Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Map4k4 protein

Gene

Map4k4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Map4k4 proteinImported
Submitted name:
Mitogen-activated protein kinase kinase kinase kinase 4Imported
Gene namesi
Name:Map4k4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1349394. Map4k4.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129796.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 289265Protein kinaseInterPro annotationAdd
BLAST
Domaini908 – 1195288CNHInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili384 – 492109Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0587. Eukaryota.
ENOG410YBF5. LUCA.
GeneTreeiENSGT00810000125351.
HOVERGENiHBG036506.

Family and domain databases

InterProiIPR001180. CNH_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00780. CNH. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00036. CNH. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50219. CNH. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RUE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANDSPAKSL VDIDLSSLRD PAGIFELVEV VGNGTYGQVY KGRHVKTGQL
60 70 80 90 100
AAIKVMDVTE DEEEEIKLEI NMLKKYSHHR NIATYYGAFI KKSPPGHDDQ
110 120 130 140 150
LWLVMEFCGA GSITDLVKNT KGNTLKEDWI AYISREILRG LAHLHIHHVI
160 170 180 190 200
HRDIKGQNVL LTENAEVKLV DFGVSAQLDR TVGRRNTFIG TPYWMAPEVI
210 220 230 240 250
ACDENPDATY DYRSDLWSCG ITAIEMAEGA PPLCDMHPMR ALFLIPRNPP
260 270 280 290 300
PRLKSKKWSK KFFSFIEGCL VKNYMQRPST EQLLKHPFIR DQPNERQVRI
310 320 330 340 350
QLKDHIDRTR KKRGEKDETE YEYSGSEEEE EEVPEQEGEP SSIVNVPGES
360 370 380 390 400
TLRRDFLRLQ QENKERSEAL RRQQLLQEQQ LREQEEYKRQ LLAERQKRIE
410 420 430 440 450
QQKEQRRRLE EQQRREREAR RQQEREQRRR EQEEKRRLEE LERRRKEEEE
460 470 480 490 500
RRRAEEEKRR VEREQEYIRR QLEEEQRHLE ILQQQLLQEQ AMLLHDHRRP
510 520 530 540 550
HAQQQPPPPQ QQDRSKPSFH APEPKPHYDP ADRAREVPVR TTSRSPVLSR
560 570 580 590 600
RDSPLQGGGQ QNSQAGQRNS TSSIEPRLLW ERVEKLVPRP GSGSSSGSSN
610 620 630 640 650
SGSQPGSHPG SQSGSGERFR VRSSSKSEGS PSPRQESAAK KPDDKKEVFR
660 670 680 690 700
PLKPAGEVDL TALAKELRAV EDVRPPHKVT DYSSSSEESG TTDEEEEDVE
710 720 730 740 750
QEGADDSTSG PEDTRAASSP NLSNGETESV KTMIVHDDVE SEPAMTPSKE
760 770 780 790 800
GTLIVRQSTV DQKRASHHES NGFAGRIHLL PDLLQQSHSS STSSTSSSPS
810 820 830 840 850
SSQPTPTMSP QTPQDKLTAN ETQSASSTLQ KHKSSSSFTP FIDPRLLQIS
860 870 880 890 900
PSSGTTVTSV VGFSCDGLRP EAIRQDPTRK GSVVNVNPTN TRPQSDTPEI
910 920 930 940 950
RKYKKRFNSE ILCAALWGVN LLVGTESGLM LLDRSGQGKV YPLISRRRFQ
960 970 980 990 1000
QMDVLEGLNV LVTISGKKDK LRVYYLSWLR NKILHNDPEV EKKQGWTTVG
1010 1020 1030 1040 1050
DLEGCVHYKV VKYERIKFLV IALKSSVEVY AWAPKPYHKF MAFKSFGELL
1060 1070 1080 1090 1100
HKPLLVDLTV EEGQRLKVIY GSCAGFHAVD VDSGSVYDIY LPTHIQCSIK
1110 1120 1130 1140 1150
PHAIIILPNT DGMELLVCYE DEGVYVNTYG RITKDVVLQW GEMPTSVAYI
1160 1170 1180 1190 1200
RSNQTMGWGE KAIEIRSVET GHLDGVFMHK RAQRLKFLCE RNDKVFFASV
1210 1220
RSGGSSQVYF MTLGRTSLLS W
Length:1,221
Mass (Da):139,065
Last modified:July 1, 2008 - v1
Checksum:iFD1321E6BF52FE45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132909 Genomic DNA. No translation available.
AC166238 Genomic DNA. No translation available.
BC141109 mRNA. Translation: AAI41110.1.
RefSeqiNP_001239130.1. NM_001252201.1.
UniGeneiMm.491139.

Genome annotation databases

EnsembliENSMUST00000193682; ENSMUSP00000141862; ENSMUSG00000026074.
GeneIDi26921.
UCSCiuc011wjw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132909 Genomic DNA. No translation available.
AC166238 Genomic DNA. No translation available.
BC141109 mRNA. Translation: AAI41110.1.
RefSeqiNP_001239130.1. NM_001252201.1.
UniGeneiMm.491139.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129796.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000193682; ENSMUSP00000141862; ENSMUSG00000026074.
GeneIDi26921.
UCSCiuc011wjw.1. mouse.

Organism-specific databases

CTDi9448.
MGIiMGI:1349394. Map4k4.

Phylogenomic databases

eggNOGiKOG0587. Eukaryota.
ENOG410YBF5. LUCA.
GeneTreeiENSGT00810000125351.
HOVERGENiHBG036506.

Miscellaneous databases

ChiTaRSiMap4k4. mouse.
NextBioi304809.
SOURCEiSearch...

Family and domain databases

InterProiIPR001180. CNH_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00780. CNH. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00036. CNH. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50219. CNH. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (DEC-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB2RUE8_MOUSE
AccessioniPrimary (citable) accession number: B2RUE8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: May 11, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.