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B2RV73

- B2RV73_MOUSE

UniProt

B2RV73 - B2RV73_MOUSE

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Protein
Submitted name:

Protein O-fucosyltransferase 2

Gene

Pofut2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. fucosyltransferase activity Source: MGI
  2. peptide-O-fucosyltransferase activity Source: Ensembl

GO - Biological processi

  1. fucosylation Source: MGI
  2. mesoderm formation Source: MGI
  3. regulation of epithelial to mesenchymal transition Source: MGI
  4. regulation of gene expression Source: MGI
  5. regulation of secretion Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, Transferase

Protein family/group databases

CAZyiGT68. Glycosyltransferase Family 68.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein O-fucosyltransferase 2Imported
Submitted name:
Protein O-fucosyltransferase 2, isoform CRA_bImported
Gene namesi
Name:Pofut2Imported
ORF Names:mCG_3385Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1916863. Pofut2.

Subcellular locationi

GO - Cellular componenti

  1. Golgi apparatus Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriB2RV73.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG053367.
KOiK03691.
OMAiICAHARF.

Family and domain databases

InterProiIPR019378. GDP-Fuc_O-FucTrfase.
[Graphical view]
PfamiPF10250. O-FucT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RV73 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAALSVVCLL LAAASWRPVS ASGEEFWPGQ SAADILSGAA SRRRYLLYDV
60 70 80 90 100
NPPEGFNLRR DVYIRVASLL KTLLKTEEWV LVLPPWGRLY HWQSPDIHQV
110 120 130 140 150
RIPWSEFFDL PSLNKNIPVI EYEQFIAESG GPFIDQVYVL QGYAEGWKEG
160 170 180 190 200
TWEEKVDARP CIDPLLYSQD KHEYYRGWFW GYEETRGLNV SCLSVQGSAS
210 220 230 240 250
IVAPVLLKNT SARSVMLDRA ENLLHDHYGG REYWDTRRSM VFAKHLRAVG
260 270 280 290 300
DEFRSQHLNS TDAADKMAPE EDWTKMKVKL GSALGGPYLG VHLRRKDFIW
310 320 330 340 350
GHREDVPSLE GAVKKIRSLM KTHQLDKVFV ATDAIRKEQE ELRKLLPEMV
360 370 380 390 400
RFEPTWEELE LYKDGGVAII DQWICAHARF FIGTSVSTFS FRIHEEREIL
410 420
GLDPKTTYNR FCGDQEKACE QPTHWKIAY
Length:429
Mass (Da):49,429
Last modified:July 1, 2008 - v1
Checksum:i0E7AFF5F1CD33560
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC147077 mRNA. Translation: AAI47078.1.
BC147078 mRNA. Translation: AAI47079.1.
CH466553 Genomic DNA. Translation: EDL31818.1.
RefSeqiNP_084538.2. NM_030262.3.
UniGeneiMm.203556.

Genome annotation databases

GeneIDi80294.
KEGGimmu:80294.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC147077 mRNA. Translation: AAI47078.1 .
BC147078 mRNA. Translation: AAI47079.1 .
CH466553 Genomic DNA. Translation: EDL31818.1 .
RefSeqi NP_084538.2. NM_030262.3.
UniGenei Mm.203556.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GT68. Glycosyltransferase Family 68.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 80294.
KEGGi mmu:80294.

Organism-specific databases

CTDi 23275.
MGIi MGI:1916863. Pofut2.

Phylogenomic databases

HOVERGENi HBG053367.
KOi K03691.
OMAi ICAHARF.

Miscellaneous databases

ChiTaRSi POFUT2. mouse.
NextBioi 350013.
SOURCEi Search...

Gene expression databases

Genevestigatori B2RV73.

Family and domain databases

InterProi IPR019378. GDP-Fuc_O-FucTrfase.
[Graphical view ]
Pfami PF10250. O-FucT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiB2RV73_MOUSE
AccessioniPrimary (citable) accession number: B2RV73
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: October 29, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)