B2N6Z9 (B2N6Z9_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase HAMAP MF_01605
Short name=6-P-gluconolactonase HAMAP MF_01605
EC=3.1.1.31 HAMAP MF_01605

Gene names

Name:	pgl HAMAP MF_01605
ORF Names:	Ec53638_0539 EMBL EDU64836.1

Organism

Escherichia coli 53638 EMBL EDU64836.1

Taxonomic identifier

344610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605 SAAS SAAS019405
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605 SAAS SAAS019405
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605 SAAS SAAS019405
Sequence similarities	Belongs to the cycloisomerase 2 family. HAMAP MF_01605

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism HAMAP MF_01605 SAAS SAAS019405
Molecular function	Hydrolase HAMAP MF_01605 SAAS SAAS019405 Isomerase EMBL EDU64836.1
PTM	Acetylation HAMAP MF_01605
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	287	1	N6-acetyllysine By similarity HAMAP MF_01605

Sequences

	Sequence		Length	Mass (Da)
	B2N6Z9 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: D731044CFCF31A8F	FASTA	331	36,308
	10 20 30 40 50 60 MKQTVYIASP ESQQIHVWNL NHEGALTLTQ VVDVPGQVQP MVVSPDKRYL YVGVRPEFRV 70 80 90 100 110 120 LAYRIAPDDG ALTFAAESAL PGSPTHISTD HQGQFVFVGS YNAGNVSVTR LEDGLPVGVV 130 140 150 160 170 180 DVVEGLDGCH SANISPDNRT LWVPALKQDR ICLFTVSDDG HLVAQDPAEV TTVEGAGPRH 190 200 210 220 230 240 MVFHPNEQYA YCVNELNSSV DVWELKDPHG NIECVQTLDM MPENFSDTRW AADIHITPDG 250 260 270 280 290 300 RHLYACDRTA SLITVFSVSE DGSVLSKEGF QPTETQPRGF NVDHSGKYLI AAGQKSHHIS 310 320 330 VYEIVGEQGL LHEKGRYAVG QGPMWVVVNA H

References

[1]	Rasko D.A., Rosovitz M.J., Brinkley C., Myers G.S.A., Seshadri R., Cer R.Z., Jiang L., Sebastian Y., Ravel J. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 53638 EMBL EDU64836.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAKB02000001 Genomic DNA. Translation: EDU64836.1.
3D structure databases
ProteinModelPortal	B2N6Z9.
SMR	B2N6Z9. Positions 1-331.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	31207631. VBIEscCol26876_0925.
Family and domain databases
HAMAP	MF_01605. 6P_gluconolactonase. [Tree]
InterPro	IPR022528. 6-phosphogluconolactonase_YbhE. IPR019405. Lactonase_7-beta_prop. IPR011045. N2O_reductase_N. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF10282. Lactonase. 1 hit. [Graphical view]
SUPFAM	SSF50974. N2O_reductase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2N6Z9_ECOLX

Accession

Primary (citable) accession number: B2N6Z9

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)