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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPGIN431947:G1G2V-401-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:PGN_0365
OrganismiPorphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Taxonomic identifieri431947 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas
Proteomesi
  • UP000008842 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953901 – 597Arginine--tRNA ligaseAdd BLAST597

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi431947.PGN_0365

Structurei

3D structure databases

ProteinModelPortaliB2RHN9
SMRiB2RHN9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi125 – 135"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG

Family and domain databases

Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B2RHN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSILQKLENS AAAAVKALYG TDPMEGQIQL QKTKREFKGH LTLVVFPFVK
60 70 80 90 100
MSRKSPEATA TEIGEWLLAN ESAVSAIEVV KGFLNLTIAP RVWLELLNEI
110 120 130 140 150
RADINFGHKV ATEDSPLVMV EYSSPNTNKP LHLGHVRNNL LGYSLSEIMK
160 170 180 190 200
ANGYRVVKTN IVNDRGIHIC KSMLAWQKWG DGVTPEKAGK KGDHLIGDFY
210 220 230 240 250
VLFDKHYKAE LNSLMAEGKS KEEAEAASTL MAEAREMLRL WEAGDEKVVD
260 270 280 290 300
LWRTMNQWVY DGFEATYKMM GVDFDKIYYE SETYLVGKEE VLRGLEEGLF
310 320 330 340 350
VKHSDGSVWA DLTKDGLDEK LLLRADGTSV YMTQDIGTAK MRFNDYPINR
360 370 380 390 400
MIYVVGNEQN YHFQVLSILL DRLGFEFGKG LVHFSYGMVE LPEGKMKSRE
410 420 430 440 450
GTVVDADDLM DEMIRTAAEI AAEAGKAAEK DEEESREVAR IVGLGSLKYF
460 470 480 490 500
ILKVDPRKNM TFNPKESIDF NGNTGSFVQY TYARIRSLMR RAEAAGYDIP
510 520 530 540 550
SQLPTDLPLS EKEEALIQKV SEYAEVVSEA GRSYSPALIA NYIYDLVKEY
560 570 580 590
NQFYHDFSVL KEEDERIRAF RLALSEVVAL TMRKGFALLG IEMPERM
Length:597
Mass (Da):67,522
Last modified:July 1, 2008 - v1
Checksum:i6E9378412B9D88DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009380 Genomic DNA Translation: BAG32884.1
RefSeqiWP_012457453.1, NC_010729.1

Genome annotation databases

EnsemblBacteriaiBAG32884; BAG32884; PGN_0365
GeneIDi29255605
KEGGipgn:PGN_0365

Similar proteinsi

Entry informationi

Entry nameiSYR_PORG3
AccessioniPrimary (citable) accession number: B2RHN9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: February 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome