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Protein

UvrABC system protein C

Gene

uvrC

Organism
Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:PGN_1938
OrganismiPorphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Taxonomic identifieri431947 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas
Proteomesi
  • UP000008842 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000995061 – 600UvrABC system protein CAdd BLAST600

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi431947.PGN_1938.

Structurei

3D structure databases

SMRiB2RM62.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 94GIY-YIGUniRule annotationAdd BLAST79
Domaini208 – 243UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII. Bacteria.
COG0322. LUCA.
HOGENOMiHOG000279960.
KOiK03703.
OMAiLFPIRQC.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR010994. RuvA_2-like.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

B2RM62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTRDELNII LPTLPEKPGC YQYFDEDGKV IYVGKAKNLR RRVSSYFYKE
60 70 80 90 100
HADRKTRILV RQIRSIKYIV VDSEGDALLL ENSLIKEYQP RYNVLLKDGK
110 120 130 140 150
TYPSIVIKRE PFPRIFATRD IKKDGSEYFG PYPGALIAKG MLRLVKEIYP
160 170 180 190 200
IRTCKLDLRE EKIRQGRYRV CLQYHIKKCK GPCIGNQTSN EYESNVSEIR
210 220 230 240 250
DLLRGNLHRL VRMYRDRMQA YSEELRFEEA QICKERIELL ERYEAKHTVV
260 270 280 290 300
PRNIDNVDVF SYDEDEHTAY INYMHIEHGG INRVYTLEYR KQIEESKEEL
310 320 330 340 350
LAAAITELRQ RFESNAHEIV LPFDTGWQTG ESITTTIPRR GDKRKLLELS
360 370 380 390 400
EKNVAQYKLD KLKRAEKLNP EQRALHIVHG IQKDLHLDRP PKHIECFDNS
410 420 430 440 450
NIQGTSPVAA CVVFKMGKPS KKDYRKFHVK TVEGPNDFAS MREIISRHYT
460 470 480 490 500
RLTEENLPLP DLIVVDGGKG QLSAAYETLD KLGLIGKIPI IGLAERLEEI
510 520 530 540 550
FFPKDPVPLI LDKKSETLKV IQHLRDEAHR FGIGFHRDVR SKKQIQSELD
560 570 580 590 600
NIKGIGKKTK EDLLRHFKSV KRIRSAEEEE LSALIGRNKA KLLYEGLRKK
Length:600
Mass (Da):69,978
Last modified:July 1, 2008 - v1
Checksum:iDF9F7DE471B70484
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009380 Genomic DNA. Translation: BAG34457.1.

Genome annotation databases

EnsemblBacteriaiBAG34457; BAG34457; PGN_1938.
KEGGipgn:PGN_1938.

Similar proteinsi

Entry informationi

Entry nameiUVRC_PORG3
AccessioniPrimary (citable) accession number: B2RM62
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: October 25, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families