B2R4C5 (B2R4C5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lysozyme EMBL ACO37637.1
EC=3.2.1.17 EMBL ACO37637.1

Submitted name:
Lysozyme (Renal amyloidosis), isoform CRA_a EMBL EAW97220.1
Submitted name:
cDNA, FLJ92040, Homo sapiens lysozyme (renal amyloidosis) (LYZ), mRNA EMBL BAG34722.1

Gene names

Name:	LYZ EMBL ACO37637.1
ORF Names:	hCG_24462 EMBL EAW97220.1

Organism

Homo sapiens (Human) EMBL BAG34722.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	148 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 22 family. RuleBase RU004440

Ontologies

Keywords
Molecular function	Glycosidase EMBL ACO37637.1 Hydrolase
PTM	Disulfide bond SAAS SAAS001916
Gene Ontology (GO)
Biological_process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	lysozyme activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2R4C5 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 8ECFD276BEB2678A	FASTA	148	16,537
	10 20 30 40 50 60 MKALIVLGLV LLSVTVQGKV FERCELARTL KRLGMDGYRG ISLANWMCLA KWESGYNTRA 70 80 90 100 110 120 TNYNAGDRST DYGIFQINSR YWCNDGKTPG AVNACHLSCS ALLQDNIADA VACAKRVVRD 130 140 PQGIRAWVAW RNRCQNRDVR QYVQGCGV

References

[1]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Lung EMBL BAG34722.1.
[3]	Guan W.J., Ma Y.H., Yu L.L. Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL ACO37637.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FJ795023 mRNA. Translation: ACO37637.1. AK311779 mRNA. Translation: BAG34722.1. CH471054 Genomic DNA. Translation: EAW97220.1.
IPI	IPI00019038.
RefSeq	NP_000230.1. NM_000239.2.
UniGene	Hs.524579.
3D structure databases
ProteinModelPortal	B2R4C5.
ModBase	Search...
Protein-protein interaction databases
STRING	B2R4C5.
Protein family/group databases
CAZy	GH22. Glycoside Hydrolase Family 22.
Proteomic databases
PRIDE	B2R4C5.
Protocols and materials databases
DNASU	4069.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4069.
KEGG	hsa:4069.
Organism-specific databases
CTD	4069.
PharmGKB	PA30503.
Phylogenomic databases
HOVERGEN	HBG052297.
KO	K13915.
OMA	CNALLQD.
PhylomeDB	B2R4C5.
Gene expression databases
ArrayExpress	B2R4C5.
Bgee	B2R4C5.
Family and domain databases
InterPro	IPR001916. Glyco_hydro_22. IPR019799. Glyco_hydro_22_CS. IPR000974. Glyco_hydro_22_lys. IPR023346. Lysozyme-like_dom. [Graphical view]
Pfam	PF00062. Lys. 1 hit. [Graphical view]
PRINTS	PR00137. LYSOZYME. PR00135. LYZLACT.
SMART	SM00263. LYZ1. 1 hit. [Graphical view]
SUPFAM	SSF53955. SSF53955. 1 hit.
PROSITE	PS00128. LACTALBUMIN_LYSOZYME_1. 1 hit. PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	LYZ. human.
GenomeRNAi	4069.
NextBio	15952.

Entry information

Entry name

B2R4C5_HUMAN

Accession

Primary (citable) accession number: B2R4C5

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.