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B2RUS7 (B2RUS7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Protein Abcc8 Ensembl ENSMUSP00000033123
Gene names
Name:Abcc8 EMBL AAI41412.1 MGI 1352629 Ensembl ENSMUSP00000033123
OrganismMus musculus (Mouse) [Reference proteome] EMBL AAI41412.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length1588 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains ABC transmembrane type-1 domains. SAAS SAAS011527

Sequences

Sequence LengthMass (Da)Tools
B2RUS7 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 661159D6319EFD53

FASTA1,588178,071
        10         20         30         40         50         60 
MPLAFCGTEN HSAAYRVDQG VLNNGCFVDA LNVVPHVFLL FITFPILFIG WGSQSSKVHI 

        70         80         90        100        110        120 
HHSTWLHFPG HNLRWILTFM LLFVLVCEIA EGILSDGVTE SRHLHLYMPA GMAFMAAITS 

       130        140        150        160        170        180 
VVYYHNIETS NFPKLLIALL IYWTLAFITK TIKFVKFYDH AIGFSQLRFC LTGLLVILYG 

       190        200        210        220        230        240 
MLLLVEINVI RVRRYIFFKT PREVKPPEDL QDLGVRFLQP FVNLLSKGTY WWMNAFIKTA 

       250        260        270        280        290        300 
HRKPIDLRAI GKLPIAMRAL TNYQRLCAAF DAQARKDTQS QQGARAIWRA LCHAFGRRLV 

       310        320        330        340        350        360 
LSSTFRILAD LLGFAGPLCI FGIVDHLGKE NHVFQPKTQF LGVYFVSSQE FLGNAYVLAV 

       370        380        390        400        410        420 
LLFLALLLQR TFLQASYYVA IETGINLRGA IQTKIYNKIM HLSTSNLSMG EMTAGQICNL 

       430        440        450        460        470        480 
VAIDTNQLMW FFFLCPNLWA MPVQIIVGVI LLYYILGVSA LIGAAVIILL APVQYFVATK 

       490        500        510        520        530        540 
LSQAQRSTLE YSNERLKQTN EMLRGIKLLK LYAWENIFCS RVEMTRRKEM TSLRAFAVYT 

       550        560        570        580        590        600 
SISIFMNTAI PIAAVLITFV GHVSFFKESD FSPSVAFASL SLFHILVTPL FLLSSVVRST 

       610        620        630        640        650        660 
VKALVSVQKL SEFLSSAEIR EEQCAPREPA PQGQAGKYQA VPLKVVNRKR PAREEVRDLL 

       670        680        690        700        710        720 
GPLQRLTPSM DGDADNFCVQ IIGGFFTWTP DGIPTLSNIT IRIPRGQLTM IVGQVGCGKS 

       730        740        750        760        770        780 
SLLLATLGEM QRVSGAVFWN SSLPDSEGED PRYCLRTSNP ERETAADSDA RSRGPVAYAS 

       790        800        810        820        830        840 
QKPWLLNATV EENITFESPF NKQRYKMVIE ACSLQPDIDI LPHGDQTQIG ERGINLSGGQ 

       850        860        870        880        890        900 
RQRISVARAL YQHTNVVFLD DPFSALDVHL SDHLMQAGIL ELLRDDKRTV VLVTHKLQYL 

       910        920        930        940        950        960 
PHADWIIAMK DGTIQREGTL KDFQRSECQL FEHWKTLMNR QDQELEKETV MERKAPEPSQ 

       970        980        990       1000       1010       1020 
GLPRAMSSRD GLLLDEDEEE EEAAESEEDD NLSSVLHQRA KIPWRACTKY LSSAGVLLLS 

      1030       1040       1050       1060       1070       1080 
LLVFSQLLKH MVLVAIDYWL AKWTDSALVL SPAARNCSLS QECALDQSVY AMVFTVLCSL 

      1090       1100       1110       1120       1130       1140 
GIALCLVTSV TVEWTGLKVA KRLHRSLLNR IILAPMRFFE TTPLGSILNR FSSDCNTIDQ 

      1150       1160       1170       1180       1190       1200 
HIPSTLECLS RSTLLCVSAL TVISYVTPVF LVALLPLAVV CYFIQKYFRV ASRDLQQLDD 

      1210       1220       1230       1240       1250       1260 
TTQLPLLSHF AETVEGLTTI RAFRYEARFQ QKLLEYTDSN NIASLFLTAA NRWLEVRMEY 

      1270       1280       1290       1300       1310       1320 
IGACVVLIAA ATSISNSLHR ELSAGLVGLG LTYALMVSNY LNWMVRNLAD MEIQLGAVKR 

      1330       1340       1350       1360       1370       1380 
IHTLLKTEAE SYEGLLAPSL IPKNWPDQGK IQIQNLSVRY DSSLKPVLKH VNALIAPGQK 

      1390       1400       1410       1420       1430       1440 
IGICGRTGSG KSSFSLAFFR MVDMFEGRII IDGIDIAKLP LHTLRSRLSI ILQDPVLFSG 

      1450       1460       1470       1480       1490       1500 
TIRFNLDPEK KCSDSTLWEA LEIAQLKLVV KALPGGLDAI ITEGGENFSQ GQRQLFCLAR 

      1510       1520       1530       1540       1550       1560 
AFVRKTSIFI MDEATASIDM ATENILQKVV MTAFADRTVV TIAHRVHTIL SADLVMVLKR 

      1570       1580 
GAILEFDKPE KLLSQKDSVF ASFVRADK 

« Hide

References

« Hide 'large scale' references
[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain EMBL AAI41412.1.
[2]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000033123.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000033123.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC115036 Genomic DNA. No translation available.
AC120135 Genomic DNA. No translation available.
BC141411 mRNA. Translation: AAI41412.1.
RefSeqNP_035640.2. NM_011510.3.
UniGeneMm.259076.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-58644N.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000033123; ENSMUSP00000033123; ENSMUSG00000040136.
GeneID20927.
KEGGmmu:20927.
UCSCuc009gye.1. mouse.

Organism-specific databases

CTD6833.
MGIMGI:1352629. Abcc8.

Phylogenomic databases

eggNOGCOG1132.
GeneTreeENSGT00750000117379.
HOVERGENHBG101342.
InParanoidB2RUS7.
KOK05032.
OMALAFCGSE.
OrthoDBEOG7MWGW0.
TreeFamTF105201.

Gene expression databases

GenevestigatorB2RUS7.

Family and domain databases

Gene3D3.40.50.300. 3 hits.
InterProIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR001140. ABC_transptr_TM_dom.
IPR027417. P-loop_NTPase.
IPR000388. Sulphorea_rcpt.
IPR000844. Surea_rcpt-1.
[Graphical view]
PfamPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
PRINTSPR01093. SULFNYLUR1.
PR01092. SULFNYLUREAR.
SMARTSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio299841.
PROB2RUS7.
SOURCESearch...

Entry information

Entry nameB2RUS7_MOUSE
AccessionPrimary (citable) accession number: B2RUS7
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)