B2MUU6 (GTF1_LEUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Dextransucrase 1
EC=2.4.1.5

Alternative name(s):
Glucansucrase 1
Sucrose 6-glucosyltransferase 1

Gene names

Name:

dsrF

Organism

Leuconostoc mesenteroides

Taxonomic identifier

1245 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Leuconostocaceae › Leuconostoc

Protein attributes

Sequence length	284 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the production of dextran, an extracellular glucan polymer By similarity.
Catalytic activity	Sucrose + ((1->6)-alpha-D-glucosyl)(n) = D-fructose + ((1->6)-alpha-D-glucosyl)(n+1).
Miscellaneous	The dextran produced by Leuconostoc mesenteroides CMG713 has a molecular mass of about 2000 kDa and contains exclusively alpha-(1->6) glycosidic linkages in the main chain.
Sequence similarities	Belongs to the glycosyl hydrolase 70 family.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Gene Ontology (GO)
Biological_process	glucan biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	dextransucrase activity Inferred from electronic annotation. Source: EC glucosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›284	›284	Dextransucrase 1		PRO_0000403441
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	284	1

Sequences

	Sequence		Length	Mass (Da)
	B2MUU6 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: F6228D1BE8189CF0	FASTA	284	30,936
	10 20 30 40 50 60 DTVPRVYYAD LYTDDGQYMA TKSPFFDAIN TLLKARVQYV AGGQSMSVDS NDVLTSVRYG 70 80 90 100 110 120 KNAMTASDTG TSETRTEGVG VIVSNNAELQ LEDGHTVTLH MGAAHKNQAY RALLSTTADG 130 140 150 160 170 180 LAYYDTDENA PVAYTDANGD LIFTNESIYG VQNPQVSGYL AVWVPVGAQQ DQDARTASDT 190 200 210 220 230 240 TTNTSDKVFH SNAALDSQVI YEGFSNFQAF ATDSSEYTNV VIAQNADQFK QWGVTSFQLA 250 260 270 280 PQYRSSTDTS FLDSIIQNGY AFTDRYDLGY GTPTQYGAVD HVRA

References

[1]	Sarwat F. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: CMG713.
[2]	"Production & characterization of a unique dextran from an indigenous Leuconostoc mesenteroides CMG713." Sarwat F., Ul Qader S.A., Aman A., Ahmed N. Int. J. Biol. Sci. 4:379-386(2008) [PubMed] [Europe PMC] [Abstract] Cited for: CHARACTERISTICS OF DEXTRAN. Strain: CMG713.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU621844 Genomic DNA. Translation: ACC65964.1.
3D structure databases
ProteinModelPortal	B2MUU6.
ModBase	Search...
Protein family/group databases
CAZy	GH70. Glycoside Hydrolase Family 70.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.20.20.80. 1 hit.
InterPro	IPR003318. Glyco_hydro70cat. IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Pfam	PF02324. Glyco_hydro_70. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GTF1_LEUME

Accession

Primary (citable) accession number: B2MUU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2011
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program