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Protein

Cyclin-dependent kinases regulatory subunit

Gene

Cks1b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell divisionUniRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-187577. SCF(Skp2)-mediated degradation of p27/p21.
R-RNO-69231. Cyclin D associated events in G1.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunitUniRule annotation
Gene namesi
Name:Cks1bImported
Synonyms:Cks1lImported, RGD1561797Imported, RGD1561797_predictedImported
ORF Names:rCG_62723Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1561797. Cks1b.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSRNOG00000042561.

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3484. Eukaryota.
ENOG4111UAN. LUCA.
GeneTreeiENSGT00390000011006.
HOVERGENiHBG003626.
InParanoidiD4AD86.
KOiK02219.
OMAiLMTENEW.
OrthoDBiEOG091G18GQ.
TreeFamiTF101142.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiView protein in InterPro
IPR000789. Cyclin-dep_kinase_reg-sub.
PfamiView protein in Pfam
PF01111. CKS. 1 hit.
PRINTSiPR00296. CYCLINKINASE.
SMARTiView protein in SMART
SM01084. CKS. 1 hit.
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiView protein in PROSITE
PS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B2RZ99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ
60 70
SQGWVHYMIH EPEPHILLFR RPLPKKPKK
Length:79
Mass (Da):9,660
Last modified:July 1, 2008 - v1
Checksum:iE64207B140FA38D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098750 Genomic DNA. No translation available.
BC167077 mRNA. Translation: AAI67077.1.
BC168780 mRNA. Translation: AAI68780.1.
CH473976 Genomic DNA. Translation: EDM00630.1.
RefSeqiNP_001129221.1. NM_001135749.1.
UniGeneiRn.119060.

Genome annotation databases

EnsembliENSRNOT00000055533; ENSRNOP00000052395; ENSRNOG00000042561.
GeneIDi499655.
KEGGirno:499655.
UCSCiRGD:1561797. rat.

Similar proteinsi

Entry informationi

Entry nameiB2RZ99_RAT
AccessioniPrimary (citable) accession number: B2RZ99
Secondary accession number(s): D4AD86
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: August 30, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported