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B2RZ87 (MADL2_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Myeloid-associated differentiation marker-like protein 2
Gene names
Name:Myadml2
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the MAL family.

Contains 2 MARVEL domains.

Ontologies

Keywords
   Cellular componentMembrane
   DomainRepeat
Transmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Myeloid-associated differentiation marker-like protein 2
PRO_0000357328

Regions

Transmembrane53 – 7321Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane163 – 18321Helical; Potential
Transmembrane198 – 21821Helical; Potential
Transmembrane232 – 25221Helical; Potential
Transmembrane278 – 29821Helical; Potential
Domain17 – 154138MARVEL 1
Domain159 – 303145MARVEL 2

Sequences

Sequence LengthMass (Da)Tools
B2RZ87 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 5243171B0B919E6D

FASTA30733,165
        10         20         30         40         50         60 
MGSTMEPPGG AYLHLGAVTS PVGTARMLQL AFGCTTFSLV AHRGGFGGVQ GTFCMAAWGF 

        70         80         90        100        110        120 
CFAFSVLVVA CEFTRLHSCL RLSWGNFTAA FAMLATLLCA TAAVIYPLYF TRLECPPEPA 

       130        140        150        160        170        180 
GCMVRNFRLA ASVFAGLLFL AYAAEVALTR ARPGQVASYM ATVSGLLKIV QAFVACIIFG 

       190        200        210        220        230        240 
ALVHESRYGR YVATQWCVAV YSLCFMATVA VVVLSVMGHT GGLGCPFDRL VVVYTFLAVL 

       250        260        270        280        290        300 
LYLSAAVIWP VFCFDPKYGE PGRPSDCPRG SCPWDSQLVV AIFTYVNLLL YIVDLAYSQR 


IRFVPTL

« Hide

References

[1]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Heart.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CH473948 Genomic DNA. Translation: EDM06879.1.
BC167064 mRNA. Translation: AAI67064.1.
IPIIPI00896777.
RefSeqNP_001121657.1. NM_001128185.1.
UniGeneRn.204828.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000054948; ENSRNOP00000051831; ENSRNOG00000036681.
GeneID303744.
KEGGrno:303744.

Organism-specific databases

CTD255275.
RGD1311499. Myadml2.

Phylogenomic databases

eggNOGNOG291197.
GeneTreeENSGT00390000010832.
HOVERGENHBG052545.

Gene expression databases

GenevestigatorB2RZ87.

Family and domain databases

InterProIPR008253. Marvel.
IPR021128. MARVEL-like_dom.
[Graphical view]
PfamPF01284. MARVEL. 2 hits.
[Graphical view]
PROSITEPS51225. MARVEL. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio651997.

Entry information

Entry nameMADL2_RAT
AccessionPrimary (citable) accession number: B2RZ87
Entry history
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: July 1, 2008
Last modified: April 3, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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