B2RLW6 (RS4_PORG3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	PGN_1842

Organism

Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) [Complete proteome] [HAMAP]

Taxonomic identifier

431947 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP MF_01306_B With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP MF_01306_B
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	30S ribosomal protein S4 HAMAP MF_01306_B		PRO_1000140773
Regions
	Domain	92 – 154	63	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	B2RLW6 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: AE85809E84C8F110	FASTA	201	22,927
	10 20 30 40 50 60 MARYTGPKSK IARKFGDPIF GADKVLSKKN YPPGQHGNNR RRKTSEYGLQ LREKQKAKYT 70 80 90 100 110 120 YGVLEKQFRH LFHRAQRAKG VTGELLIQFL EARLDNVVFR LGIAPTRSAA RQLVSHRHIT 130 140 150 160 170 180 VDGSVVNIPS YSVKPGQVIG VRERSKSLEV IADALTGFNH SKYPWMEWDQ SSLSGKLLHM 190 200 PDRTDIPENI KEQLIVELYS K

References

[1]

"Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis." Naito M., Hirakawa H., Yamashita A., Ohara N., Shoji M., Yukitake H., Nakayama K., Toh H., Yoshimura F., Kuhara S., Hattori M., Hayashi T., Nakayama K. DNA Res. 15:215-225(2008) [PubMed: 18524787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33277 / DSM 20709 / JCM 12257.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009380 Genomic DNA. Translation: BAG34361.1.
RefSeq	YP_001929958.1. NC_010729.1.
3D structure databases
ProteinModelPortal	B2RLW6.
SMR	B2RLW6. Positions 43-201.
ModBase	Search...
Protein-protein interaction databases
STRING	B2RLW6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6329567.
GenomeReviews	Gene locus PGN_1842 in contig AP009380_GR.
KEGG	pgn:PGN_1842.
PATRIC	22976645. VBIPorGin26334_1812.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285740.
OMA	QLVVELY.
ProtClustDB	PRK05327.
Family and domain databases
HAMAP	MF_01306_B. Ribosomal_S4_B. [Tree]
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.1050.10. G3DSA:1.10.1050.10. 1 hit. G3DSA:3.10.290.10. G3DSA:3.10.290.10. 1 hit.
KO	K02986.
PANTHER	PTHR11831. Ribosomal_S4. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. RpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_PORG3

Accession

Primary (citable) accession number: B2RLW6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program