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B2RJF8 (PSD_PORG3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:PGN_0984
OrganismPorphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) [Complete proteome] [HAMAP]
Taxonomic identifier431947 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Porphyromonas

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 188188Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131480
Chain189 – 22133Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131481

Sites

Site188 – 1892Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1891Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
B2RJF8 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 4C0A10DC316F1642

FASTA22124,519
        10         20         30         40         50         60 
MKVHKESTGL LVSMATLFTG ICLSLFYFLG ASIVSYLVMI IAIFLYLLTI NFFRCPKRHS 

        70         80         90        100        110        120 
PFANDDRAVV APADGKIVAI EEVSENEILH ERCIQVSIFM SIFNVHANWF PCEGKVTHVS 

       130        140        150        160        170        180 
HKNGHFIAAY LPKSSTDNER SAIVIKTEKG ARILARQIAG ALARRIVTYA EVGDICSVDA 

       190        200        210        220 
HMGFIKFGSR VDVYLPLGSQ VEVKMDQKTV GNQTLIARLP E

« Hide

References

[1]"Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis."
Naito M., Hirakawa H., Yamashita A., Ohara N., Shoji M., Yukitake H., Nakayama K., Toh H., Yoshimura F., Kuhara S., Hattori M., Hayashi T., Nakayama K.
DNA Res. 15:215-225(2008) [PubMed: 18524787] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33277 / DSM 20709 / JCM 12257.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009380 Genomic DNA. Translation: BAG33503.1.
RefSeqYP_001929100.1. NC_010729.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2RJF8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6328995.
GenomeReviewsGene locus PGN_0984 in contig AP009380_GR.
KEGGpgn:PGN_0984.
PATRIC22974918. VBIPorGin26334_0972.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG541103.
OMAIFMSVFN.
ProtClustDBPRK05305.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_PORG3
AccessionPrimary (citable) accession number: B2RJF8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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