B2NKQ3 (B2NKQ3_ECO57) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
L-lactate dehydrogenase (Cytochrome) EMBL EDU35502.1
EC=1.1.2.3 EMBL EDU35502.1

Gene names

Name:	lldD EMBL EDU35502.1
ORF Names:	ECH7EC4196_5054 EMBL EDU35502.1

Organism

Escherichia coli O157:H7 str. EC4196 EMBL EDU35502.1

Taxonomic identifier

444451 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H+. SAAS SAAS020920
Cofactor	FMN By similarity. SAAS SAAS020920
Sequence similarities	Contains 1 FMN hydroxy acid dehydrogenase domain. SAAS SAAS020920

Ontologies

Keywords
Ligand	FMN SAAS SAAS020920 Flavoprotein SAAS SAAS020920
Molecular function	Oxidoreductase SAAS SAAS020920 EMBL EDU35502.1
Gene Ontology (GO)
Biological process	lactate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	FMN binding Inferred from electronic annotation. Source: InterPro L-lactate dehydrogenase (cytochrome) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2NKQ3 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: CA0D8E208613BF83	FASTA	396	42,758
	10 20 30 40 50 60 MIISAASDYR AAAQRILPPF LFHYMDGGAY SEYTLRRNVE DLSEVALRQR ILKNMSDLSL 70 80 90 100 110 120 ETTLFNEKLS MPVALAPVGL CGMYARRGEV QAAKAADAHG IPFTLSTVSV CPIEEVAPAI 130 140 150 160 170 180 KRPMWFQLYV LRDRGFMRNA LERAKAAGCS TLVFTVDMPT PGARYRDAHS GMSGPNAAMR 190 200 210 220 230 240 RYLQAVTHPQ WAWDVGLNGR PHDLGNISAY LGKPTGLEDY IGWLGNNFDP SISWKDLEWI 250 260 270 280 290 300 RDFWDGPMVI KGILDPEDAR DAVRFGADGI VVSNHGGRQL DGVLSSARAL PAIADAVKGD 310 320 330 340 350 360 IAILADSGIR NGLDVVRMIA LGADTVLLGR AFLYALATAG QAGVANLLNL IEKEMKVAMT 370 380 390 LTGAKSISEI TQDSLVQGLG KELPTALAPM AKGNAA

References

[1]	"Annotation of Escherichia coli O157:H7 str. EC4196." Eppinger M., Ravel J., Mammel M.K., LeClerc J.E., Cebula T.A., Sebastian Y. Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: EC4196 EMBL EDU35502.1.
[2]	Rosovitz M.J., Ravel J. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: EC4196 EMBL EDU35502.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABHO01000001 Genomic DNA. Translation: EDU35502.1.
3D structure databases
ProteinModelPortal	B2NKQ3.
SMR	B2NKQ3. Positions 3-377.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26605986. VBIEscCol79648_0193.
Phylogenomic databases
OMA	IGWLTEN.
Family and domain databases
HAMAP	MF_01559. L_lact_dehydr. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR012133. Alpha-hydoxy_acid_DH_FMN. IPR000262. FMN-dep_DH. IPR008259. FMN_hydac_DH_AS. IPR020920. L-lactate_DHase_cyt. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF01070. FMN_dh. 1 hit. [Graphical view]
PIRSF	PIRSF000138. Al-hdrx_acd_dh. 1 hit.
PROSITE	PS00557. FMN_HYDROXY_ACID_DH_1. 1 hit. PS51349. FMN_HYDROXY_ACID_DH_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2NKQ3_ECO57

Accession

Primary (citable) accession number: B2NKQ3

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)