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Protein
Submitted name:

Ppfia1 protein

Gene

Ppfia1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. negative regulation of establishment of protein localization to plasma membrane Source: MGI
  2. negative regulation of stress fiber assembly Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_205038. Acetylcholine Neurotransmitter Release Cycle.
REACT_229514. Glutamate Neurotransmitter Release Cycle.
REACT_242222. Norepinephrine Neurotransmitter Release Cycle.

Names & Taxonomyi

Protein namesi
Submitted name:
Ppfia1 proteinImported
Submitted name:
Protein Ppfia1Imported
Gene namesi
Name:Ppfia1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:1924750. Ppfia1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. focal adhesion Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriB2RXQ2.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG261376.
GeneTreeiENSGT00760000119138.
HOVERGENiHBG052330.
OMAiNEIRMIQ.

Family and domain databases

Gene3Di1.10.150.50. 2 hits.
InterProiIPR029515. Liprin.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
IPR021129. SAM_type1.
[Graphical view]
PANTHERiPTHR12587. PTHR12587. 1 hit.
PfamiPF00536. SAM_1. 2 hits.
PF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 3 hits.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 3 hits.
PROSITEiPS50105. SAM_DOMAIN. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RXQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMCEVMPTIS EAEGPPGGGG SHGSGSPSQP DADSHFEQLM VSMLEERDRL
60 70 80 90 100
LDTLRETQET LALTQGKLHE VGHERDSLQR QLNTALPQEF AALTKELNVC
110 120 130 140 150
REQLLEREEE IAELKAERNN TRLLLEHLEC LVSRHERSLR MTVVKRQAQS
160 170 180 190 200
PAGVSSEVEV LKALKSLFEH HKALDEKVRE RLRVALERCS LLEEELGATH
210 220 230 240 250
KELMILKEQN NQKKTLTDGL LDGNHEQESA PSTNGKRSSD GSLSHEDLAK
260 270 280 290 300
VLELQEVIDR QAREQSQMKE RLASLSSHAA ELEEDLDTAR KDLIKSEEMN
310 320 330 340 350
TKLQREVREA MAQKEDMEER ITTLEKRYLA AQREATSVHD LNDKLENEIA
360 370 380 390 400
NKDSMHRQTE DKNRQLQERL ELAEQKLQQT LRKAETLPEV EAELAQRVAA
410 420 430 440 450
LSKSGPLSSG SSAAKEAKLL ELTSKLRKAE ERHGNIEERL RQMEAQLEEK
460 470 480 490 500
NQELQRARQR EKMNEEHNKR LSDTVDKLLS ESNERLQLHL KERMAALEDK
510 520 530 540 550
NSLLREVENA KKQLEETQHD KDQLVVTIEA LKAELEQMRL RGPSLHHGRP
560 570 580 590 600
HLGSVPDFRF SVADGHVDAY STSAVLRRPQ KGRLAALRDE PSKVQTLNEQ
610 620 630 640 650
DWERAQQASV LANVAQAFES DVDVSDGEDD RDTLLSSVDL LSPSGQADAQ
660 670 680 690 700
TLAMMLQEQL DAINKEIRLI QEEKENTEQR AEEIESRVGS GSLDNLGRFR
710 720 730 740 750
SMSSIPPYPA SSLAGSSPPG SGRSTPRRVP HSPAREVDRL GVMTLPSDLR
760 770 780 790 800
KHRRQLPASR EEVRDDKTTI KCETSPPSSP RPLRLDRMHK GAPHTVSHED
810 820 830 840 850
IRDLRNSTGS QDGPVSNPSS SNSSQDSLHK APKKKGIKSS IGRLFGKKEK
860 870 880 890 900
GRPGPLGKES PGQVGVSETE NSSQDALGLS KLGGQAEKNR KLQKKHELLE
910 920 930 940 950
EARRQGLPFA QWDGPTVVVW LELWVGMPAW YVAACRANVK SGAIMSALSD
960 970 980 990 1000
TEIQREIGIS NPLHRLKLRL AIQEIMSLTS PSAPPTSRTT TGNVWLTHEE
1010 1020 1030 1040 1050
METLTATPQT EDEEGSWAQT LAYGDMNHEW IGNEWLPSLG LPQYRSYFME
1060 1070 1080 1090 1100
CLVDARMLDH LTKKDLRGQL KMVDSFHRNS FQCGIMCLRR LNYDRKELER
1110 1120 1130 1140 1150
KREESQNETR DVLVWSNDRV IRWILSIGLK EYANNLIESG VHGALLALDE
1160 1170 1180 1190 1200
TFDFSALALL LQIPTQNTQA RAVLEREFNN LLITGTDRRF DEDDDKSFRR
1210 1220 1230 1240 1250
APSWRKKFRP KDIRGLASGS AETLPANFRV TSSMSSPSMQ PKKVQMDGSV
1260
SGAQRLDSAT VRTYSC
Length:1,266
Mass (Da):142,676
Last modified:July 1, 2008 - v1
Checksum:i545C3EFBF1067EBC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140268 Genomic DNA. No translation available.
AC153792 Genomic DNA. No translation available.
BC157936 mRNA. Translation: AAI57937.1.
BC172096 mRNA. Translation: AAI72096.1.
RefSeqiNP_001182015.1. NM_001195086.1.
UniGeneiMm.490347.

Genome annotation databases

EnsembliENSMUST00000182226; ENSMUSP00000138312; ENSMUSG00000037519.
GeneIDi233977.
KEGGimmu:233977.
UCSCiuc012fxz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140268 Genomic DNA. No translation available.
AC153792 Genomic DNA. No translation available.
BC157936 mRNA. Translation: AAI57937.1.
BC172096 mRNA. Translation: AAI72096.1.
RefSeqiNP_001182015.1. NM_001195086.1.
UniGeneiMm.490347.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000182226; ENSMUSP00000138312; ENSMUSG00000037519.
GeneIDi233977.
KEGGimmu:233977.
UCSCiuc012fxz.1. mouse.

Organism-specific databases

CTDi8500.
MGIiMGI:1924750. Ppfia1.

Phylogenomic databases

eggNOGiNOG261376.
GeneTreeiENSGT00760000119138.
HOVERGENiHBG052330.
OMAiNEIRMIQ.

Enzyme and pathway databases

ReactomeiREACT_205038. Acetylcholine Neurotransmitter Release Cycle.
REACT_229514. Glutamate Neurotransmitter Release Cycle.
REACT_242222. Norepinephrine Neurotransmitter Release Cycle.

Miscellaneous databases

NextBioi381971.
SOURCEiSearch...

Gene expression databases

GenevestigatoriB2RXQ2.

Family and domain databases

Gene3Di1.10.150.50. 2 hits.
InterProiIPR029515. Liprin.
IPR001660. SAM.
IPR013761. SAM/pointed.
IPR011510. SAM_2.
IPR021129. SAM_type1.
[Graphical view]
PANTHERiPTHR12587. PTHR12587. 1 hit.
PfamiPF00536. SAM_1. 2 hits.
PF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 3 hits.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 3 hits.
PROSITEiPS50105. SAM_DOMAIN. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (JUL-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB2RXQ2_MOUSE
AccessioniPrimary (citable) accession number: B2RXQ2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: March 4, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.