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Protein
Submitted name:

Palladin, cytoskeletal associated protein

Gene

PALLD

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Palladin, cytoskeletal associated proteinImported
Gene namesi
Name:PALLDImported
ORF Names:hCG_2026123Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142671205.

Expressioni

Gene expression databases

BgeeiENSG00000129116.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000425556.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini271 – 360Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST90
Domaini440 – 539Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST100
Domaini777 – 861Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST85
Domaini911 – 1002Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST92
Domaini1009 – 1100Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST92

Phylogenomic databases

eggNOGiENOG410IGH0. Eukaryota.
ENOG41103YT. LUCA.
HOGENOMiHOG000028074.
HOVERGENiHBG059166.

Family and domain databases

Gene3Di2.60.40.10. 6 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR033017. Palladin.
[Graphical view]
PANTHERiPTHR10489:SF741. PTHR10489:SF741. 2 hits.
PfamiPF07679. I-set. 5 hits.
[Graphical view]
SMARTiSM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
PROSITEiPS50835. IG_LIKE. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RTX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI
60 70 80 90 100
ADSETEDFDS EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST
110 120 130 140 150
PVQPLAEKQT KSISSPVSKR KPAMSPLLTR PSYIRSLRKA EKRGAKTPST
160 170 180 190 200
NVKPKTPHQR KGGPQSQLCD KAANLIEELT SIFKAAKPRN RSPNGESSSP
210 220 230 240 250
DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR HCYQDNQDLA
260 270 280 290 300
VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
310 320 330 340 350
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS
360 370 380 390 400
GSDTTSAEVF IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS
410 420 430 440 450
SPKTGVTTAV IQPLSVPVQQ VHSPTSYLCR PDGTTTAYFP PVFTKELQNT
460 470 480 490 500
AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE IQDSPDFRIL QKKPRSTAEP
510 520 530 540 550
EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS ANTENCSYES
560 570 580 590 600
MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
610 620 630 640 650
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL
660 670 680 690 700
AKPKLGFPKK ASRTARIASD EEIQGTKDAV IQDLERKLRF KEDLLNNGQP
710 720 730 740 750
RLTYEERMAR RLLGADSATV FNIQEPEEET ANQEYKVSSC EQRLISEIEY
760 770 780 790 800
RLERSPVDES GDEVQYGDVP VENGMAPFFE MKLKHYKIFE GMPVTFTCRV
810 820 830 840 850
AGNPKPKIYW FKDGKQISPK SDHYTIQRDL DGTCSLHTTA STLDDDGNYT
860 870 880 890 900
IMAANPQGRI SCTGRLMVQA VNQRGRSPRS PSGHPHVRRP RSRSRDSGDE
910 920 930 940 950
NEPIQERFFR PHFLQAPGDL TVQEGKLCRM DCKVSGLPTP DLSWQLDGKP
960 970 980 990 1000
VRPDSAHKML VRENGVHSLI IEPVTSRDAG IYTCIATNRA GQNSFSLELV
1010 1020 1030 1040 1050
VAAKEAHKPP VFIEKLQNTG VADGYPVRLE CRVLGVPPPQ IFWKKENESL
1060 1070 1080 1090 1100
THSTDRVSMH QDNHGYICLL IQGATKEDAG WYTVSAKNEA GIVSCTARLD

VYISRH
Length:1,106
Mass (Da):122,047
Last modified:July 1, 2008 - v1
Checksum:i11CC06FA94B4758B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC140850 mRNA. Translation: AAI40851.1.
CH471056 Genomic DNA. Translation: EAX04799.1.
RefSeqiNP_057165.3. NM_016081.3.
UniGeneiHs.151220.

Genome annotation databases

GeneIDi23022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC140850 mRNA. Translation: AAI40851.1.
CH471056 Genomic DNA. Translation: EAX04799.1.
RefSeqiNP_057165.3. NM_016081.3.
UniGeneiHs.151220.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000425556.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23022.

Organism-specific databases

CTDi23022.
PharmGKBiPA142671205.

Phylogenomic databases

eggNOGiENOG410IGH0. Eukaryota.
ENOG41103YT. LUCA.
HOGENOMiHOG000028074.
HOVERGENiHBG059166.

Miscellaneous databases

ChiTaRSiPALLD. human.
GenomeRNAii23022.

Gene expression databases

BgeeiENSG00000129116.

Family and domain databases

Gene3Di2.60.40.10. 6 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR033017. Palladin.
[Graphical view]
PANTHERiPTHR10489:SF741. PTHR10489:SF741. 2 hits.
PfamiPF07679. I-set. 5 hits.
[Graphical view]
SMARTiSM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
PROSITEiPS50835. IG_LIKE. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB2RTX2_HUMAN
AccessioniPrimary (citable) accession number: B2RTX2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: November 30, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.