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B2RXA7

- B2RXA7_MOUSE

UniProt

B2RXA7 - B2RXA7_MOUSE

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Protein
Submitted name:

Cytochrome P450, family 26, subfamily c, polypeptide 1

Gene
Cyp26c1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. retinoic acid 4-hydroxylase activity Source: Ensembl
  4. retinoic acid binding Source: Ensembl

GO - Biological processi

  1. anterior/posterior pattern specification Source: MGI
  2. central nervous system development Source: MGI
  3. neural crest cell development Source: MGI
  4. organelle fusion Source: MGI
  5. retinoic acid catabolic process Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiREACT_213027. Vitamins.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 26, subfamily c, polypeptide 1Imported
Submitted name:
Protein Cyp26c1Imported
Gene namesi
Name:Cyp26c1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 19

Organism-specific databases

MGIiMGI:2679699. Cyp26c1.

Expressioni

Gene expression databases

GenevestigatoriB2RXA7.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073105.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2124.
GeneTreeiENSGT00660000095370.
HOGENOMiHOG000220829.
HOVERGENiHBG051099.
InParanoidiB2RXA7.
KOiK12665.
OMAiHAICATI.
OrthoDBiEOG7F24SP.
TreeFamiTF105093.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RXA7-1 [UniParc]FASTAAdd to Basket

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MISWGLSCLS VLGAAGTTLL CAGLLLGLAQ QLWTLRWTLS RDWASTLPLP    50
KGSMGWPFFG ETLHWLVQGS RFHSSRRERY GTVFKTHLLG RPVIRVSGAE 100
NVRTILLGEH RLVRSQWPQS AHILLGSHTL LGAVGEPHRQ RRKVLARVFS 150
RSSLEQFVPR LQGALRREVR SWCAAQRPVA VYQAAKALTF RMAARILLGL 200
QLDEARCTEL AHTFEQLVEN LFSLPLDVPF SGLRKGIRAR DQLYEHLDEA 250
VAEKLQEKQT AEPGDALLLI INSARELGHE PSVQELKELA VELLFAAFFT 300
TASASTSLIL LLLQHPAAIT KIQQELSAQG LGRACTCTPR ASGSPPDCGC 350
EPDLSLAMLG RLRYVDCVVK EVLRLLPPVS GGYRTALRTF ELDGYQIPKG 400
WSVMYSIRDT HETAAVYRSP PEGFDPERFG VESGDARGSG GRFHYIPFGG 450
GARSCLGQEL AQAVLQLLAV ELVRTARWEL ATPAFPVMQT VPIVHPVDGL 500
LLFFHPLPTS GAGDGLPF 518
Length:518
Mass (Da):57,026
Last modified:July 1, 2008 - v1
Checksum:i0A78D11F556AF618
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC110212 Genomic DNA. No translation available.
BC151098 mRNA. Translation: AAI51099.1.
BC151106 mRNA. Translation: AAI51107.1.
RefSeqiNP_001098671.1. NM_001105201.1.
UniGeneiMm.457750.

Genome annotation databases

EnsembliENSMUST00000073391; ENSMUSP00000073105; ENSMUSG00000062432.
GeneIDi546726.
KEGGimmu:546726.
UCSCiuc012ble.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC110212 Genomic DNA. No translation available.
BC151098 mRNA. Translation: AAI51099.1 .
BC151106 mRNA. Translation: AAI51107.1 .
RefSeqi NP_001098671.1. NM_001105201.1.
UniGenei Mm.457750.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000073105.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000073391 ; ENSMUSP00000073105 ; ENSMUSG00000062432 .
GeneIDi 546726.
KEGGi mmu:546726.
UCSCi uc012ble.1. mouse.

Organism-specific databases

CTDi 340665.
MGIi MGI:2679699. Cyp26c1.

Phylogenomic databases

eggNOGi COG2124.
GeneTreei ENSGT00660000095370.
HOGENOMi HOG000220829.
HOVERGENi HBG051099.
InParanoidi B2RXA7.
KOi K12665.
OMAi HAICATI.
OrthoDBi EOG7F24SP.
TreeFami TF105093.

Enzyme and pathway databases

Reactomei REACT_213027. Vitamins.

Miscellaneous databases

NextBioi 413785.
PROi B2RXA7.
SOURCEi Search...

Gene expression databases

Genevestigatori B2RXA7.

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view ]
Pfami PF00067. p450. 1 hit.
[Graphical view ]
PRINTSi PR00463. EP450I.
PR00385. P450.
SUPFAMi SSF48264. SSF48264. 1 hit.
PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported and TesticleImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB2RXA7_MOUSE
AccessioniPrimary (citable) accession number: B2RXA7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: September 3, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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