Ugt1a5

Protein namesⁱ	Recommended name: UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesⁱ	Name:Ugt1a5Imported ORF Names:mCG_14318Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 1

Organism-specific databases

MGIⁱ	MGI:3032634. Ugt1a5.

Subcellular locationⁱ

Membrane
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU362059
; Single-pass membrane protein
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU362059

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	487 – 510	HelicalUniRule annotationAdd BLAST		24

GO - Cellular componentⁱ

endoplasmic reticulum Source: MGI
integral component of membrane Source: UniProtKB-UniRule
intracellular membrane-bounded organelle Source: GO_Central

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 24	UniRule annotationAdd BLAST		24
ChainⁱPRO_5010595713	25 – 529	UDP-glucuronosyltransferaseUniRule annotationAdd BLAST		505

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000089943.

Bgeeⁱ

ENSMUSG00000089943.

Interactionⁱ

GO - Molecular functionⁱ

enzyme binding Source: MGI
protein heterodimerization activity Source: MGI
protein homodimerization activity Source: MGI

Complete GO annotation...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000095263.

STRINGⁱ

10090.ENSMUSP00000095263.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the UDP-glycosyltransferase family.UniRule annotation

Keywords - Domainⁱ

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1192. Eukaryota. COG1819. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118949.
HOGENOMⁱ	HOG000220832.
HOVERGENⁱ	HBG004033.
KEGG Orthology (KO) More...KOⁱ	K00699.
OMAⁱ	IHRSCVE.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G03YY.
TreeFamⁱ	TF315472.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002213. UDP_glucos_trans.
PANTHERⁱ	PTHR11926. PTHR11926. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00201. UDPGT. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00375. UDPGT. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

B2RT14-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGLRMPLQGL VGLLLLCALP WTEGEKVLVF PVGGSHWLSM RDVVRELHAQ 
        60         70         80         90        100
GHQTVVLAPE VNMRIKEEDF FTFKVYAVPY TRQELEEMME NLKVFFDTGN 
       110        120        130        140        150
YMKKIFKTSE ALRNMSTVLL KTCTNILHNE SLLHHLNSSS FDVVFTDPVF 
       160        170        180        190        200
PCGALLAKYL GIPAVFFLRY IPCGIEYEAT QCPSPSSYIP NLFTRLSDHM 
       210        220        230        240        250
DFLQRVQNML YHLVLKYICH LLITPYESLA SELFQREVSS VELFSYASVW 
       260        270        280        290        300
LFRGDFVLDY PRPIMPNMVF IGGINCVTKK PLSQEFEAYV NASGEHGIVV 
       310        320        330        340        350
FSLGSMVSEI PEKKAMEIAE ALGRIPQTVL WRYTGTRPSN LAKNTILVKW 
       360        370        380        390        400
LPQNDLLGHP KTRAFITHSG SHGIYEGICN GVPMVMMPLF GDQMDNAKRM 
       410        420        430        440        450
ETRGAGVTLN VLEMTADDLE NALKTVINNK SYKENIMRLS SLHKDRPIEP 
       460        470        480        490        500
LDLAVFWVEY VMRHKGAPHL RPAAHDLTWY QYHSLDVIGF LLAIVLTVVF 
       510        520 
IVFKCCAYGC RKCFGGKGRV KKSHKSKTH

Length:529

Mass (Da):60,073

Last modified:July 1, 2008 - v1

Checksum:ⁱACA1EADA382CCE4A

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC087780 Genomic DNA. No translation available. AC087801 Genomic DNA. No translation available. BC139093 mRNA. Translation: AAI39094.1. BC139094 mRNA. Translation: AAI39095.1. CH466520 Genomic DNA. Translation: EDL40128.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_964005.2. NM_201643.2.
UniGeneⁱ	Mm.300095.

Genome annotation databases

Ensemblⁱ	ENSMUST00000097659; ENSMUSP00000095263; ENSMUSG00000089943.
GeneIDⁱ	394433.
KEGGⁱ	mmu:394433.
UCSC genome browser More...UCSCⁱ	uc007byh.1. mouse.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC087780 Genomic DNA. No translation available. AC087801 Genomic DNA. No translation available. BC139093 mRNA. Translation: AAI39094.1. BC139094 mRNA. Translation: AAI39095.1. CH466520 Genomic DNA. Translation: EDL40128.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_964005.2. NM_201643.2.
UniGeneⁱ	Mm.300095.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000095263.

STRINGⁱ

10090.ENSMUSP00000095263.

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	394433.
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000097659; ENSMUSP00000095263; ENSMUSG00000089943.
GeneIDⁱ	394433.
KEGGⁱ	mmu:394433.
UCSC genome browser More...UCSCⁱ	uc007byh.1. mouse.

Organism-specific databases

CTDⁱ	54579.
MGIⁱ	MGI:3032634. Ugt1a5.

Phylogenomic databases

eggNOGⁱ	KOG1192. Eukaryota. COG1819. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118949.
HOGENOMⁱ	HOG000220832.
HOVERGENⁱ	HBG004033.
KEGG Orthology (KO) More...KOⁱ	K00699.
OMAⁱ	IHRSCVE.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G03YY.
TreeFamⁱ	TF315472.

Enzyme and pathway databases

Reactomeⁱ	R-MMU-156588. Glucuronidation. R-MMU-189483. Heme degradation.

Reactomeⁱ

R-MMU-156588. Glucuronidation.
R-MMU-189483. Heme degradation.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000089943.

Bgeeⁱ

ENSMUSG00000089943.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002213. UDP_glucos_trans.
PANTHERⁱ	PTHR11926. PTHR11926. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00201. UDPGT. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00375. UDPGT. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B2RT14_MOUSE
Accessionⁱ	B2RT14Primary (citable) accession number: B2RT14
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 1, 2008
	Last sequence update:	July 1, 2008
	Last modified:	July 5, 2017
	This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B2RT14 (B2RT14_MOUSE)

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UDP-glucuronosyltransferase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ