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Protein

Zinc finger protein 551

Gene

Znf551

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri337 – 35923C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri365 – 38723C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri393 – 41523C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri421 – 44323C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri449 – 47123C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri477 – 49923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri505 – 52723C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri533 – 55523C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri561 – 58323C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri589 – 61123C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri617 – 63923C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri645 – 66723C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri673 – 69523C2H2-type 13PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 551
Gene namesi
Name:Znf551
Synonyms:Zfp551
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:3588205. Zfp551.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 696696Zinc finger protein 551PRO_0000358931Add
BLAST

Proteomic databases

PaxDbiB2RUI1.
PRIDEiB2RUI1.

PTM databases

iPTMnetiB2RUI1.
PhosphoSiteiB2RUI1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000034071.
ExpressionAtlasiB2RUI1. baseline and differential.
GenevisibleiB2RUI1. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000079222.

Structurei

3D structure databases

ProteinModelPortaliB2RUI1.
SMRiB2RUI1. Positions 257-696.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 11972KRABPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 13 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 KRAB domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri337 – 35923C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri365 – 38723C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri393 – 41523C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri421 – 44323C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri449 – 47123C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri477 – 49923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri505 – 52723C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri533 – 55523C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri561 – 58323C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri589 – 61123C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri617 – 63923C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri645 – 66723C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri673 – 69523C2H2-type 13PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000119107.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiB2RUI1.
KOiK09228.
OrthoDBiEOG091G02KC.
PhylomeDBiB2RUI1.
TreeFamiTF341078.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 13 hits.
InterProiIPR001909. KRAB.
IPR030754. ZNF551.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24387:SF212. PTHR24387:SF212. 2 hits.
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 8 hits.
PF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RUI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRARPREET SATWSLLPLQ NPMAVAMHRN IAQVPLTSEP VMELGLDVSF
60 70 80 90 100
EDVAIHFSQE EWVLLDKAQR LLYCSVMLEN LALVASLGSC TGMGDEDVTC
110 120 130 140 150
EPAEEVVCNT SPSPQETHLL EIPVPALEEA WHQNEFLSTQ PVQTLDLSRT
160 170 180 190 200
GSGLKEDSNR HWKSYSGEKS CERDSHRATA MSSCRSHGLT EPFIRGKDGE
210 220 230 240 250
EALSSIAGVQ QQGACHSEQP STGCLQQQAT CIREQPYSSA KCGQALLNGE
260 270 280 290 300
KHCKDGECQK GSSCKHTLVQ CPSASSEKRP SECSKYEKAF SCSYKHAQHQ
310 320 330 340 350
DSHSGKRTHE HSQHEKPFSK KCRLNTQDRI CPQERPYKCT ECGKAFIYKS
360 370 380 390 400
ELVYHQRHHS ARVHYECVEC RKSFTYKSNL TEHQRIHTGE RPYQCEQCGK
410 420 430 440 450
SFRQNSSLFR HHRIHTGERP YECSECGKSF RQIFNLIRHR RVHTGEMPHQ
460 470 480 490 500
CADCGKAFSC KAELSQHERI HSGEKPYECS ECGKYFRQFS NLIRHRRVHT
510 520 530 540 550
GDRPYKCSEC EKSFSRKFIL VQHQRVHTGE RPYKCGECGT SFTRKSDLIQ
560 570 580 590 600
HQRIHTGTRP YECEECGKSF RQCSSLIQHR RVHTGEKPYE CIECGKAFSQ
610 620 630 640 650
SASLIQHQRL HTGERPYECS ECGKSFSQSA SLIQHQRSHS GEKPFECSDC
660 670 680 690
SKPFTHKSDL IQHRRVHTGE RPYECHDCEK SFSRRSNLVR HQRVHT
Length:696
Mass (Da):79,722
Last modified:January 20, 2009 - v2
Checksum:i8F2FE3440507C9DC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti421 – 4211Y → N in BAE23302 (PubMed:16141072).Curated
Sequence conflicti424 – 4241S → Y in AAI41161 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK137311 mRNA. Translation: BAE23302.1.
AC114404 Genomic DNA. No translation available.
BC141160 mRNA. Translation: AAI41161.1.
CCDSiCCDS20809.1.
RefSeqiNP_001028992.2. NM_001033820.3.
UniGeneiMm.361832.

Genome annotation databases

EnsembliENSMUST00000080348; ENSMUSP00000079222; ENSMUSG00000034071.
GeneIDi619331.
KEGGimmu:619331.
UCSCiuc009fea.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK137311 mRNA. Translation: BAE23302.1.
AC114404 Genomic DNA. No translation available.
BC141160 mRNA. Translation: AAI41161.1.
CCDSiCCDS20809.1.
RefSeqiNP_001028992.2. NM_001033820.3.
UniGeneiMm.361832.

3D structure databases

ProteinModelPortaliB2RUI1.
SMRiB2RUI1. Positions 257-696.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000079222.

PTM databases

iPTMnetiB2RUI1.
PhosphoSiteiB2RUI1.

Proteomic databases

PaxDbiB2RUI1.
PRIDEiB2RUI1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000080348; ENSMUSP00000079222; ENSMUSG00000034071.
GeneIDi619331.
KEGGimmu:619331.
UCSCiuc009fea.3. mouse.

Organism-specific databases

CTDi619331.
MGIiMGI:3588205. Zfp551.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000119107.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiB2RUI1.
KOiK09228.
OrthoDBiEOG091G02KC.
PhylomeDBiB2RUI1.
TreeFamiTF341078.

Miscellaneous databases

PROiB2RUI1.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034071.
ExpressionAtlasiB2RUI1. baseline and differential.
GenevisibleiB2RUI1. MM.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 13 hits.
InterProiIPR001909. KRAB.
IPR030754. ZNF551.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24387:SF212. PTHR24387:SF212. 2 hits.
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 8 hits.
PF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZN551_MOUSE
AccessioniPrimary (citable) accession number: B2RUI1
Secondary accession number(s): Q3UVG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 20, 2009
Last modified: September 7, 2016
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.