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B2RXA7

- B2RXA7_MOUSE

UniProt

B2RXA7 - B2RXA7_MOUSE

Protein
Submitted name:

Cytochrome P450, family 26, subfamily c, polypeptide 1

Gene

Cyp26c1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (01 Jul 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. iron ion binding Source: InterPro
    3. retinoic acid 4-hydroxylase activity Source: Ensembl
    4. retinoic acid binding Source: Ensembl

    GO - Biological processi

    1. anterior/posterior pattern specification Source: MGI
    2. central nervous system development Source: MGI
    3. neural crest cell development Source: MGI
    4. organelle fusion Source: MGI
    5. retinoic acid catabolic process Source: Ensembl

    Keywords - Molecular functioni

    MonooxygenaseUniRule annotation, Oxidoreductase

    Keywords - Ligandi

    HemeUniRule annotation, Iron, Metal-binding

    Enzyme and pathway databases

    ReactomeiREACT_213027. Vitamins.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cytochrome P450, family 26, subfamily c, polypeptide 1Imported
    Submitted name:
    Protein Cyp26c1Imported
    Gene namesi
    Name:Cyp26c1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 19

    Organism-specific databases

    MGIiMGI:2679699. Cyp26c1.

    Expressioni

    Gene expression databases

    GenevestigatoriB2RXA7.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000073105.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome P450 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2124.
    GeneTreeiENSGT00660000095370.
    HOGENOMiHOG000220829.
    HOVERGENiHBG051099.
    InParanoidiB2RXA7.
    KOiK12665.
    OMAiHAICATI.
    OrthoDBiEOG7F24SP.
    TreeFamiTF105093.

    Family and domain databases

    Gene3Di1.10.630.10. 1 hit.
    InterProiIPR001128. Cyt_P450.
    IPR017972. Cyt_P450_CS.
    IPR002401. Cyt_P450_E_grp-I.
    [Graphical view]
    PfamiPF00067. p450. 1 hit.
    [Graphical view]
    PRINTSiPR00463. EP450I.
    PR00385. P450.
    SUPFAMiSSF48264. SSF48264. 1 hit.
    PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2RXA7-1 [UniParc]FASTAAdd to Basket

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    MISWGLSCLS VLGAAGTTLL CAGLLLGLAQ QLWTLRWTLS RDWASTLPLP    50
    KGSMGWPFFG ETLHWLVQGS RFHSSRRERY GTVFKTHLLG RPVIRVSGAE 100
    NVRTILLGEH RLVRSQWPQS AHILLGSHTL LGAVGEPHRQ RRKVLARVFS 150
    RSSLEQFVPR LQGALRREVR SWCAAQRPVA VYQAAKALTF RMAARILLGL 200
    QLDEARCTEL AHTFEQLVEN LFSLPLDVPF SGLRKGIRAR DQLYEHLDEA 250
    VAEKLQEKQT AEPGDALLLI INSARELGHE PSVQELKELA VELLFAAFFT 300
    TASASTSLIL LLLQHPAAIT KIQQELSAQG LGRACTCTPR ASGSPPDCGC 350
    EPDLSLAMLG RLRYVDCVVK EVLRLLPPVS GGYRTALRTF ELDGYQIPKG 400
    WSVMYSIRDT HETAAVYRSP PEGFDPERFG VESGDARGSG GRFHYIPFGG 450
    GARSCLGQEL AQAVLQLLAV ELVRTARWEL ATPAFPVMQT VPIVHPVDGL 500
    LLFFHPLPTS GAGDGLPF 518
    Length:518
    Mass (Da):57,026
    Last modified:July 1, 2008 - v1
    Checksum:i0A78D11F556AF618
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC110212 Genomic DNA. No translation available.
    BC151098 mRNA. Translation: AAI51099.1.
    BC151106 mRNA. Translation: AAI51107.1.
    RefSeqiNP_001098671.1. NM_001105201.1.
    UniGeneiMm.457750.

    Genome annotation databases

    EnsembliENSMUST00000073391; ENSMUSP00000073105; ENSMUSG00000062432.
    GeneIDi546726.
    KEGGimmu:546726.
    UCSCiuc012ble.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC110212 Genomic DNA. No translation available.
    BC151098 mRNA. Translation: AAI51099.1 .
    BC151106 mRNA. Translation: AAI51107.1 .
    RefSeqi NP_001098671.1. NM_001105201.1.
    UniGenei Mm.457750.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000073105.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000073391 ; ENSMUSP00000073105 ; ENSMUSG00000062432 .
    GeneIDi 546726.
    KEGGi mmu:546726.
    UCSCi uc012ble.1. mouse.

    Organism-specific databases

    CTDi 340665.
    MGIi MGI:2679699. Cyp26c1.

    Phylogenomic databases

    eggNOGi COG2124.
    GeneTreei ENSGT00660000095370.
    HOGENOMi HOG000220829.
    HOVERGENi HBG051099.
    InParanoidi B2RXA7.
    KOi K12665.
    OMAi HAICATI.
    OrthoDBi EOG7F24SP.
    TreeFami TF105093.

    Enzyme and pathway databases

    Reactomei REACT_213027. Vitamins.

    Miscellaneous databases

    NextBioi 413785.
    PROi B2RXA7.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori B2RXA7.

    Family and domain databases

    Gene3Di 1.10.630.10. 1 hit.
    InterProi IPR001128. Cyt_P450.
    IPR017972. Cyt_P450_CS.
    IPR002401. Cyt_P450_E_grp-I.
    [Graphical view ]
    Pfami PF00067. p450. 1 hit.
    [Graphical view ]
    PRINTSi PR00463. EP450I.
    PR00385. P450.
    SUPFAMi SSF48264. SSF48264. 1 hit.
    PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported and TesticleImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB2RXA7_MOUSE
    AccessioniPrimary (citable) accession number: B2RXA7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 2008
    Last sequence update: July 1, 2008
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3