ID   B2RX70_MOUSE            Unreviewed;      1026 AA.
AC   B2RX70;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Cadherin-like and PC-esterase domain containing 1 {ECO:0000313|Ensembl:ENSMUSP00000111041.3};
GN   Name=Cped1 {ECO:0000313|Ensembl:ENSMUSP00000111041.3,
GN   ECO:0000313|MGI:MGI:2444814};
GN   Synonyms=A430107O13Rik {ECO:0000313|EMBL:AAI51019.1,
GN   ECO:0000313|MGI:MGI:2444814};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAI51019.1};
RN   [1] {ECO:0000313|EMBL:AAI51019.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain {ECO:0000313|EMBL:AAI51019.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA   Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA   Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA   Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA   Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA   Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA   Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA   Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA   Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA   Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA   Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA   Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA   Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA   Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA   Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA   Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA   Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000111041.3, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000111041.3,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000111041.3}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000111041.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; BC151018; AAI51019.1; -; mRNA.
DR   RefSeq; NP_001074820.1; NM_001081351.1.
DR   RefSeq; XP_006505101.1; XM_006505038.3.
DR   STRING; 10090.ENSMUSP00000111041; -.
DR   PaxDb; 10090-ENSMUSP00000111041; -.
DR   ProteomicsDB; 330348; -.
DR   Antibodypedia; 2305; 55 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000115383.9; ENSMUSP00000111041.3; ENSMUSG00000062980.16.
DR   GeneID; 214642; -.
DR   KEGG; mmu:214642; -.
DR   UCSC; uc009bav.1; mouse.
DR   AGR; MGI:2444814; -.
DR   CTD; 79974; -.
DR   MGI; MGI:2444814; Cped1.
DR   VEuPathDB; HostDB:ENSMUSG00000062980; -.
DR   eggNOG; ENOG502QQAY; Eukaryota.
DR   GeneTree; ENSGT00390000015216; -.
DR   OMA; HRYTVVI; -.
DR   OrthoDB; 1097907at2759; -.
DR   TreeFam; TF332741; -.
DR   BioGRID-ORCS; 214642; 2 hits in 78 CRISPR screens.
DR   ChiTaRS; Cped1; mouse.
DR   Proteomes; UP000000589; Chromosome 6.
DR   Bgee; ENSMUSG00000062980; Expressed in meninx of telencephalon and 124 other cell types or tissues.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISO:MGI.
DR   InterPro; IPR025883; Cadherin-like_b_sandwich.
DR   PANTHER; PTHR14776; CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR14776:SF1; CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF12733; Cadherin-like; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|ProteomicsDB:B2RX70};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          580..663
FT                   /note="Cadherin-like beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF12733"
SQ   SEQUENCE   1026 AA;  116834 MW;  7874393FD63D6641 CRC64;
     MVCRPGFLCR RRFCPRPFLV GLVVAICLFY QTLTLRGTKK IAADVSGTVP HTPSQTQASR
     CEEGYRQDKQ CFLLSASTQE TRKIEESIER HFGSLSRRAV LHRPPSSSRA QLQIHQHLLA
     QHGYSVVTVE ERLGGGLGPE LLDQGGLNSW DLFICLPSRE ADGKPCIPRE HMCRLSLHQR
     VNVLPEIQPQ LCRREGLCEI TRRFPEFRLP VSSSVCLDQE TQSRLRVSSH LSKAEKPHVW
     KPRDWHRKQL NLTTVVAPHE AISRAEELSV ILKAYVLVTS LRPLRAFIHS TGTVWSPPKK
     KRFTVKLQMF FETFLRTSSP LQALDSMKEA ISKLLLVAEV FSDASTLGPK TFNRCIQCFQ
     LLTFDVGYGD SGYPVVLQVH EHLHFHDDEN FSAEDQNAEN IILRDTFDFL FSNASSLSMV
     SEMLQRRDSA GAFVDGNYEK ELNQCLSFEE IHSIRTFVKE LGSLGQFQLL FPSSVPGIRS
     LMGEFYDMAT PGSVLSQYWS LLNVFEQFWL MNKKAQLQPL EWNSPTRNET IEEPPRSLEG
     IQSGKDAAPR VLFENKDIHC SDEEDVLCHI KKIITHPRLE LSPEFNPKIK EYYCEVPFDV
     LTVRIGAETS KCQCKAHLQE QAGPSFATYP LGIGMNRISV LVVDESHAGG AALTTYKLTI
     YREDRPSLPF FEDFTACGFV QDCDLLIHPE ETCGLQPISA EYIKAISQPE IESCPSGDTK
     GQWIVPCLTC SDNRTCDWRE ITWQPHNCQH NILTKPELQQ CLQGRKILFI GDSTNRGMMY
     YLIERLNETL QEWQKLHGTK LYPSVNGGKS PISYSYYPQF WIRPSLRPAF EKALEHLLQR
     SQPLENTDQT VLVVGGVQWL NSNHLQIIHK VLKRENLLNI LVIIKTLGIG FHLPVDGVHF
     LTQGEVRNLY KENLSILETA KKYGYEVVDT FTITMGRHKE FLQGNCGCHF HEVVKSKLSR
     QHHVIKMKRS KNHIVGKYFS SQSKLKQHNS VPNLHSPYHV RGPINQVCAE ILLSRMCASQ
     RSAQAP
//