B2RXA7 (B2RXA7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cytochrome P450, family 26, subfamily c, polypeptide 1 EMBL AAI51099.1

Submitted name:
Protein Cyp26c1 Ensembl ENSMUSP00000073105

Gene names

Name:

Cyp26c1 EMBL AAI51099.1 Ensembl ENSMUSP00000073105 MGI 2679699

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	518 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cytochrome P450 family. RuleBase RU000461

Ontologies

Keywords
Ligand	Heme RuleBase RU000461 Iron Metal-binding
Molecular function	Monooxygenase RuleBase RU000461 Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	anterior/posterior pattern specification Inferred from genetic interaction PubMed 17067568. Source: MGI central nervous system development Inferred from genetic interaction PubMed 17067568. Source: MGI neural crest cell development Inferred from genetic interaction PubMed 17067568. Source: MGI organelle fusion Inferred from genetic interaction PubMed 17067568. Source: MGI retinoic acid catabolic process Inferred from electronic annotation. Source: Compara
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro retinoic acid 4-hydroxylase activity Inferred from electronic annotation. Source: Compara retinoic acid binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2RXA7 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 0A78D11F556AF618	FASTA	518	57,026
	10 20 30 40 50 60 MISWGLSCLS VLGAAGTTLL CAGLLLGLAQ QLWTLRWTLS RDWASTLPLP KGSMGWPFFG 70 80 90 100 110 120 ETLHWLVQGS RFHSSRRERY GTVFKTHLLG RPVIRVSGAE NVRTILLGEH RLVRSQWPQS 130 140 150 160 170 180 AHILLGSHTL LGAVGEPHRQ RRKVLARVFS RSSLEQFVPR LQGALRREVR SWCAAQRPVA 190 200 210 220 230 240 VYQAAKALTF RMAARILLGL QLDEARCTEL AHTFEQLVEN LFSLPLDVPF SGLRKGIRAR 250 260 270 280 290 300 DQLYEHLDEA VAEKLQEKQT AEPGDALLLI INSARELGHE PSVQELKELA VELLFAAFFT 310 320 330 340 350 360 TASASTSLIL LLLQHPAAIT KIQQELSAQG LGRACTCTPR ASGSPPDCGC EPDLSLAMLG 370 380 390 400 410 420 RLRYVDCVVK EVLRLLPPVS GGYRTALRTF ELDGYQIPKG WSVMYSIRDT HETAAVYRSP 430 440 450 460 470 480 PEGFDPERFG VESGDARGSG GRFHYIPFGG GARSCLGQEL AQAVLQLLAV ELVRTARWEL 490 500 510 ATPAFPVMQT VPIVHPVDGL LLFFHPLPTS GAGDGLPF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAI51099.1 and Testicle EMBL AAI51107.1.
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000073105.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000073105.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC110212 Genomic DNA. No translation available. BC151098 mRNA. Translation: AAI51099.1. BC151106 mRNA. Translation: AAI51107.1.
IPI	IPI00468389.
RefSeq	NP_001098671.1. NM_001105201.1.
UniGene	Mm.457750.
3D structure databases
SMR	B2RXA7. Positions 46-507.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000073105.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000073391; ENSMUSP00000073105; ENSMUSG00000062432.
GeneID	546726.
KEGG	mmu:546726.
UCSC	uc012ble.1. mouse.
Organism-specific databases
CTD	340665.
MGI	MGI:2679699. Cyp26c1.
Phylogenomic databases
eggNOG	COG2124.
GeneTree	ENSGT00660000095370.
HOGENOM	HOG000220829.
HOVERGEN	HBG051099.
InParanoid	B2RXA7.
KO	K12665.
OMA	DAQIADN.
OrthoDB	EOG48KRBB.
Gene expression databases
Genevestigator	B2RXA7.
Family and domain databases
Gene3D	1.10.630.10. 1 hit.
InterPro	IPR001128. Cyt_P450. IPR017972. Cyt_P450_CS. IPR002401. Cyt_P450_E_grp-I. [Graphical view]
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00463. EP450I. PR00385. P450.
SUPFAM	SSF48264. Cytochrome_P450. 1 hit.
PROSITE	PS00086. CYTOCHROME_P450. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	413785.
SOURCE	Search...

Entry information

Entry name

B2RXA7_MOUSE

Accession

Primary (citable) accession number: B2RXA7

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)