ID   MADL2_RAT               Reviewed;         307 AA.
AC   B2RZ87;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   24-JAN-2024, entry version 63.
DE   RecName: Full=Myeloid-associated differentiation marker-like protein 2;
GN   Name=Myadml2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MAL family. {ECO:0000305}.
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DR   EMBL; CH473948; EDM06879.1; -; Genomic_DNA.
DR   EMBL; BC167064; AAI67064.1; -; mRNA.
DR   RefSeq; NP_001121657.1; NM_001128185.1.
DR   AlphaFoldDB; B2RZ87; -.
DR   SMR; B2RZ87; -.
DR   STRING; 10116.ENSRNOP00000051831; -.
DR   PaxDb; 10116-ENSRNOP00000051831; -.
DR   Ensembl; ENSRNOT00000054948.4; ENSRNOP00000051831.2; ENSRNOG00000036681.4.
DR   Ensembl; ENSRNOT00055057191; ENSRNOP00055047169; ENSRNOG00055033089.
DR   Ensembl; ENSRNOT00060054518; ENSRNOP00060045107; ENSRNOG00060031456.
DR   Ensembl; ENSRNOT00065007638; ENSRNOP00065005303; ENSRNOG00065005196.
DR   GeneID; 303744; -.
DR   KEGG; rno:303744; -.
DR   AGR; RGD:1311499; -.
DR   CTD; 255275; -.
DR   RGD; 1311499; Myadml2.
DR   eggNOG; KOG4788; Eukaryota.
DR   GeneTree; ENSGT00950000182933; -.
DR   HOGENOM; CLU_068368_0_0_1; -.
DR   InParanoid; B2RZ87; -.
DR   OMA; HLSWGNF; -.
DR   OrthoDB; 3818412at2759; -.
DR   PhylomeDB; B2RZ87; -.
DR   PRO; PR:B2RZ87; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Proteomes; UP000234681; Chromosome 10.
DR   Bgee; ENSRNOG00000036681; Expressed in quadriceps femoris and 7 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR047123; MYADM-like.
DR   PANTHER; PTHR17068; MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER; 1.
DR   PANTHER; PTHR17068:SF5; MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2; 1.
DR   Pfam; PF01284; MARVEL; 2.
DR   PROSITE; PS51225; MARVEL; 2.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT   CHAIN           1..307
FT                   /note="Myeloid-associated differentiation marker-like
FT                   protein 2"
FT                   /id="PRO_0000357328"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        129..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        232..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          17..154
FT                   /note="MARVEL 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
FT   DOMAIN          159..303
FT                   /note="MARVEL 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
SQ   SEQUENCE   307 AA;  33165 MW;  5243171B0B919E6D CRC64;
     MGSTMEPPGG AYLHLGAVTS PVGTARMLQL AFGCTTFSLV AHRGGFGGVQ GTFCMAAWGF
     CFAFSVLVVA CEFTRLHSCL RLSWGNFTAA FAMLATLLCA TAAVIYPLYF TRLECPPEPA
     GCMVRNFRLA ASVFAGLLFL AYAAEVALTR ARPGQVASYM ATVSGLLKIV QAFVACIIFG
     ALVHESRYGR YVATQWCVAV YSLCFMATVA VVVLSVMGHT GGLGCPFDRL VVVYTFLAVL
     LYLSAAVIWP VFCFDPKYGE PGRPSDCPRG SCPWDSQLVV AIFTYVNLLL YIVDLAYSQR
     IRFVPTL
//