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B2P6S8

- B2P6S8_ECO57

UniProt

B2P6S8 - B2P6S8_ECO57

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Protein
Peptidase T
Gene
pepT, ECH7EC4113_4569
Organism
Escherichia coli O157:H7 str. EC4113
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Cleaves the N-terminal amino acid of tripeptides By similarity.UniRule annotation

Catalytic activityi

Release of the N-terminal residue from a tripeptide.UniRule annotationSAAS annotations

Cofactori

Binds 2 zinc ions per subunit By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi78 – 781Zinc 1 By similarityUniRule annotation
Active sitei80 – 801 By similarityUniRule annotation
Metal bindingi140 – 1401Zinc 1 By similarityUniRule annotation
Metal bindingi140 – 1401Zinc 2 By similarityUniRule annotation
Active sitei173 – 1731Proton acceptor By similarityUniRule annotation
Metal bindingi174 – 1741Zinc 2 By similarityUniRule annotation
Metal bindingi196 – 1961Zinc 1 By similarityUniRule annotation
Metal bindingi379 – 3791Zinc 2 By similarityUniRule annotation

GO - Molecular functioni

  1. metallopeptidase activity Source: UniProtKB-KW
  2. tripeptide aminopeptidase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. peptide metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminopeptidaseUniRule annotationSAAS annotationsImported, Hydrolase, MetalloproteaseUniRule annotationSAAS annotations, Protease

Keywords - Ligandi

Metal-bindingUniRule annotationSAAS annotations, ZincUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidase TUniRule annotation (EC:3.4.11.4UniRule annotation)
Alternative name(s):
Aminotripeptidase
Tripeptide aminopeptidase
Gene namesi
Name:pepTUniRule annotationImported
ORF Names:ECH7EC4113_4569Imported
OrganismiEscherichia coli O157:H7 str. EC4113Imported
Taxonomic identifieri444452 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliB2P6S8.
SMRiB2P6S8. Positions 1-408.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M20B family.UniRule annotation

Phylogenomic databases

OMAiDCYIEVT.

Family and domain databases

Gene3Di3.30.70.360. 1 hit.
HAMAPiMF_00550. Aminopeptidase_M20.
InterProiIPR001261. ArgE/DapE_CS.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
IPR010161. Peptidase_M20B.
[Graphical view]
PfamiPF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view]
PIRSFiPIRSF037215. Peptidase_M20B. 1 hit.
SUPFAMiSSF55031. SSF55031. 1 hit.
TIGRFAMsiTIGR01882. peptidase-T. 1 hit.
PROSITEiPS00758. ARGE_DAPE_CPG2_1. 1 hit.
PS00759. ARGE_DAPE_CPG2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2P6S8-1 [UniParc]FASTAAdd to Basket

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MDKLLERFLN YVSLDTQSKA GVRQVPSTEG QWKLLHLLKE QLEEMGLINV    50
TLSEKGTLMA TLPANVPGDI PAIGFISHVD TSPDCSGKNV NPQIVENYRG 100
GDIALGIGDE VLSPVMFPVL HQLLGQTLIT TDGKTLLGAD DKAGIAEIMT 150
ALAVLQQKNI PHGDIRVAFT PDEEVGKGAK HFDVDAFDAR WAYTVDGGGV 200
GELEFENFNA ASVNIKIVGN NVHPGTAKGV MVNALSLAAR IHAEVPADES 250
PEMTEGYEGF YHLASMKGTV ERADMHYIIR DFDRKQFEAR KRKMMEIAKK 300
VGKGLHPDCY IELVIEDSYY NMREKVVEHP HILDIAQQAM RDCDIEPELK 350
PIRGGTDGAQ LSFMGLPCPN LFTGGYNYHG KHEFVTLEGM EKAVQVIVRI 400
AELTAQRK 408
Length:408
Mass (Da):44,909
Last modified:July 1, 2008 - v1
Checksum:i35744B1DF4CC1DA2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABHP01000017 Genomic DNA. Translation: EDU54147.1.

Genome annotation databases

EnsemblBacteriaiEDU54147; EDU54147; ECH7EC4113_4569.
PATRICi26598921. VBIEscCol134660_2699.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABHP01000017 Genomic DNA. Translation: EDU54147.1 .

3D structure databases

ProteinModelPortali B2P6S8.
SMRi B2P6S8. Positions 1-408.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EDU54147 ; EDU54147 ; ECH7EC4113_4569 .
PATRICi 26598921. VBIEscCol134660_2699.

Phylogenomic databases

OMAi DCYIEVT.

Family and domain databases

Gene3Di 3.30.70.360. 1 hit.
HAMAPi MF_00550. Aminopeptidase_M20.
InterProi IPR001261. ArgE/DapE_CS.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
IPR010161. Peptidase_M20B.
[Graphical view ]
Pfami PF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view ]
PIRSFi PIRSF037215. Peptidase_M20B. 1 hit.
SUPFAMi SSF55031. SSF55031. 1 hit.
TIGRFAMsi TIGR01882. peptidase-T. 1 hit.
PROSITEi PS00758. ARGE_DAPE_CPG2_1. 1 hit.
PS00759. ARGE_DAPE_CPG2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Rosovitz M.J., Ravel J.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: EC4113Imported.
  2. "Annotation of Escherichia coli O157:H7 str. EC4113."
    Eppinger M., Ravel J., Mammel M.K., LeClerc J.E., Cebula T.A., Sebastian Y.
    Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: EC4113Imported.

Entry informationi

Entry nameiB2P6S8_ECO57
AccessioniPrimary (citable) accession number: B2P6S8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: July 9, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

External Data

Dasty 3

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