B2RBY1 (B2RBY1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA, FLJ95762, highly similar to Homo sapiens interleukin 4 receptor (IL4R), mRNA EMBL BAG37378.1
Organism	Homo sapiens (Human) EMBL BAG37378.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	825 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL BAG37378.1
Gene Ontology (GO)
Biological_process	cytokine-mediated signaling pathway Inferred from electronic annotation. Source: GOC production of molecular mediator involved in inflammatory response Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	cytokine receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2RBY1 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: DACF16FA282391E7	FASTA	825	89,741
	10 20 30 40 50 60 MGWLCSGLLF PVSCLVLLQV ASSGNMKVLQ EPTCVSDYMS ISTCEWKMNG PTNCSTELRL 70 80 90 100 110 120 LYQLVFLLSE AHTCVPENNG GAGCVCHLLM DDVVSADNYT LDLWAGQQLL WKGSFKPSEH 130 140 150 160 170 180 VKPRAPGNLT VHTNVSDTLL LTWSNPYPPD NYLYNHLTYA VNIWSENDPA DFRIYNVTYL 190 200 210 220 230 240 EPSLRIAAST LKSGISYRAR VRAWAQCYNT TWSEWSPSTK WHNSYREPFE QHLLLGVSVS 250 260 270 280 290 300 CIVILAVCLL CYVSITKIKK EWWDQIPNPA RSRLVAIIIQ DAQGSQWEKR SRGQEPAKCP 310 320 330 340 350 360 HWKNCLTKLL PCFLEHNMKR DEDPHKAAKE MPFQGSGKSA WCPVEISKTV LWPESISVVR 370 380 390 400 410 420 CVELFEAPVE CEEEEEVEEE KGSFCASPES SRDDFQEGRE GIVARLTESL FLDLLGEENG 430 440 450 460 470 480 GFCQQDMGES CLLPPSGSTS AHMPWDEFPS AGPKEAPPWG KEQPLHLEPS PPASPTQSPD 490 500 510 520 530 540 NLTCTETPLV IAGNPAYRSF SNSLSQSPCP RELGPDPLLA RHLEEVEPEM PCVPQLSEPT 550 560 570 580 590 600 TVPQPEPETW EQILRRNVLQ HGAAAAPVSA PTSGYREFVH AVEQGGTQAS AVVGLGPPGE 610 620 630 640 650 660 AGYKAFSSLL ASRAVSPEKC GFGASSGEEG YKPFQDLIPG CPGDPAPVPV PLFTFGLDRE 670 680 690 700 710 720 PPRSPQSSHL PSSSPEHLGL EPGEKVEDMP KPPLPQEQAT DPLVDSLGSG IVYSALTCHL 730 740 750 760 770 780 CGHLKQCHGQ EDGGQTPVMA SPCCGCCCGD RSSPPTTPLR APDPSPGGVP LEASLCPASL 790 800 810 820 APSGISEKSK SSSSFHPAPG NAQSSSQTPK IVNFVSVGPT YMRVS

References

[1]

"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Tongue EMBL BAG37378.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK314863 mRNA. Translation: BAG37378.1.
IPI	IPI00444383.
RefSeq	NP_001244335.1. NM_001257406.1.
UniGene	Hs.513457. Hs.742121.
3D structure databases
ProteinModelPortal	B2RBY1.
SMR	B2RBY1. Positions 27-224.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3566.
KEGG	hsa:3566.
Organism-specific databases
CTD	3566.
Phylogenomic databases
HOVERGEN	HBG052116.
KO	K05071.
Family and domain databases
Gene3D	2.60.40.10. 2 hits.
InterPro	IPR003961. Fibronectin_type3. IPR003531. Hempt_rcpt_S_F1_CS. IPR013783. Ig-like_fold. IPR015319. IL4Ra_N. [Graphical view]
Pfam	PF09238. IL4Ra_N. 1 hit. [Graphical view]
SMART	SM00060. FN3. 1 hit. [Graphical view]
SUPFAM	SSF49265. FN_III-like. 2 hits.
PROSITE	PS50853. FN3. 1 hit. PS01355. HEMATOPO_REC_S_F1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	3566.
NextBio	13926.

Entry information

Entry name

B2RBY1_HUMAN

Accession

Primary (citable) accession number: B2RBY1

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	April 3, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.