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B2RLG9 (ALF1_PORG3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Fructose-bisphosphate aldolase class 1

EC=4.1.2.13
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name=FBP aldolase
Gene names
Name:fda
Ordered Locus Names:PGN_1695
OrganismPorphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) [Complete proteome] [HAMAP]
Taxonomic identifier431947 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas

Protein attributes

Sequence length293 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. HAMAP-Rule MF_00729

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. HAMAP-Rule MF_00729

Sequence similarities

Belongs to the class I fructose-bisphosphate aldolase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionfructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 293293Fructose-bisphosphate aldolase class 1 HAMAP-Rule MF_00729
PRO_1000132711

Sites

Active site1761Proton acceptor By similarity
Active site2111Schiff-base intermediate with dihydroxyacetone-P By similarity

Sequences

Sequence LengthMass (Da)Tools
B2RLG9 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: CDBA3CFF649DCE91

FASTA29332,987
        10         20         30         40         50         60 
MNKEQLQQMR QAPGFVGALD QSGGSTPKAL KAYGIQPDAY QSEEEMFDLI HQMRTRMITS 

        70         80         90        100        110        120 
PAFATGKIIG VILFERTMRG KIEGMPTADF LWEKRHIVPF LKVDKGLQDE ANGVQLMKPF 

       130        140        150        160        170        180 
PELGKLCEEA VGYHVFGTKM RSVIKQANEQ GIRDIVEQQF QWGKEILSHG LVPILEPEVD 

       190        200        210        220        230        240 
IHCPEKAKAE EILKRELLAQ LDKMTEPVML KITIPTVDNF YKEIIEHPMM LRVVALSGGY 

       250        260        270        280        290 
SREQANELLS RNHGVIASFS RALVEGLSVQ QTDAEFNAML EASIEDVYQA SIK 

« Hide

References

[1]"Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis."
Naito M., Hirakawa H., Yamashita A., Ohara N., Shoji M., Yukitake H., Nakayama K., Toh H., Yoshimura F., Kuhara S., Hattori M., Hayashi T., Nakayama K.
DNA Res. 15:215-225(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33277 / DSM 20709 / JCM 12257.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009380 Genomic DNA. Translation: BAG34214.1.
RefSeqYP_001929811.1. NC_010729.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING431947.PGN_1695.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG34214; BAG34214; PGN_1695.
GeneID6328797.
KEGGpgn:PGN_1695.
PATRIC22976359. VBIPorGin26334_1670.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3588.
HOGENOMHOG000073502.
KOK01623.
OMAGTKMRSV.
OrthoDBEOG6M6JJT.
ProtClustDBPRK05377.

Enzyme and pathway databases

BioCycPGIN431947:GC9J-1748-MONOMER.
UniPathwayUPA00109; UER00183.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00729. FBP_aldolase_1.
InterProIPR000741. Aldolase_I.
IPR013785. Aldolase_TIM.
IPR023014. FBP_aldolase_I_bac.
[Graphical view]
PfamPF00274. Glycolytic. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALF1_PORG3
AccessionPrimary (citable) accession number: B2RLG9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: February 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways