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B2RQX9

- B2RQX9_MOUSE

UniProt

B2RQX9 - B2RQX9_MOUSE

Protein

Transporter

Gene

Slc6a5

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (01 Jul 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. neurotransmitter:sodium symporter activity Source: InterPro

    Keywords - Biological processi

    SymportUniRule annotationSAAS annotation, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    TransporterUniRule annotation
    Gene namesi
    Name:Slc6a5Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:105090. Slc6a5.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriB2RQX9.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the sodium:neurotransmitter symporter (SNF) family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115427.
    HOVERGENiHBG071421.
    InParanoidiB2RQX9.
    KOiK05038.
    OMAiGNALHCK.
    OrthoDBiEOG793B71.
    TreeFamiTF343812.

    Family and domain databases

    InterProiIPR000175. Na/ntran_symport.
    [Graphical view]
    PANTHERiPTHR11616. PTHR11616. 1 hit.
    PfamiPF00209. SNF. 1 hit.
    [Graphical view]
    PRINTSiPR00176. NANEUSMPORT.
    PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
    PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
    PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2RQX9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKQPANILE AAVPGHRDSP RAPRTSPEQD LPAEAPTATV QPPRVPRSAS    50
    TGAQTFQSAD ARACEAQQSG VGFCNLSSPR AQATSAALRD LSEGHSAQAN 100
    PPSGPAGAGN ALHCKIPALR GPEEDANVSV GKGTLEHNNT PAVGWVNMSQ 150
    STVVLGTDGI ASVLPGSVAT TTIPEDEQGD ENKARGNWSS KLDFILSMVG 200
    YAVGLGNVWR FPYLAFQNGG GAFLIPYLMM LALAGLPIFF LEVSLGQFAS 250
    QGPVSVWKAI PALQGCGIAM LIISVLIAIY YNVIICYTLF YLFASFVSVL 300
    PWGSCNNPWN TPECKDKTKL LLDSCVIGDH PKIQIKNSTF CMTAYPNLTM 350
    VNFTSQTNKT FVSGSEEYFK YFVLKISAGI EYPGEIRWPL AFCLFLAWVI 400
    VYASLAKGIK SSGKVVYFTA TFPYVVLVIL LIRGVTLPGA GAGIWYFITP 450
    KWEKLTDATV WKDAATQIFF SLSAAWGGLI TLSSYNKFHN NCYRDTLIVT 500
    CTNSATSIFA GFVIFSVIGF MANERKVNIE NVADQGPGIA FVVYPEALTR 550
    LPLSPFWAII FFLMLLTLGL DTMFATIETI VTSISDEFPK YLRTHKPVFT 600
    LGCCICFFIM GFPMITQGGI YMFQLVDTYA ASYALVIIAI FELVGISYVY 650
    GLQRFCEDIE MMIGFKPNIF WKVCWAFVTP TILTFILCFS FYQWEPMTYG 700
    SYRYPNWSMV LGWLMLACSV IWIPIMFVIK MYLAPGRFIE RLKLVCSPQP 750
    DWGPFLAQHR GERYKNMIDP LGTSSLGLKL PVKDLELGTQ C 791
    Length:791
    Mass (Da):87,029
    Last modified:July 1, 2008 - v1
    Checksum:i3400501C93EC4421
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC116694 Genomic DNA. No translation available.
    AC135354 Genomic DNA. No translation available.
    BC138125 mRNA. Translation: AAI38126.1.
    BC138126 mRNA. Translation: AAI38127.1.
    RefSeqiNP_001139485.1. NM_001146013.1.
    NP_683733.2. NM_148931.3.
    XP_006540610.1. XM_006540547.1.
    UniGeneiMm.207053.

    Genome annotation databases

    EnsembliENSMUST00000056442; ENSMUSP00000058699; ENSMUSG00000039728.
    ENSMUST00000107605; ENSMUSP00000103230; ENSMUSG00000039728.
    GeneIDi104245.
    KEGGimmu:104245.
    UCSCiuc009hbv.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC116694 Genomic DNA. No translation available.
    AC135354 Genomic DNA. No translation available.
    BC138125 mRNA. Translation: AAI38126.1 .
    BC138126 mRNA. Translation: AAI38127.1 .
    RefSeqi NP_001139485.1. NM_001146013.1.
    NP_683733.2. NM_148931.3.
    XP_006540610.1. XM_006540547.1.
    UniGenei Mm.207053.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000056442 ; ENSMUSP00000058699 ; ENSMUSG00000039728 .
    ENSMUST00000107605 ; ENSMUSP00000103230 ; ENSMUSG00000039728 .
    GeneIDi 104245.
    KEGGi mmu:104245.
    UCSCi uc009hbv.2. mouse.

    Organism-specific databases

    CTDi 9152.
    MGIi MGI:105090. Slc6a5.

    Phylogenomic databases

    GeneTreei ENSGT00740000115427.
    HOVERGENi HBG071421.
    InParanoidi B2RQX9.
    KOi K05038.
    OMAi GNALHCK.
    OrthoDBi EOG793B71.
    TreeFami TF343812.

    Miscellaneous databases

    NextBioi 356802.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori B2RQX9.

    Family and domain databases

    InterProi IPR000175. Na/ntran_symport.
    [Graphical view ]
    PANTHERi PTHR11616. PTHR11616. 1 hit.
    Pfami PF00209. SNF. 1 hit.
    [Graphical view ]
    PRINTSi PR00176. NANEUSMPORT.
    PROSITEi PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
    PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
    PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB2RQX9_MOUSE
    AccessioniPrimary (citable) accession number: B2RQX9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 2008
    Last sequence update: July 1, 2008
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3