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Protein
Submitted name:

Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)

Gene

Mpp5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)Imported
Gene namesi
Name:Mpp5Imported
ORF Names:mCG_5801Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1927339 Mpp5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000021112

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 177L27InterPro annotationAdd BLAST58
Domaini179 – 235L27InterPro annotationAdd BLAST57
Domaini256 – 336PDZInterPro annotationAdd BLAST81
Domaini345 – 417SH3InterPro annotationAdd BLAST73
Domaini479 – 660Guanylate kinase-likeInterPro annotationAdd BLAST182

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili53 – 76Sequence analysisAdd BLAST24
Coiled coili645 – 665Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the MAGUK family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0609 Eukaryota
COG0194 LUCA
HOVERGENiHBG001858
KOiK06091
OMAiVHQKEGQ
OrthoDBiEOG091G065I

Family and domain databases

CDDicd12036 SH3_MPP5, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR014775 L27_C
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR015145 L27_N
IPR031185 MPP5
IPR035601 MPP5_SH3
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR23122:SF61 PTHR23122:SF61, 1 hit
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF02828 L27, 1 hit
PF09060 L27_N, 1 hit
PF00595 PDZ, 1 hit
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM00569 L27, 2 hits
SM00228 PDZ, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF101288 SSF101288, 2 hits
SSF50044 SSF50044, 1 hit
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS51022 L27, 2 hits
PS50106 PDZ, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

B2RRY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTSYMNGHV TEESDSGIKN LDLASPEEYP KHREMAVDCP GDLGTRMMPV
60 70 80 90 100
RRSAQLERIR QQQEDMRRRR EEEGKKQELD LNSSMRLKKL AQIPPKTGID
110 120 130 140 150
NPIFDTEEGI VLESPHYAVN ILDVEDLFSS LKHIQHTLVD SQSQEDISLL
160 170 180 190 200
LQLVQNRDFQ NAFKIHNAVT VHMSKASPPF PLIANVQDLV QEVQTVLKPV
210 220 230 240 250
HQKEGQELTA LLNAPHIQAL LLAHDKVAEQ EMQLEPITDE RVYESIGHYG
260 270 280 290 300
GETVKIVRIE KARDIPLGAT VRNEMDSVII SRIVKGGAAE KSGLLHEGDE
310 320 330 340 350
VLEINGIEIR GKDVNEVFDL LSDMHGTLTF VLIPSQQIKP PPAKETVIHV
360 370 380 390 400
KAHFDYDPSD DPYVPCRELG LSFQKGDILH VISQEDPNWW QAYREGDEDN
410 420 430 440 450
QPLAGLVPGK SFQQQREAMK QTIEEDKEPE KSGKLWCAKK NKKKRKKVLY
460 470 480 490 500
NANKNDDYDN EEILTYEEMS LYHQPANRKR PIILIGPQNC GQNELRQRLM
510 520 530 540 550
NKEKDRFASA VPHTTRNRRD HEVAGRDYHF VSRQAFEADI AAGKFIEHGE
560 570 580 590 600
FEKNLYGTSI DSVRQVINSG KICLLSLRTQ SLKTLRNSDL KPYIIFIAPP
610 620 630 640 650
SQERLRALLA KEGKNPKPEE LREIIEKTRE MEQNNGHYFD TAIVNSDLDK
660 670
AYQELLRLIN KLDTEPQWVP STWLR
Length:675
Mass (Da):77,229
Last modified:July 1, 2008 - v1
Checksum:i66670F919F18063B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138624 mRNA Translation: AAI38625.1
CH466590 Genomic DNA Translation: EDL02623.1
RefSeqiNP_062525.1, NM_019579.3
XP_006516160.1, XM_006516097.3
UniGeneiMm.425777

Genome annotation databases

GeneIDi56217
KEGGimmu:56217

Similar proteinsi

Entry informationi

Entry nameiB2RRY4_MOUSE
AccessioniPrimary (citable) accession number: B2RRY4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 25, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health