAMAP	MF_00361. NAD_kinase.
InterPro	IPR017438. ATP-NAD_kinase_dom_1. IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. PolyP/ATP_NADK_prd. [Graphical view]
PANTHER	PTHR20275. PTHR20275. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2S022_BORHD

Accession

Primary (citable) accession number: B2S022

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)