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B2RSN1

- B2RSN1_MOUSE

UniProt

B2RSN1 - B2RSN1_MOUSE

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Protein
Submitted name: Myelocytomatosis oncogene
Gene
Myc
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. core promoter proximal region sequence-specific DNA binding Source: MGI
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. B cell apoptotic process Source: MGI
  2. Wnt signaling pathway Source: MGI
  3. activation of cysteine-type endopeptidase activity involved in apoptotic process Source: MGI
  4. canonical Wnt signaling pathway involved in negative regulation of apoptotic process Source: MGI
  5. canonical Wnt signaling pathway involved in positive regulation of apoptotic process Source: MGI
  6. cellular response to DNA damage stimulus Source: MGI
  7. detection of mechanical stimulus involved in sensory perception of sound Source: MGI
  8. intrinsic apoptotic signaling pathway in response to DNA damage Source: MGI
  9. middle ear morphogenesis Source: MGI
  10. negative regulation of protein binding Source: MGI
  11. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  12. pigmentation Source: MGI
  13. positive regulation of B cell apoptotic process Source: MGI
  14. positive regulation of apoptotic signaling pathway Source: MGI
  15. positive regulation of catalytic activity Source: MGI
  16. positive regulation of cell proliferation Source: MGI
  17. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  18. protein processing Source: MGI
  19. regulation of apoptotic process Source: MGI
  20. regulation of gene expression Source: MGI
  21. regulation of transcription, DNA-templated Source: MGI
  22. response to alkaloid Source: MGI
  23. response to radiation Source: MGI
  24. skeletal muscle cell differentiation Source: MGI
  25. skeletal system morphogenesis Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Myelocytomatosis oncogeneImported
Gene namesi
Name:MycImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97250. Myc.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: MGI
  2. nuclear body Source: MGI
  3. nucleus Source: MGI
  4. spindle Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriB2RSN1.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022971.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000043075.
HOVERGENiHBG000472.
InParanoidiB2RSN1.
KOiK04377.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR003327. Myc-LZ.
IPR002418. Tscrpt_reg_Myc.
IPR012682. Tscrpt_reg_Myc_N.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
PF02344. Myc-LZ. 1 hit.
PF01056. Myc_N. 1 hit.
[Graphical view]
PIRSFiPIRSF001705. Myc_protein. 1 hit.
PRINTSiPR00044. LEUZIPPRMYC.
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RSN1-1 [UniParc]FASTAAdd to Basket

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MDFLWALETP QTATTMPLNV NFTNRNYDLD YDSVQPYFIC DEEENFYHQQ    50
QQSELQPPAP SEDIWKKFEL LPTPPLSPSR RSGLCSPSYV AVATSFSPRE 100
DDDGGGGNFS TADQLEMMTE LLGGDMVNQS FICDPDDETF IKNIIIQDCM 150
WSGFSAAAKL VSEKLASYQA ARKDSTSLSP ARGHSVCSTS SLYLQDLTAA 200
ASECIDPSVV FPYPLNDSSS PKSCTSSDST AFSPSSDSLL SSESSPRASP 250
EPLVLHEETP PTTSSDSEEE QEDEEEIDVV SVEKRQTPAK RSESGSSPSR 300
GHSKPPHSPL VLKRCHVSTH QHNYAAPPST RKDYPAAKRA KLDSGRVLKQ 350
ISNNRKCSSP RSSDTEENDK RRTHNVLERQ RRNELKRSFF ALRDQIPELE 400
NNEKAPKVVI LKKATAYILS IQADEHKLTS EKDLLRKRRE QLKHKLEQLR 450
NSGA 454
Length:454
Mass (Da):50,678
Last modified:July 1, 2008 - v1
Checksum:i1CE6F658565FF720
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC138931 mRNA. Translation: AAI38932.1.
BC138932 mRNA. Translation: AAI38933.1.
RefSeqiNP_001170823.1. NM_001177352.1.
NP_034979.3. NM_010849.4.
UniGeneiMm.2444.

Genome annotation databases

GeneIDi17869.
KEGGimmu:17869.
UCSCiuc007vyg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC138931 mRNA. Translation: AAI38932.1 .
BC138932 mRNA. Translation: AAI38933.1 .
RefSeqi NP_001170823.1. NM_001177352.1.
NP_034979.3. NM_010849.4.
UniGenei Mm.2444.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000022971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 17869.
KEGGi mmu:17869.
UCSCi uc007vyg.1. mouse.

Organism-specific databases

CTDi 4609.
MGIi MGI:97250. Myc.

Phylogenomic databases

HOGENOMi HOG000043075.
HOVERGENi HBG000472.
InParanoidi B2RSN1.
KOi K04377.

Miscellaneous databases

ChiTaRSi MYC. mouse.
NextBioi 292641.
PROi B2RSN1.
SOURCEi Search...

Gene expression databases

Genevestigatori B2RSN1.

Family and domain databases

Gene3Di 4.10.280.10. 1 hit.
InterProi IPR011598. bHLH_dom.
IPR003327. Myc-LZ.
IPR002418. Tscrpt_reg_Myc.
IPR012682. Tscrpt_reg_Myc_N.
[Graphical view ]
Pfami PF00010. HLH. 1 hit.
PF02344. Myc-LZ. 1 hit.
PF01056. Myc_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF001705. Myc_protein. 1 hit.
PRINTSi PR00044. LEUZIPPRMYC.
SMARTi SM00353. HLH. 1 hit.
[Graphical view ]
SUPFAMi SSF47459. SSF47459. 1 hit.
PROSITEi PS50888. BHLH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.

Entry informationi

Entry nameiB2RSN1_MOUSE
AccessioniPrimary (citable) accession number: B2RSN1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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