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B2RCU6

- B2RCU6_HUMAN

UniProt

B2RCU6 - B2RCU6_HUMAN

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Protein
Submitted name:

cDNA, FLJ96299, highly similar to Homo sapiens p21 (CDKN1A)-activated kinase 3 (PAK3), mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB2RCU6.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA, FLJ96299, highly similar to Homo sapiens p21 (CDKN1A)-activated kinase 3 (PAK3), mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA32919.

PTM / Processingi

Proteomic databases

PRIDEiB2RCU6.

Structurei

3D structure databases

ProteinModelPortaliB2RCU6.
SMRiB2RCU6. Positions 73-141, 247-538.

Family & Domainsi

Sequence similaritiesi

Contains CRIB domain.SAAS annotations
Contains protein kinase domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000234202.
HOVERGENiHBG108518.
KOiK05733.

Family and domain databases

Gene3Di3.90.810.10. 1 hit.
InterProiIPR000095. CRIB_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00786. PBD. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00285. PBD. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50108. CRIB. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2RCU6-1 [UniParc]FASTAAdd to Basket

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MSDGLDNEEK PPAPPLRMNS NNRDSSALNH SSKPLPMAPE EKNKKARLRS    50
IFPGGGDKTN KKKEKERPEI SLPSDFEHTI HVGFDAVTGE FTGIPEQWAR 100
LLQTSNITKL EQKKNPQAVL DVLKFYDSKE TVNNQKYMSF TSGDKSAHGY 150
IAAHPSSTKT ASEPPLAPPV SEEEDEEEEE EEDENEPPPV IAPRPEHTKS 200
IYTRSVVESI ASPAVPNKEV TPPSAENANS STLYRNTDRQ RKKSKMTDEE 250
ILEKLRSIVS VGDPKKKYTR FEKIGQGASG TVYTALDIAT GQEVAIKQMN 300
LQQQPKKELI INEILVMREN KNPNIVNYLD SYLVGDELWV VMEYLAGGSL 350
TDVVTETCMD EGQIAAVCRE CLQALDFLHS NQVIHRDIKS DNILLGMDGS 400
VKLTDFGFCA QITPEQSKRS TIVGTPYWMA PEVVTRKAYG PKVDIWSLGI 450
MAIEMVEGEP PYLNENPLRA LYLIATNGTP ELQNPERLSA VFRDFLNRCL 500
EMDVDRRGSA KELLQHPFLK LAKPLSSLTP LIIAAKEAIK NSSR 544
Length:544
Mass (Da):60,675
Last modified:July 1, 2008 - v1
Checksum:i25CAF45528B049E2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK315284 mRNA. Translation: BAG37693.1.
RefSeqiNP_001121638.1. NM_001128166.1.
UniGeneiHs.593599.
Hs.656789.

Genome annotation databases

GeneIDi5063.
KEGGihsa:5063.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK315284 mRNA. Translation: BAG37693.1 .
RefSeqi NP_001121638.1. NM_001128166.1.
UniGenei Hs.593599.
Hs.656789.

3D structure databases

ProteinModelPortali B2RCU6.
SMRi B2RCU6. Positions 73-141, 247-538.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B2RCU6.

Protocols and materials databases

DNASUi 5063.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5063.
KEGGi hsa:5063.

Organism-specific databases

CTDi 5063.
PharmGKBi PA32919.

Phylogenomic databases

HOGENOMi HOG000234202.
HOVERGENi HBG108518.
KOi K05733.

Enzyme and pathway databases

SignaLinki B2RCU6.

Miscellaneous databases

GenomeRNAii 5063.
NextBioi 19502.

Family and domain databases

Gene3Di 3.90.810.10. 1 hit.
InterProi IPR000095. CRIB_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00786. PBD. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00285. PBD. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50108. CRIB. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB2RCU6_HUMAN
AccessioniPrimary (citable) accession number: B2RCU6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: March 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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