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Protein
Submitted name:

Laccase

Gene

Lac

Organism
Trametes hirsuta (White-rot fungus) (Coriolus hirsutus)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei28Mannose; via amide nitrogenCombined sources1
Metal bindingi85Copper 1; via tele nitrogenCombined sources1
Metal bindingi87Copper 1Combined sources1
Metal bindingi87Copper 2; via pros nitrogenCombined sources1
Metal bindingi130Copper 2; via tele nitrogenCombined sources1
Metal bindingi132Copper 3; via tele nitrogenCombined sources1
Metal bindingi416Copper 4; via pros nitrogenCombined sources1
Metal bindingi419Copper 1; via tele nitrogenCombined sources1
Metal bindingi419Copper 3; via pros nitrogenCombined sources1
Metal bindingi421Copper 3; via tele nitrogenCombined sources1
Metal bindingi473Copper 3; via tele nitrogenCombined sources1
Metal bindingi474Copper 4Combined sources1
Metal bindingi475Copper 2; via tele nitrogenCombined sources1
Metal bindingi479Copper 4; via pros nitrogenCombined sources1
Binding sitei481MannoseCombined sources1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseSAAS annotationImported
LigandCopperCombined sourcesSAAS annotation, Metal-bindingCombined sourcesSAAS annotation

Protein family/group databases

CAZyiAA1. Auxiliary Activities 1.

Names & Taxonomyi

Protein namesi
Submitted name:
LaccaseImported (EC:1.10.3.2Imported)
Gene namesi
Name:LacImported
OrganismiTrametes hirsuta (White-rot fungus) (Coriolus hirsutus)Imported
Taxonomic identifieri5327 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesPolyporalesPolyporaceaeTrametes

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500277842322 – 520Sequence analysisAdd BLAST499

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi75N-linked (GlcNAc...)Combined sources1
Disulfide bondi106 ↔ 509Combined sources
Disulfide bondi138 ↔ 226Combined sources
Glycosylationi238N-linked (GlcNAc...)Combined sources1
Glycosylationi354N-linked (GlcNAc...)Combined sources1
Glycosylationi457N-linked (GlcNAc...)Combined sources1

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3FPXX-ray1.80A22-520[»]
3PXLX-ray1.20A22-520[»]
3V9CX-ray2.00A22-520[»]
SMRiB2L9C1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiB2L9C1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 151Plastocyanin-likeInterPro annotationAdd BLAST121
Domaini164 – 305Plastocyanin-likeInterPro annotationAdd BLAST142
Domaini366 – 492Plastocyanin-likeInterPro annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni41 – 44Mannose bindingCombined sources4
Regioni60 – 66Mannose bindingCombined sources7

Sequence similaritiesi

Belongs to the multicopper oxidase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiView protein in InterPro
IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR008972. Cupredoxin.
PfamiView protein in Pfam
PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
SUPFAMiSSF49503. SSF49503. 3 hits.
PROSITEiView protein in PROSITE
PS00079. MULTICOPPER_OXIDASE1. 1 hit.

Sequencei

Sequence statusi: Complete.

B2L9C1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRFQSLLTF INISLVAVAH AAVGPVADLT ITDAAVSPDG FSRQAVVVNG
60 70 80 90 100
VTPGPLVAGN IGDRFQLNVI DNLTNHTMLK STSIHWHGFF QHGTNWADGP
110 120 130 140 150
AFINQCPISP GHSFLYDFQV PDQAGTFWYH SHLSTQYCDG LRGPFVVYDP
160 170 180 190 200
NDPHASRYDV DNDDTVITLA DWYHTAAKLG PRFPGGADAT LINGKGRAPS
210 220 230 240 250
DSPAELSVIK VTKGKRYRFR LVSLSCNPNH TFSIDGHNLT IIEVDSVNSQ
260 270 280 290 300
PLEVDSIQIF AAQRYSFVLD ANQAVDNYWI RANPNFGNVG FDGGINSAIL
310 320 330 340 350
RYDGAPAVEP TTNQTTSVKP LNEVDLHPLV STPVPGSPSS GGVDKAINMA
360 370 380 390 400
FNFNGSNFFI NGASFVPPTV PVLLQILSGA QTAQDLLPSG SVYVLPSNAS
410 420 430 440 450
IEISFPATAA APGAPHPFHL HGHTFAVVRS AGSTVYNYDN PIFRDVVSTG
460 470 480 490 500
TPAAGDNVTI RFDTNNPGPW FLHCHIDFHL EGGFAVVMAE DTPDVKAVNP
510 520
VPQAWSDLCP TYDALDPNDQ
Length:520
Mass (Da):55,904
Last modified:June 10, 2008 - v1
Checksum:iD4EA73621F1B34A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU492907 Genomic DNA. Translation: ACC43989.1.

Similar proteinsi

Entry informationi

Entry nameiB2L9C1_TRAHI
AccessioniPrimary (citable) accession number: B2L9C1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: October 25, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources