Reviewed, UniProtKB/Swiss-Prot B2RZJ4 (KCY_BORHD)

Names and origin

Protein names

Recommended name:
    Cytidylate kinase
      Short name=CK
    EC=2.7.4.14
Alternative name(s):
    Cytidine monophosphate kinase
      Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	BH0128

Organism

Borrelia hermsii (strain DAH) [Complete proteome] [HAMAP]

Taxonomic identifier

314723 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	Cytidylate kinase HAMAP MF_00238		PRO_1000100647
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B2RZJ4-1 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 2AE386DEF13335EA	FASTA	218	25,044
	10 20 30 40 50 60 MIIAIDGPSA SGKSSIAKAL GSRLGFKFIS SGYFYRIITL IAQKFTLNEY DLLSESKILE 70 80 90 100 110 120 LVLQNDIKFN GVDFLLNGVN VTSHILNERI DLQVSLYSSY IGVRNIVNKK LREIVKLKDD 130 140 150 160 170 180 NYIIEGRDIT TVVFPEAKVK IYLDASVKVR ALRRYNQRDD DITLNELEQA LERRDEIDQN 190 200 210 KEYGKLKLAK EVFYIDTSYK CLDDVCDIII KTFNLKKK

References

[1]

"The genome sequence of Borrelia hermsii and Borrelia turicatae: comparative analysis of two agents of endemic N. America relapsing fever." Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T., Schwan T.G. Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000048 Genomic DNA. Translation: AAX16650.1.
RefSeq	YP_001883570.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6276904.
GenomeReviews	Gene locus BH0128 in contig CP000048_GR.
KEGG	bhr:BH0128.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GLLYRAV.
Family and domain databases
HAMAP	MF_00238. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kin_d. [Graphical view]
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BORHD

Accession

Primary (citable) accession number: B2RZJ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 1, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)