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Protein

Myeloid-associated differentiation marker-like protein 2

Gene

Myadml2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Myeloid-associated differentiation marker-like protein 2
Gene namesi
Name:Myadml2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1311499. Myadml2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei53 – 7321HelicalSequence AnalysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence AnalysisAdd
BLAST
Transmembranei129 – 14921HelicalSequence AnalysisAdd
BLAST
Transmembranei163 – 18321HelicalSequence AnalysisAdd
BLAST
Transmembranei198 – 21821HelicalSequence AnalysisAdd
BLAST
Transmembranei232 – 25221HelicalSequence AnalysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Myeloid-associated differentiation marker-like protein 2PRO_0000357328Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000051831.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 154138MARVEL 1PROSITE-ProRule annotationAdd
BLAST
Domaini159 – 303145MARVEL 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the MAL family.Curated
Contains 2 MARVEL domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG291197.
GeneTreeiENSGT00390000010832.
HOVERGENiHBG052545.
InParanoidiB2RZ87.
OMAiVATQWCV.
OrthoDBiEOG73JKVX.
PhylomeDBiB2RZ87.

Family and domain databases

InterProiIPR008253. Marvel.
[Graphical view]
PfamiPF01284. MARVEL. 2 hits.
[Graphical view]
PROSITEiPS51225. MARVEL. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RZ87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSTMEPPGG AYLHLGAVTS PVGTARMLQL AFGCTTFSLV AHRGGFGGVQ
60 70 80 90 100
GTFCMAAWGF CFAFSVLVVA CEFTRLHSCL RLSWGNFTAA FAMLATLLCA
110 120 130 140 150
TAAVIYPLYF TRLECPPEPA GCMVRNFRLA ASVFAGLLFL AYAAEVALTR
160 170 180 190 200
ARPGQVASYM ATVSGLLKIV QAFVACIIFG ALVHESRYGR YVATQWCVAV
210 220 230 240 250
YSLCFMATVA VVVLSVMGHT GGLGCPFDRL VVVYTFLAVL LYLSAAVIWP
260 270 280 290 300
VFCFDPKYGE PGRPSDCPRG SCPWDSQLVV AIFTYVNLLL YIVDLAYSQR

IRFVPTL
Length:307
Mass (Da):33,165
Last modified:July 1, 2008 - v1
Checksum:i5243171B0B919E6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473948 Genomic DNA. Translation: EDM06879.1.
BC167064 mRNA. Translation: AAI67064.1.
RefSeqiNP_001121657.1. NM_001128185.1.
UniGeneiRn.204828.

Genome annotation databases

EnsembliENSRNOT00000054948; ENSRNOP00000051831; ENSRNOG00000036681.
GeneIDi303744.
KEGGirno:303744.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473948 Genomic DNA. Translation: EDM06879.1.
BC167064 mRNA. Translation: AAI67064.1.
RefSeqiNP_001121657.1. NM_001128185.1.
UniGeneiRn.204828.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000051831.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000054948; ENSRNOP00000051831; ENSRNOG00000036681.
GeneIDi303744.
KEGGirno:303744.

Organism-specific databases

CTDi255275.
RGDi1311499. Myadml2.

Phylogenomic databases

eggNOGiNOG291197.
GeneTreeiENSGT00390000010832.
HOVERGENiHBG052545.
InParanoidiB2RZ87.
OMAiVATQWCV.
OrthoDBiEOG73JKVX.
PhylomeDBiB2RZ87.

Miscellaneous databases

NextBioi651997.
PROiB2RZ87.

Family and domain databases

InterProiIPR008253. Marvel.
[Graphical view]
PfamiPF01284. MARVEL. 2 hits.
[Graphical view]
PROSITEiPS51225. MARVEL. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart.

Entry informationi

Entry nameiMADL2_RAT
AccessioniPrimary (citable) accession number: B2RZ87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: July 1, 2008
Last modified: June 24, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.