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B2RZ87

- MADL2_RAT

UniProt

B2RZ87 - MADL2_RAT

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Protein

Myeloid-associated differentiation marker-like protein 2

Gene

Myadml2

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Myeloid-associated differentiation marker-like protein 2
Gene namesi
Name:Myadml2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 10

Organism-specific databases

RGDi1311499. Myadml2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei53 – 7321HelicalSequence AnalysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence AnalysisAdd
BLAST
Transmembranei129 – 14921HelicalSequence AnalysisAdd
BLAST
Transmembranei163 – 18321HelicalSequence AnalysisAdd
BLAST
Transmembranei198 – 21821HelicalSequence AnalysisAdd
BLAST
Transmembranei232 – 25221HelicalSequence AnalysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Myeloid-associated differentiation marker-like protein 2PRO_0000357328Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriB2RZ87.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 154138MARVEL 1PROSITE-ProRule annotationAdd
BLAST
Domaini159 – 303145MARVEL 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the MAL family.Curated
Contains 2 MARVEL domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG291197.
GeneTreeiENSGT00390000010832.
HOVERGENiHBG052545.
InParanoidiB2RZ87.
OMAiVATQWCV.
OrthoDBiEOG73JKVX.
PhylomeDBiB2RZ87.

Family and domain databases

InterProiIPR008253. Marvel.
[Graphical view]
PfamiPF01284. MARVEL. 2 hits.
[Graphical view]
PROSITEiPS51225. MARVEL. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RZ87-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MGSTMEPPGG AYLHLGAVTS PVGTARMLQL AFGCTTFSLV AHRGGFGGVQ
60 70 80 90 100
GTFCMAAWGF CFAFSVLVVA CEFTRLHSCL RLSWGNFTAA FAMLATLLCA
110 120 130 140 150
TAAVIYPLYF TRLECPPEPA GCMVRNFRLA ASVFAGLLFL AYAAEVALTR
160 170 180 190 200
ARPGQVASYM ATVSGLLKIV QAFVACIIFG ALVHESRYGR YVATQWCVAV
210 220 230 240 250
YSLCFMATVA VVVLSVMGHT GGLGCPFDRL VVVYTFLAVL LYLSAAVIWP
260 270 280 290 300
VFCFDPKYGE PGRPSDCPRG SCPWDSQLVV AIFTYVNLLL YIVDLAYSQR

IRFVPTL
Length:307
Mass (Da):33,165
Last modified:July 1, 2008 - v1
Checksum:i5243171B0B919E6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473948 Genomic DNA. Translation: EDM06879.1.
BC167064 mRNA. Translation: AAI67064.1.
RefSeqiNP_001121657.1. NM_001128185.1.
UniGeneiRn.204828.

Genome annotation databases

EnsembliENSRNOT00000054948; ENSRNOP00000051831; ENSRNOG00000036681.
GeneIDi303744.
KEGGirno:303744.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473948 Genomic DNA. Translation: EDM06879.1 .
BC167064 mRNA. Translation: AAI67064.1 .
RefSeqi NP_001121657.1. NM_001128185.1.
UniGenei Rn.204828.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000054948 ; ENSRNOP00000051831 ; ENSRNOG00000036681 .
GeneIDi 303744.
KEGGi rno:303744.

Organism-specific databases

CTDi 255275.
RGDi 1311499. Myadml2.

Phylogenomic databases

eggNOGi NOG291197.
GeneTreei ENSGT00390000010832.
HOVERGENi HBG052545.
InParanoidi B2RZ87.
OMAi VATQWCV.
OrthoDBi EOG73JKVX.
PhylomeDBi B2RZ87.

Miscellaneous databases

NextBioi 651997.

Gene expression databases

Genevestigatori B2RZ87.

Family and domain databases

InterProi IPR008253. Marvel.
[Graphical view ]
Pfami PF01284. MARVEL. 2 hits.
[Graphical view ]
PROSITEi PS51225. MARVEL. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart.

Entry informationi

Entry nameiMADL2_RAT
AccessioniPrimary (citable) accession number: B2RZ87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: July 1, 2008
Last modified: October 29, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3