B2RZ33 (B2RZ33_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nck1 protein EMBL AAI67009.1

Submitted name:
Non-catalytic region of tyrosine kinase adaptor protein 1 (Predicted), isoform CRA_a EMBL EDL77422.1

Gene names

Name:	Nck1 RGD 1310688
Synonyms:	Nck1_predicted EMBL EDL77422.1
ORF Names:	rCG_25905 EMBL EDL77422.1

Organism

Rattus norvegicus (Rat) EMBL AAI67009.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 3 SH3 domains. RuleBase RU003338

Ontologies

Keywords
Domain	SH3 domain SAAS SAAS000980 RuleBase RU003338
Molecular function	Kinase EMBL EDL77422.1 Transferase
Gene Ontology (GO)
Molecular function	kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2RZ33 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 6D28AD5870A89C29	FASTA	377	42,877
	10 20 30 40 50 60 MAEEVVVVAK FDYVAQQEQE LDIKKNERLW LLDDSKSWWR VRNSMNKTGF VPSNYVERKN 70 80 90 100 110 120 SARKASIVKN LKDTLGIGKV KRKPSVPDTA SPADDSFVDP GERLYDLNMP AFVKFNYMAE 130 140 150 160 170 180 REDELSLIKG TKVIVMEKCS DGWWRGSYNG QIGWFPSNYV TEEGDSPLGD HVGSLSEKLA 190 200 210 220 230 240 AVVNNLNTGQ VLHVVQALYP FSSSNDEELN FEKGDVMDVI EKPENDPEWW KCRKINGMVG 250 260 270 280 290 300 LVPKNYVTVM QNNPLTSGLE PSPPQCDYIR PSLTGKFAGN PWYYGKVTRH QAEMALNERG 310 320 330 340 350 360 HEGDFLIRDS ESSPNDFSVS LKAQGKNKHF KVQLKETVYC IGQRKFSTME ELVEHYKKAP 370 IFTSEQGEKL YLVKHLS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Heart EMBL AAI67009.1.
[2]	"Gene and alternative splicing annotation with AIR." Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G. Genome Res. 15:54-66(2005) [PubMed: 15632090] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL77422.1.
[3]	Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL77422.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC167009 mRNA. Translation: AAI67009.1. CH473954 Genomic DNA. Translation: EDL77422.1. CH473954 Genomic DNA. Translation: EDL77423.1. CH473954 Genomic DNA. Translation: EDL77424.1.
IPI	IPI00765594.
RefSeq	NP_001100321.1. NM_001106851.2.
UniGene	Rn.8768.
3D structure databases
ProteinModelPortal	B2RZ33.
SMR	B2RZ33. Positions 1-61, 99-174, 190-254, 279-377.
ModBase	Search...
Protein-protein interaction databases
STRING	B2RZ33.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	300955.
KEGG	rno:300955.
Organism-specific databases
CTD	4690.
RGD	1310688. Nck1.
Phylogenomic databases
eggNOG	roNOG08154.
GeneTree	ENSGT00550000074482.
HOVERGEN	HBG000719.
OrthoDB	EOG40ZQXR.
Gene expression databases
Genevestigator	B2RZ33.
Family and domain databases
InterPro	IPR017304. Cytoplasmic_NCK. IPR000980. SH2. IPR001452. SH3_domain. [Graphical view]
Gene3D	G3DSA:3.30.505.10. SH2. 1 hit.
KO	K07365.
Pfam	PF00017. SH2. 1 hit. PF00018. SH3_1. 3 hits. [Graphical view]
PIRSF	PIRSF037874. Cytoplasmic_NCK. 1 hit.
PRINTS	PR00401. SH2DOMAIN. PR00452. SH3DOMAIN.
SMART	SM00252. SH2. 1 hit. SM00326. SH3. 3 hits. [Graphical view]
SUPFAM	SSF50044. SH3. 3 hits.
PROSITE	PS50001. SH2. 1 hit. PS50002. SH3. 3 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	647786.

Entry information

Entry name

B2RZ33_RAT

Accession

Primary (citable) accession number: B2RZ33

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	November 16, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)