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B2RQX9

- B2RQX9_MOUSE

UniProt

B2RQX9 - B2RQX9_MOUSE

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Protein

Transporter

Gene
Slc6a5
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. neurotransmitter:sodium symporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

SymportUniRule annotationSAAS annotations, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:Slc6a5Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:105090. Slc6a5.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriB2RQX9.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000115427.
HOVERGENiHBG071421.
InParanoidiB2RQX9.
KOiK05038.
OMAiGNALHCK.
OrthoDBiEOG793B71.
TreeFamiTF343812.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RQX9-1 [UniParc]FASTAAdd to Basket

« Hide

MNKQPANILE AAVPGHRDSP RAPRTSPEQD LPAEAPTATV QPPRVPRSAS    50
TGAQTFQSAD ARACEAQQSG VGFCNLSSPR AQATSAALRD LSEGHSAQAN 100
PPSGPAGAGN ALHCKIPALR GPEEDANVSV GKGTLEHNNT PAVGWVNMSQ 150
STVVLGTDGI ASVLPGSVAT TTIPEDEQGD ENKARGNWSS KLDFILSMVG 200
YAVGLGNVWR FPYLAFQNGG GAFLIPYLMM LALAGLPIFF LEVSLGQFAS 250
QGPVSVWKAI PALQGCGIAM LIISVLIAIY YNVIICYTLF YLFASFVSVL 300
PWGSCNNPWN TPECKDKTKL LLDSCVIGDH PKIQIKNSTF CMTAYPNLTM 350
VNFTSQTNKT FVSGSEEYFK YFVLKISAGI EYPGEIRWPL AFCLFLAWVI 400
VYASLAKGIK SSGKVVYFTA TFPYVVLVIL LIRGVTLPGA GAGIWYFITP 450
KWEKLTDATV WKDAATQIFF SLSAAWGGLI TLSSYNKFHN NCYRDTLIVT 500
CTNSATSIFA GFVIFSVIGF MANERKVNIE NVADQGPGIA FVVYPEALTR 550
LPLSPFWAII FFLMLLTLGL DTMFATIETI VTSISDEFPK YLRTHKPVFT 600
LGCCICFFIM GFPMITQGGI YMFQLVDTYA ASYALVIIAI FELVGISYVY 650
GLQRFCEDIE MMIGFKPNIF WKVCWAFVTP TILTFILCFS FYQWEPMTYG 700
SYRYPNWSMV LGWLMLACSV IWIPIMFVIK MYLAPGRFIE RLKLVCSPQP 750
DWGPFLAQHR GERYKNMIDP LGTSSLGLKL PVKDLELGTQ C 791
Length:791
Mass (Da):87,029
Last modified:July 1, 2008 - v1
Checksum:i3400501C93EC4421
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC116694 Genomic DNA. No translation available.
AC135354 Genomic DNA. No translation available.
BC138125 mRNA. Translation: AAI38126.1.
BC138126 mRNA. Translation: AAI38127.1.
RefSeqiNP_001139485.1. NM_001146013.1.
NP_683733.2. NM_148931.3.
XP_006540610.1. XM_006540547.1.
UniGeneiMm.207053.

Genome annotation databases

EnsembliENSMUST00000056442; ENSMUSP00000058699; ENSMUSG00000039728.
ENSMUST00000107605; ENSMUSP00000103230; ENSMUSG00000039728.
GeneIDi104245.
KEGGimmu:104245.
UCSCiuc009hbv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC116694 Genomic DNA. No translation available.
AC135354 Genomic DNA. No translation available.
BC138125 mRNA. Translation: AAI38126.1 .
BC138126 mRNA. Translation: AAI38127.1 .
RefSeqi NP_001139485.1. NM_001146013.1.
NP_683733.2. NM_148931.3.
XP_006540610.1. XM_006540547.1.
UniGenei Mm.207053.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000056442 ; ENSMUSP00000058699 ; ENSMUSG00000039728 .
ENSMUST00000107605 ; ENSMUSP00000103230 ; ENSMUSG00000039728 .
GeneIDi 104245.
KEGGi mmu:104245.
UCSCi uc009hbv.2. mouse.

Organism-specific databases

CTDi 9152.
MGIi MGI:105090. Slc6a5.

Phylogenomic databases

GeneTreei ENSGT00740000115427.
HOVERGENi HBG071421.
InParanoidi B2RQX9.
KOi K05038.
OMAi GNALHCK.
OrthoDBi EOG793B71.
TreeFami TF343812.

Miscellaneous databases

NextBioi 356802.
SOURCEi Search...

Gene expression databases

Genevestigatori B2RQX9.

Family and domain databases

InterProi IPR000175. Na/ntran_symport.
[Graphical view ]
PANTHERi PTHR11616. PTHR11616. 1 hit.
Pfami PF00209. SNF. 1 hit.
[Graphical view ]
PRINTSi PR00176. NANEUSMPORT.
PROSITEi PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB2RQX9_MOUSE
AccessioniPrimary (citable) accession number: B2RQX9
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 16, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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