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Protein
Submitted name:

MCG2960, isoform CRA_b

Gene

Steap2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
MCG2960, isoform CRA_bImported
Submitted name:
Six transmembrane epithelial antigen of prostate 2Imported
Submitted name:
Steap2 proteinImported
Gene namesi
Name:Steap2Imported
ORF Names:mCG_2960Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1921301 Steap2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei210 – 231HelicalSequence analysisAdd BLAST22
Transmembranei260 – 283HelicalSequence analysisAdd BLAST24
Transmembranei304 – 325HelicalSequence analysisAdd BLAST22
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Transmembranei390 – 411HelicalSequence analysisAdd BLAST22
Transmembranei431 – 453HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000015653

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 117F420_oxidoredInterPro annotationAdd BLAST87
Domaini259 – 404Ferric oxidoreductaseInterPro annotationAdd BLAST146

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IF4F Eukaryota
COG2085 LUCA
HOVERGENiHBG054379
KOiK14738
OMAiTHHEDAV
OrthoDBiEOG091G0F9X

Family and domain databases

InterProiView protein in InterPro
IPR013130 Fe3_Rdtase_TM_dom
IPR036291 NAD(P)-bd_dom_sf
IPR028939 P5C_Rdtase_cat_N
PfamiView protein in Pfam
PF03807 F420_oxidored, 1 hit
PF01794 Ferric_reduct, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

B2RX33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESISMMGSP KSLETFLPNG INGIKDARQV TVGVIGSGDF AKSLTIRLIR
60 70 80 90 100
CGYHVVIGSR NPKFASEFFP HVVDVTHHED ALTKTNIIFV AIHREHYTSL
110 120 130 140 150
WDLRHLLVGK ILIDVSNNMR VNQYPESNAE YLASLFPDSL IVKGFNVISA
160 170 180 190 200
WALQLGPKDA SRQVYICSNN IQARQQVIEL ARQLNFIPVD LGSLSSAKEI
210 220 230 240 250
ENLPLRLFTL WRGPVVVAIS LATFFFLYSF VRDVIHPYAR NQQSDFYKIP
260 270 280 290 300
IEIVNKTLPI VAITLLSLVY LAGLLAAAYQ LYYGTKYRRF PPWLDTWLQC
310 320 330 340 350
RKQLGLLSFF FAVVHVAYSL CLPMRRSERY LFLNMAYQQV HANIENAWNE
360 370 380 390 400
EEVWRIEMYI SFGIMSLGLL SLLAVTSIPS VSNALNWREF SFIQSTLGYV
410 420 430 440 450
ALLITTFHVL IYGWKRAFAE EYYRFYTPPN FVLALVLPSI VILGKMILLL
460 470 480
PCISRKLKRI KKGWEKSQFL DEGMGGAVPH LSPERVTVM
Length:489
Mass (Da):55,760
Last modified:July 1, 2008 - v1
Checksum:i98CD63D59DDDF24C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC150881 mRNA Translation: AAI50882.1
BC150889 mRNA Translation: AAI50890.1
BC150997 mRNA Translation: AAI50998.1
BC151008 mRNA Translation: AAI51009.1
CH466600 Genomic DNA Translation: EDL14647.1
CH466600 Genomic DNA Translation: EDL14649.1
RefSeqiNP_001096626.1, NM_001103156.2
NP_001096627.1, NM_001103157.2
NP_001272398.1, NM_001285469.1
NP_001272399.1, NM_001285470.1
NP_083010.2, NM_028734.5
XP_011238977.1, XM_011240675.2
UniGeneiMm.274956

Genome annotation databases

GeneIDi74051
KEGGimmu:74051

Similar proteinsi

Entry informationi

Entry nameiB2RX33_MOUSE
AccessioniPrimary (citable) accession number: B2RX33
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: March 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health