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B2P6S8 (B2P6S8_ECO57) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptidase T HAMAP-Rule MF_00550
EC=3.4.11.4 HAMAP-Rule MF_00550
Alternative name(s):
Aminotripeptidase HAMAP-Rule MF_00550
Tripeptide aminopeptidase HAMAP-Rule MF_00550
Gene names
Name:pepT HAMAP-Rule MF_00550 EMBL EDU54147.1
ORF Names:ECH7EC4113_4569 EMBL EDU54147.1
OrganismEscherichia coli O157:H7 str. EC4113 EMBL EDU54147.1
Taxonomic identifier444452 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cleaves the N-terminal amino acid of tripeptides By similarity. HAMAP-Rule MF_00550

Catalytic activity

Release of the N-terminal residue from a tripeptide. HAMAP-Rule MF_00550 SAAS SAAS010161

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP-Rule MF_00550 SAAS SAAS010161

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00550 SAAS SAAS010161.

Sequence similarities

Belongs to the peptidase M20B family. HAMAP-Rule MF_00550

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site801 By similarity HAMAP-Rule MF_00550
Active site1731Proton acceptor By similarity HAMAP-Rule MF_00550
Metal binding781Zinc 1 By similarity HAMAP-Rule MF_00550
Metal binding1401Zinc 1 By similarity HAMAP-Rule MF_00550
Metal binding1401Zinc 2 By similarity HAMAP-Rule MF_00550
Metal binding1741Zinc 2 By similarity HAMAP-Rule MF_00550
Metal binding1961Zinc 1 By similarity HAMAP-Rule MF_00550
Metal binding3791Zinc 2 By similarity HAMAP-Rule MF_00550

Sequences

Sequence LengthMass (Da)Tools
B2P6S8 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 35744B1DF4CC1DA2

FASTA40844,909
        10         20         30         40         50         60 
MDKLLERFLN YVSLDTQSKA GVRQVPSTEG QWKLLHLLKE QLEEMGLINV TLSEKGTLMA 

        70         80         90        100        110        120 
TLPANVPGDI PAIGFISHVD TSPDCSGKNV NPQIVENYRG GDIALGIGDE VLSPVMFPVL 

       130        140        150        160        170        180 
HQLLGQTLIT TDGKTLLGAD DKAGIAEIMT ALAVLQQKNI PHGDIRVAFT PDEEVGKGAK 

       190        200        210        220        230        240 
HFDVDAFDAR WAYTVDGGGV GELEFENFNA ASVNIKIVGN NVHPGTAKGV MVNALSLAAR 

       250        260        270        280        290        300 
IHAEVPADES PEMTEGYEGF YHLASMKGTV ERADMHYIIR DFDRKQFEAR KRKMMEIAKK 

       310        320        330        340        350        360 
VGKGLHPDCY IELVIEDSYY NMREKVVEHP HILDIAQQAM RDCDIEPELK PIRGGTDGAQ 

       370        380        390        400 
LSFMGLPCPN LFTGGYNYHG KHEFVTLEGM EKAVQVIVRI AELTAQRK

« Hide

References

[1]Rosovitz M.J., Ravel J.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: EC4113 EMBL EDU54147.1.
[2]"Annotation of Escherichia coli O157:H7 str. EC4113."
Eppinger M., Ravel J., Mammel M.K., LeClerc J.E., Cebula T.A., Sebastian Y.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: EC4113 EMBL EDU54147.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		ABHP01000017 Genomic DNA. Translation: EDU54147.1.

3D structure databases

ProteinModelPortalB2P6S8.
SMRB2P6S8. Positions 1-408.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEDU54147; EDU54147; ECH7EC4113_4569.
PATRIC26598921. VBIEscCol134660_2699.

Phylogenomic databases

OMAYVYATIP.

Family and domain databases

HAMAPMF_00550. Aminopeptidase_M20.
InterProIPR001261. ArgE/DapE_CS.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
IPR010161. Peptidase_M20B.
[Graphical view]
PfamPF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view]
PIRSFPIRSF037215. Peptidase_M20B. 1 hit.
SUPFAMSSF55031. Peptidase_M20_dimer. 1 hit.
TIGRFAMsTIGR01882. peptidase-T. 1 hit.
PROSITEPS00758. ARGE_DAPE_CPG2_1. 1 hit.
PS00759. ARGE_DAPE_CPG2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2P6S8_ECO57
AccessionPrimary (citable) accession number: B2P6S8
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 3, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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