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Protein
Submitted name:

Dopamine receptor 5

Gene

Drd5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Dopamine receptor 5Imported
Gene namesi
Name:Drd5Imported
ORF Names:mCG_61530Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:94927 Drd5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei39 – 64HelicalSequence analysisAdd BLAST26
Transmembranei76 – 93HelicalSequence analysisAdd BLAST18
Transmembranei113 – 134HelicalSequence analysisAdd BLAST22
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Transmembranei219 – 242HelicalSequence analysisAdd BLAST24
Transmembranei288 – 308HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000039358
ExpressionAtlasiB2RQS5 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 354G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST300

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
HOVERGENiHBG106962
KOiK05840
OMAiVWELDCE
OrthoDBiEOG091G06VI

Family and domain databases

InterProiView protein in InterPro
IPR000497 Dopamine_D5_rcpt
IPR000929 Dopamine_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PANTHERiPTHR43893:SF8 PTHR43893:SF8, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00566 DOPAMINED1BR
PR00242 DOPAMINER
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

B2RQS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPPGRNGTA HRARLGLQRQ LAQVDAPGGS AAPLGPAQVV TAGLLTLLIV
60 70 80 90 100
WTLLGNVLVC AAIVRSRHLR AKMTNIFIVS LAVSDLFVAL LVMPWKAVAE
110 120 130 140 150
VAGYWPFGAF CDIWVAFDIM CSTASILNLC IISVDRYWAI SRPFRYERKM
160 170 180 190 200
TQRVALVMVA LAWTLSILIS FIPVQLNWHR DKAGSQGREG LLSNETPWEE
210 220 230 240 250
GWELDGRTEN CDSSLNRTYA ISSSLISFYI PVAIMIVTYT RIYRIAQVQI
260 270 280 290 300
RRISSLERAA EHAQSCRSRG ACEPDPSLRA SIKKETKVFK TLSVIMGVFV
310 320 330 340 350
CCWLPFFILN CMVPFCSSGD AQGPRTGFPC VSETTFDIFV WFGWANSSLN
360 370 380 390 400
PIIYAFNADF RKVFAQLLGC SHLCFRTPVQ TVNISNELIS YNQDTVFHRE
410 420 430 440 450
IAAAYVHMIP NAVSSGDREV GEEEEAEEEG PFDHMSQISP TTPDGDLAAE
460 470
SVWELDCEEE VSLGKISPLT PNCFHKTA
Length:478
Mass (Da):53,076
Last modified:July 1, 2008 - v1
Checksum:iD39165BC558131DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138059 mRNA Translation: AAI38060.1
BC138060 mRNA Translation: AAI38061.1
CH466524 Genomic DNA Translation: EDL37553.1
RefSeqiNP_038531.1, NM_013503.3
UniGeneiMm.167154

Genome annotation databases

GeneIDi13492
KEGGimmu:13492

Similar proteinsi

Entry informationi

Entry nameiB2RQS5_MOUSE
AccessioniPrimary (citable) accession number: B2RQS5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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