B2RM04 (B2RM04_PORG3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Malate dehydrogenase EMBL BAG34399.1

Gene names

Ordered Locus Names:

PGN_1880

Organism

Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) [Complete proteome] [HAMAP]

Taxonomic identifier

431947 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the LDH/MDH superfamily. RuleBase RU003369

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle SAAS SAAS010945
Ligand	NAD SAAS SAAS010945
Molecular function	Oxidoreductase RuleBase RU003369
Technical term	3D-structure PDB 3FI9 Complete proteome
Gene Ontology (GO)
Biological process	cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro malate metabolic process Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase activity Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2RM04 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 0F6B51144E82970C	FASTA	334	36,161
	10 20 30 40 50 60 MSYLTEEKLT IVGAAGMIGS NMAQTAAMMR LTPNLCLYDP FAVGLEGVAE EIRHCGFEGL 70 80 90 100 110 120 NLTFTSDIKE ALTDAKYIVS SGGAPRKEGM TREDLLKGNA EIAAQLGKDI KSYCPDCKHV 130 140 150 160 170 180 IIIFNPADIT GLVTLIYSGL KPSQVTTLAG LDSTRLQSEL AKHFGIKQSL VTNTRTYGGH 190 200 210 220 230 240 GEQMAVFAST AKVNGTPLTD LIGTDKLTNE QWAELKQRVV KGGANIIKLR GRSSFQSPSY 250 260 270 280 290 300 VSIEMIRAAM GGEAFRWPAG CYVNVPGFEH IMMAMETTIT KDGVKHSDIN QLGNEAERAA 310 320 330 LKESYSHLAK LRDEVIAMGI IPAIADWKTV NPNL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis." Naito M., Hirakawa H., Yamashita A., Ohara N., Shoji M., Yukitake H., Nakayama K., Toh H., Yoshimura F., Kuhara S., Hattori M., Hayashi T., Nakayama K. DNA Res. 15:215-225(2008) [PubMed: 18524787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33277 / DSM 20709 / JCM 12257.
[2]	"Crystal structure of malate dehydrogenase from Porphyromonas gingivalis." Bonanno J.B., Freeman J., Bain K.T., Miller S., Romero R., Wasserman S., Sauder J.M., Burley S.K., Almo S.C. Submitted (DEC-2008) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 2-333.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AP009380 Genomic DNA. Translation: BAG34399.1.

RefSeq

YP_001929996.1. NC_010729.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3FI9	X-ray	1.90	A/B	2-333	[»]

ProteinModelPortal

B2RM04.

ModBase

Search...

Protein-protein interaction databases

STRING

B2RM04.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

6330184.

GenomeReviews

Gene locus PGN_1880 in contig AP009380_GR.

KEGG

pgn:PGN_1880.

PATRIC

22976723. VBIPorGin26334_1851.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

HBG347324.

OMA

DPNVAFK.

ProtClustDB

CLSK823181.

Family and domain databases

InterPro

IPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR010945. Malate_DH_type2.
IPR016040. NAD(P)-bd_dom.
[Graphical view]

Gene3D

G3DSA:3.90.110.10. lact_mal_DH. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.

KO

K00024.

PANTHER

PTHR23382. MDH_SF1. 1 hit.

Pfam

PF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]

PIRSF

PIRSF000102. Lac_mal_DH. 1 hit.

SUPFAM

SSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.

ProtoNet

Search...

Entry information

Entry name

B2RM04_PORG3

Accession

Primary (citable) accession number: B2RM04

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)