B2RJT5 (B2RJT5_PORG3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Formate-tetrahydrofolate ligase EMBL BAG33630.1

Gene names

Ordered Locus Names:

PGN_1111

Organism

Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) [Complete proteome] [HAMAP]

Taxonomic identifier

431947 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas

Protein attributes

Sequence length	555 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate. SAAS SAAS020628
Pathway	One-carbon metabolism; tetrahydrofolate interconversion. SAAS SAAS020628

Ontologies

Keywords
Biological process	One-carbon metabolism SAAS SAAS020628
Ligand	ATP-binding SAAS SAAS020628 Nucleotide-binding
Molecular function	Ligase SAAS SAAS020628 EMBL BAG33630.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	folic acid-containing compound biosynthetic process Inferred from electronic annotation. Source: InterPro one-carbon metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW formate-tetrahydrofolate ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2RJT5 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 900DD71B42D28A9F	FASTA	555	60,075
	10 20 30 40 50 60 MKSDIQIARD IELQRIEQIA ESIDLPVEQL EPYGRYTAKV PLSCIDEEKV KKGNLILVTA 70 80 90 100 110 120 ITPNKAGVGK TTVSIGLALG LNHIGKKAIV ALREPSLGPC FGMKGGAAGG GYAQVLPMEN 130 140 150 160 170 180 INLHFTGDFH AVTSAHNMIT ALLENYIYQN RNTCDGLSEI LWKRVLDVND RSLRNAVTGL 190 200 210 220 230 240 GTISDGIPRQ TGFDITPASE IMAILCLAKD FEDLRSRLEN ILLGYTKEGA PFTVKDLGIA 250 260 270 280 290 300 GSIAVLLKDA IKPNLVQTTE HTPAFVHGGP FANIAHGCNS ILATKMALSF GEYAVTEAGF 310 320 330 340 350 360 GADLGAEKFL DIKCREMGVA PKLTVLVATL RALKLHGGVA ETEIKAPNAE ALRRGLSNLD 370 380 390 400 410 420 RHIYNLKKFG QQVIVAFNRF DTDEEEEISI VREHCIGQNV GFAVNNAFAE GGKGAEELAK 430 440 450 460 470 480 LVVEMVENKP SQPLKYAYEP ENPVKMKIEK IAKEIYSAGS VVYSSKADGK LKKIAMQSLD 490 500 510 520 530 540 HLPVCIAKTQ YSFSSDPKAK GDVRGFELKV SDIIINRGAG MLVVIIGEIM RMPGLPKEPQ 550 AVHIDIVDGF IEGLS

References

[1]

"Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis." Naito M., Hirakawa H., Yamashita A., Ohara N., Shoji M., Yukitake H., Nakayama K., Toh H., Yoshimura F., Kuhara S., Hattori M., Hayashi T., Nakayama K. DNA Res. 15:215-225(2008) [PubMed: 18524787] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33277 / DSM 20709 / JCM 12257.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009380 Genomic DNA. Translation: BAG33630.1.
RefSeq	YP_001929227.1. NC_010729.1.
3D structure databases
ProteinModelPortal	B2RJT5.
SMR	B2RJT5. Positions 4-553.
ModBase	Search...
Protein-protein interaction databases
STRING	B2RJT5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6330561.
GenomeReviews	Gene locus PGN_1111 in contig AP009380_GR.
KEGG	pgn:PGN_1111.
PATRIC	22975174. VBIPorGin26334_1097.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG677721.
OMA	EIMAVLC.
ProtClustDB	PRK13505.
Family and domain databases
HAMAP	MF_01543. FTHFS. [Tree]
InterPro	IPR000559. Formate_THF_ligase. IPR020628. Formate_THF_ligase_CS. [Graphical view]
KO	K01938.
Pfam	PF01268. FTHFS. 1 hit. [Graphical view]
PROSITE	PS00721. FTHFS_1. 1 hit. PS00722. FTHFS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2RJT5_PORG3

Accession

Primary (citable) accession number: B2RJT5

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)